Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Gerard L. Heck"'
Autor:
Jie Qian, Shobha Mummalaneni, Tam-Hao T Phan, Gerard L Heck, John A DeSimone, David West, Sunila Mahavadi, Deanna Hojati, Karnam S Murthy, Mee-Ra Rhyu, Andrew I Spielman, Mehmet Hakan Özdener, Vijay Lyall
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171335 (2017)
During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+ channels (ENaCs) in salt sensing fungiform (FF) taste receptor cells
Externí odkaz:
https://doaj.org/article/ea71b7d7bff144038341cb35f5fe30ed
Autor:
Shobha Mummalaneni, Jie Qian, Tam-Hao T Phan, Mee-Ra Rhyu, Gerard L Heck, John A DeSimone, Vijay Lyall
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98049 (2014)
The effects of small molecule ENaC activators N,N,N-trimethyl-2-((4-methyl-2-((4-methyl-1H-indol-3-yl)thio)pentanoyl)oxy)ethanaminium iodide (Compound 1) and N-(2-hydroxyethyl)-4-methyl-2-((4-methyl-1H-indol-3-yl)thio)pentanamide (Compound 2), were t
Externí odkaz:
https://doaj.org/article/32c4f55e43c246a8852849316ba0dab3
Publikováno v:
Chemical Senses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2db54997f2638a677ab57a15fc5e6121
https://doi.org/10.1201/9781003210146-3
https://doi.org/10.1201/9781003210146-3
Publikováno v:
Ultramicroscopy. 135:105-112
High throughput transmission electron microscopy (TEM) is limited by the time that it takes to prepare each specimen and insert it on the microscope. It is further impeded by the deteriorating vacuum of the microscope upon frequent specimen cycling.
Autor:
Tam-Hao T. Phan, Gerard L. Heck, Vijay Lyall, Shobha Mummalaneni, John A. DeSimone, ZuoJun Ren
Publikováno v:
Journal of Neurophysiology. 108:3206-3220
The relationship between taste receptor cell (TRC) Ca2+ concentration ([Ca2+]i) and rat chorda tympani (CT) nerve responses to salty [NaCl and NaCl+benzamil (Bz)] and sour (HCl, CO2, and acetic acid) taste stimuli was investigated before and after li
Autor:
Mehmet Hakan Ozdener, Vijay Lyall, Deanna Hojati, Karnam S. Murthy, Gerard L. Heck, David West, Jie Qian, Sunila Mahavadi, Andrew I. Spielman, Shobha Mummalaneni, Mee Ra Rhyu, Tam Hao T. Phan, John A. DeSimone
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0171335 (2017)
PLoS ONE, Vol 12, Iss 2, p e0171335 (2017)
During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+ channels (ENaCs) in salt sensing fungiform (FF) taste receptor cells
Autor:
Pamela Melone, Shobha Mummalaneni, Jamison Coleman, Gerard L. Heck, Vijay Lyall, ZuoJun Ren, Tam-Hao T. Phan, John A. DeSimone
Publikováno v:
Chemical Senses. 36:389-403
To investigate if chorda tympani (CT) taste nerve responses to strong (HCl) and weak (CO(2) and acetic acid) acidic stimuli are dependent upon NADPH oxidase-linked and cAMP-sensitive proton conductances in taste cell membranes, CT responses were moni
Publikováno v:
Chemical Senses. 34:373-382
We have demonstrated in humans that Na(+) evokes changes in the lingual surface potential (LSP) using a custom chamber. To assess whether a relationship exists between the Na(+)-evoked changes in the LSP and the intensity of salt taste, we measured t
Autor:
Vijay Lyall, Tam-Hao T. Phan, Gerd Kobal, John A. DeSimone, Shobha Mummalaneni, Mahdis Mansouri, Gerard L. Heck
Publikováno v:
Journal of Neurophysiology. 98:1662-1674
The effect of nicotine on the benzamil (Bz)-insensitive (transient receptor potential vanilloid-1 variant cation channel, TRPV1t) and the Bz-sensitive (epithelial Na+ channel, ENaC) salt taste receptors and sour taste was investigated by monitoring i
Autor:
Mee-Ra Rhyu, Gerard L. Heck, Vijay Lyall, John A. DeSimone, Shobha Mummalaneni, Tam-Hao T. Phan
Publikováno v:
Chemical senses. 40(6)
Modulatory effects of pHi and [Ca(2+)]i on taste receptor cell (TRC) epithelial sodium channel (ENaC) were investigated by monitoring chorda tympani (CT) responses to NaCl and KCl at various lingual voltages, before and after lingual application of i