Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Gerard M J, Bos"'
Autor:
Monique C. Minnema, Kazem Nasserinejad, Ute Hegenbart, Paula F. Ypma, Ka Lung Wu, Marie Jose Kersten, Sandra Croockewit, Sonja Zweegman, Lidwine Tick, Annemiek Broijl, Harry Koene, Gerard M. J. Bos, Pieter Sonneveld, Stefan O. Schönland
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 815-819 (2024)
Abstract The HOVON 104 studied bortezomib‐dexamethasone induction therapy and autologous stem cell transplantation in 50 patients, of whom 35 received an autologous stem cell transplantation (ASCT). We demonstrate a 5‐year overall survival (OS) o
Externí odkaz:
https://doaj.org/article/601abdedab4a41ad8368ea73a9b0936d
Autor:
Nicky A. Beelen, Merel R. Aberle, Virginia Bruno, Steven W. M. Olde Damink, Gerard M. J. Bos, Sander S. Rensen, Lotte Wieten
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPancreatic cancer is associated with poor prognosis, and limited treatment options are available for the majority of patients. Natural killer (NK) cells in combination with antibodies inducing antibody-dependent cell-mediated cytotoxicity
Externí odkaz:
https://doaj.org/article/3c10e782dbc3415d8328e513b34bf6c8
Autor:
Ying Gong, Roel G. J. Klein Wolterink, Jianxiang Wang, Gerard M. J. Bos, Wilfred T. V. Germeraad
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-35 (2021)
Abstract Due to their efficient recognition and lysis of malignant cells, natural killer (NK) cells are considered as specialized immune cells that can be genetically modified to obtain capable effector cells for adoptive cellular treatment of cancer
Externí odkaz:
https://doaj.org/article/6c31255476e94becb8ad5d79bda37f27
Autor:
Gwendolyn N. Y. van Gorkom, Lara S. Boerenkamp, Birgit L. M. G. Gijsbers, Heidi H. van Ojik, Will K. W. H. Wodzig, Lotte Wieten, Catharina H. M. J. Van Elssen, Gerard M. J. Bos
Publikováno v:
Nutrients, Vol 14, Iss 22, p 4784 (2022)
Vitamin C is an important micronutrient for various immune cells. It increases phagocytic cell function and is necessary for T and natural killer (NK) cell development. Patients in need of an autologous hematopoietic stem cell transplantation (HSCT)
Externí odkaz:
https://doaj.org/article/8c2d7fb2f72f43b9b42ac4ecf21b5ca1
Autor:
Paul A. F. Geerts, Trudy van der Weijden, Pien G. M. Loeffen, Lise E. F. Janssen, Celine Almekinders, Tobias A. Wienhold, Gerard M. J. Bos
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Electronic patient portals are increasingly being implemented, also in (haemato) oncology. However, portal usage is low and depends on user and provider engagement. We explored wishes, expectations and thoughts of patients with a
Externí odkaz:
https://doaj.org/article/3cfa8226ada049f7b00c8ae891b6191c
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Infusion of ex vivo expanded and cytokine-activated natural killer (NK) cells is a promising alternative way to treat multiple myeloma (MM). However, the tumor microenvironment (TME) may suppress their function. While reduced glucose availability is
Externí odkaz:
https://doaj.org/article/2e461f38d3cc4cb1bec75082dd3669d8
Autor:
Femke A. I. Ehlers, Niken M. Mahaweni, Annet van de Waterweg Berends, Thara Saya, Gerard M. J. Bos, Lotte Wieten
Publikováno v:
Cancer Immunology Immunotherapy, 72(6), 1789-1801. Springer
Multiple myeloma (MM) is an incurable disease, characterized by malignant plasma cells in the bone marrow. MM growth is largely dependent on the tumor microenvironment (TME), consisting of complex cellular networks that shape a tumor-permissive envir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2a32996b7b81b20276b1acf247d29a
https://doi.org/10.1007/s00262-022-03365-4
https://doi.org/10.1007/s00262-022-03365-4
Autor:
Tammy Oth, Thomas H. P. M. Habets, Wilfred T. V. Germeraad, Marijke I. Zonneveld, Gerard M. J. Bos, Joris Vanderlocht
Publikováno v:
BMC Immunology, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Besides their prominent role in the elimination of infected or malignantly transformed cells, natural killer (NK) cells serve as modulators of adaptive immune responses. Enhancing bidirectional crosstalk between NK cells and dendr
Externí odkaz:
https://doaj.org/article/0626c82c7482453e9eb0f80a81265a07
Autor:
Femke A. I. Ehlers, Timo I. Olieslagers, Mathijs Groeneweg, Gerard M. J. Bos, Marcel G. J. Tilanus, Christina E. M. Voorter, Lotte Wieten
Publikováno v:
HLA, 100(3), 232-243. Wiley
The human leukocyte antigen (HLA) genes are amongst the most polymorphic in the human genome. Alternative splicing could add an extra layer of complexity, but has not been studied extensively. Here, we applied an RNA based approach to study the influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128dec4e576379ee11fcdea238c80942
https://doi.org/10.1111/tan.14695
https://doi.org/10.1111/tan.14695
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Natural killer (NK) cells are attractive candidates for allogeneic cell-based immunotherapy due to their potent antitumor effector function and good safety profile. NK cells express killer immunoglobulin-like receptors (KIRs) and the NKG2A receptor i
Externí odkaz:
https://doaj.org/article/9cb1443d088b472697192f69a330f364