Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gerard Normier"'
Autor:
Hans Wigzell, Lucien Dussourd D'hinterland, Robert Fontanges, Daniel Robert, Sergyl Lafont, Gerard Normier
Publikováno v:
Acta Pathologica Microbiologica Scandinavica Series C: Immunology. :293-299
Ribosomes, ribosomal RNA (r-RNA), capsular polysaccharide (PS-K) and lipopolysaccharide (LPS) were isolated and purified from Klebsiella pneumoniae, type I. The protective capacity of these different fractions was investigated in function of their an
Publikováno v:
Acta Pathologica Microbiologica Scandinavica Series C: Immunology. :233-243
Upon testing the individual fractions of a composite bacterial vaccine for biological activities, a potent immuno-stimulatory capacity could be demonstrated within a crude membrane proteoglycan preparation from Klebsiella pneumoniae. One of its chara
Publikováno v:
Journal of Leukocyte Biology
Journal of Leukocyte Biology, Society for Leukocyte Biology, 1997, 61 (1), pp.17-23. ⟨10.1002/jlb.61.1.17⟩
Journal of Leukocyte Biology, Society for Leukocyte Biology, 1997, 61 (1), pp.17-23. ⟨10.1002/jlb.61.1.17⟩
The acyl poly(l,3)galactoside (APG) from Klebsiella pneumoniae is a bis-acylated lipopolysaccharide (LPS) devoid of ester-linked fatty acids. APG interacts with CD14 and CD11b/CD18 on monocytes. This study addressed the role of serum proteins in the
Publikováno v:
International Journal of Immunopharmacology
International Journal of Immunopharmacology, Elsevier, 1994, 16 (5-6), pp.413-417. ⟨10.1016/0192-0561(94)90030-2⟩
International Journal of Immunopharmacology, 1994, 16 (5-6), pp.413-417. ⟨10.1016/0192-0561(94)90030-2⟩
International Journal of Immunopharmacology, Elsevier, 1994, 16 (5-6), pp.413-417. ⟨10.1016/0192-0561(94)90030-2⟩
International Journal of Immunopharmacology, 1994, 16 (5-6), pp.413-417. ⟨10.1016/0192-0561(94)90030-2⟩
The induction of TNF alpha synthesis in whole blood culture assay and isolated peripheral blood mononuclear cells was investigated, using LPS from Klebsiella pneumoniae and two water-soluble 34 kDa derivatives designed as acylpolygalactoside (APG) an
Autor:
Jean Louis Banlieu, Gerard Normier, Jean Pierre Revillard, Sophie Pascal, Putrice Diot, Alain Le Pape, Etienne Lemarié, Loic Vaillant, Hans Binz
Publikováno v:
Chest. 102:670-676
Scintigraphy with radiolabeled J001 as a ligand for macrophage targeting is a new approach for sarcoidosis imaging. J001 is a fully characterized acylated peptido-poly (1,3) galactoside isolated from Klebsiella membrane proteoglycans and able to bind
Publikováno v:
Nuclear medicine and biology. 23(8)
The potential of 99m-Tc-J001 for the investigation of inflammatory lesions via the targeting of recruited macrophages (M phi) has already been documented in several experimental models and in human diseases. To achieve a functional imaging of inflamm
Autor:
J.-C. Pittet, F. Perin, Alain Le Pape, Hans Binz, D. Hoffschir, François Daburon, Gerard Normier
Publikováno v:
Nuclear medicine and biology. 21(8)
J001X, an acylated poly-(1,3)-galactoside isolated from Klebsiella pneumoniae proteoglycan, has been developed to target cells from the monocyte-macrophage lineage. Recent experimental work and initial clinical trials have proved the potential of thi
Autor:
Z. Hmama, F Faure-Barba, H Binz, E Kouassi, Gerard Normier, Gerard Lina, Jean-Pierre Revillard, J. Vial
Publikováno v:
Scopus-Elsevier
The stimulating activity of several preparations isolated from a membrane proteoglycan of a nonen- capsulated smooth strain of Klebsiella pneumoniae (Kp- MPG) on the oxidative burst of human blood monocytes was assessed by luminol-enhanced chemilumin
Autor:
Claude Vincent, J. Wijdenes, Jean-Pierre Revillard, Gerard Normier, Gerard Lina, Z. Hmama, H Binz
Publikováno v:
Clinical and experimental immunology. 89(1)
SUMMARYThe capacity of a K. pneumoniae membrane proteoglycan (Kp-MPG) and four of its chemically defined derivatives to activate human monocytes was studied by measuring immunoreactive IL-1β, IL-6 and tumour necrosis factor-alpha (TNF-α) in culture
Autor:
Isabelle Millet, Lucien Dussourd D'hinterland, Sergyl Lafont, Michèle Jeannin, Jean-Pierre Revillard, Gerard Normier
Publikováno v:
International Archives of Allergy and Immunology. 86:432-435
The in vitro lymphocyte-activating properties of a ribosomal preparation of Streptococcus pyogenes were investigated. The preparation was mitogenic for human lymphocytes with a peak of 3H-thymidine incorporation occurring after 3–5 days of culture.