Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gerard Le Fur"'
Autor:
Gerard Le Fur, Kenzie L. Preston, Marilyn A. Huestis, Stephen J. Heishman, Denis Bonnet, Susan J. Boyd, David A. Gorelick
Publikováno v:
Psychopharmacology. 194:505-515
A single 90-mg dose of the cannabinoid CB1 receptor antagonist rimonabant attenuates effects of smoked cannabis in humans.The objective of this study is to evaluate whether repeated daily 40-mg doses of rimonabant can attenuate effects of smoked cann
Autor:
Frédéric, Béquet, Françoise, Uzabiaga, Mathieu, Desbazeille, Pascal, Ludwiczak, Mohamed, Maftouh, Claudine, Picard, Bernard, Scatton, Gerard, Le Fur
Publikováno v:
The European journal of neuroscience. 26(12)
In the present study, we examined the occurrence and potential regulation of endocannabinoid release by cannabinoid CB1 receptors in the rat brain. To this end, we developed a highly sensitive (limit of sensitivity 30-300 amol) new analytical method,
Publikováno v:
The Journal of biological chemistry. 278(26)
In the present study, we observed evidence of cross-talk between the cannabinoid receptor CB1 and the orexin 1 receptor (OX1R) using a heterologous system. When the two receptors are co-expressed, we observed a major CB1-dependent enhancement of the
Autor:
Danielle, Gully, Michel, Geslin, Laurence, Serva, Evelyne, Fontaine, Pierre, Roger, Christine, Lair, Valerie, Darre, Claudine, Marcy, Pierre-Eric, Rouby, Jacques, Simiand, Josette, Guitard, Georgette, Gout, Regis, Steinberg, Daniel, Rodier, Guy, Griebel, Philippe, Soubrie, Marc, Pascal, Rebecca, Pruss, Bernard, Scatton, Jean-Pierre, Maffrand, Gerard, Le Fur
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 301(1)
4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1- (3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A), a new 2-aminothiazole derivative, shows nanomolar affinity for human cloned or nativ