Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Gerard Marriott"'
Autor:
Jiayi Zhang, Annie Brown, Brendan Johnson, David Diebold, Kyle Asano, Gerard Marriott, Biao Lu
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2564 (2022)
Background: Human cell-secreted extracellular vesicles (EVs) are versatile nanomaterials suitable for disease-targeted drug delivery and therapy. Native EVs, however, usually do not interact specifically with target cells or harbor therapeutic drugs,
Externí odkaz:
https://doaj.org/article/36f49825cb52480ab8b91310064db282
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/8f9d276c21d64f3482725f862ec3a3ad
Publikováno v:
ACS Central Science, Vol 4, Iss 12, Pp 1677-1687 (2018)
Externí odkaz:
https://doaj.org/article/9ad41f1114824036a57c509ee0c150ae
Autor:
Zhen Cheng, Gerard Marriott
Publikováno v:
Frontiers in Physics, Vol 7 (2019)
Externí odkaz:
https://doaj.org/article/44e822e3f0d344a7868e87885707337a
Autor:
Liangxing Wu, Yingrui Dai, Xiaoli Jiang, Chutima Petchprayoon, Jessie E Lee, Tao Jiang, Yuling Yan, Gerard Marriott
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64738 (2013)
We present the design, synthesis and characterization of new functionalized fluorescent optical switches for rapid, all-visible light-mediated manipulation of fluorescence signals from labelled structures within living cells, and as probes for high-c
Externí odkaz:
https://doaj.org/article/87d7fdbb9acd4bb897a748245cae823e
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50420 (2012)
A multi-site, steady-state Förster resonance energy transfer (FRET) approach was used to quantify Ca(2+)-induced changes in proximity between donor loci on human cardiac troponin I (cTnI), and acceptor loci on human cardiac tropomyosin (cTm) and F-a
Externí odkaz:
https://doaj.org/article/329b2f975d874a9e9808847ae6f9a4e2
Autor:
Yu-Hui Gong, Gerard Marriott
Publikováno v:
ACS Sensors. 5:180-190
Current interest in at-home diagnostic devices derives from their potential to disrupt expensive and time-consuming hospital-based diagnostic practices. Conventional immunoassays are often touted for use in at-home diagnostic devices, although in pra
Exosome- and extracellular vesicle-based approaches for the treatment of lysosomal storage disorders
Publikováno v:
Advanced Drug Delivery Reviews. 188:114465
Cell-generated extracellular vesicles (EVs) are being engineered as biologically-inspired vehicles for targeted delivery of therapeutic agents to treat difficult-to-manage human diseases, including lysosomal storage disorders (LSDs). Engineered EVs o
Publikováno v:
Progress in Materials Science. 103:678-742
Mechanoluminescence (ML) is generated during exposures of certain materials to mechanical stimuli. Many solid materials produce ML during their fracturing, however, the irreversibility of fracto-induced ML limits the practical applications of these m
Autor:
Daniel P. Levy, Adarsh Tantry, Natalie Duong, Biao Lu, Mai Anh Do, Alexander Campanelli, Annie Brown, Gerard Marriott, Kevin Curley
Publikováno v:
International Journal of Nanomedicine. 14:3413-3425
Background: Exosomes are ubiquitous naturally secreted stable nanovesicles that can be engineered to target and deliver novel therapeutics to treat a host of human diseases. Methods: We engineered the surfaces of cell-derived nanovesicles to act as d