Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gerard J.P. Van Westen"'
Autor:
Evan E. Bolton, Haralambos Sarimveis, Egon L. Willighagen, Hervé Ménager, Susanna-Assunta Sansone, Nina Jeliazkova, Antony J. Williams, Sirarat Sarntivijai, Emma L. Schymanski, Rob Stierum, Karel Berka, Pascal Kahlem, Jos Bessems, Pavel Babica, Montserrat Cases, Ludek Blaha, Hristo Aladjov, Reza Aalizadeh, Karine Audouze, Kasia Arturi, Alasdair Gray, Roland Grafström, Daan P. Geerke, Henner Hollert, Ola Spjuth, John M. Hancock, Kirtan Dave, Dimitrios Ε. Damalas, Thomas Exner, Marco Dilger, Boï Kone, Todor Kondic, Uko Maran, Steffen Neumann, Iseult Lynch, Fabien Jourdan, Philippe Rocca-Serra, Ferran Sanz, Danyel Jennen, Jos Kleinjans, Jana Klanova, Reza M. Salek, Sylvie Remy, Tobias Schulze, Brett Sallach, Penny Nymark, Sergio Martinez Cuesta, Noelia Ramirez, Herbert Oberacher, Craig E. Wheelock, Gerard J.P. van Westen, Barbara Zdrazil, Hilda Witters, Jonathan Tedds, Marvin Martens, Jaroslav Slobodnik, Ralf J.M. Weber, Nikolaos Thomaidis, Anže Županič, Chris T. Evelo
Publikováno v:
F1000Research, Vol 10 (2023)
Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-speci
Externí odkaz:
https://doaj.org/article/e59322df245a4fc28be0854e2252ef78
Autor:
Tareq B. Malas, Wouter N. Leonhard, Hester Bange, Zoraide Granchi, Kristina M. Hettne, Gerard J.P. Van Westen, Leo S. Price, Peter A.C. 't Hoen, Dorien J.M. Peters
Publikováno v:
EBioMedicine, Vol 51, Iss , Pp - (2020)
Background: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is one of the most common causes of end-stage renal failure, caused by mutations in PKD1 or PKD2 genes. Tolvaptan, the only drug approved for ADPKD treatment, results in serious side-ef
Externí odkaz:
https://doaj.org/article/233fc8102f9c4f019ed65089bafe6307
Autor:
Marina Gorostiola González, Remco L. van den Broek, Thomas G.M. Braun, Magdalini Chatzopoulou, Willem Jespers, Adriaan P. IJzerman, Laura H. Heitman, Gerard J.P. van Westen
Proteochemometric (PCM) modelling is a powerful computational drug discovery tool used in bioactivity prediction of potential drug candidates relying on both chemical and protein information. In PCM features are computed to describe small molecules a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48815af3fb6cb4d8a67d679ca410b30c
https://doi.org/10.26434/chemrxiv-2023-90082
https://doi.org/10.26434/chemrxiv-2023-90082
Autor:
Martin Sicho, Sohvi Luukkonen, Helle W. van den Maagdenberg, Linde Schoenmaker, Olivier J.M. Béquignon, Gerard J.P. van Westen
The discovery of novel molecules with desirable properties is a classic challenge in medicinal chemistry. With the recent advancements of machine learning, there has been a surge of de novo drug design tools. However, few resources exist that are bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::758128bdfb3fd73de18cd9363116f6ab
https://doi.org/10.26434/chemrxiv-2023-spz0g-v2
https://doi.org/10.26434/chemrxiv-2023-spz0g-v2
Autor:
Hein E.C. van der Wall, Gert-Jan Hassing, Robert-Jan Doll, Gerard J.P. van Westen, Adam F. Cohen, Jasper L. Selder, Michiel Kemme, Jacobus Burggraaf, Pim Gal
Publikováno v:
van der Wall, H E C, Hassing, G-J, Doll, R-J, van Westen, G J P, Cohen, A F, Selder, J L, Kemme, M, Burggraaf, J & Gal, P 2022, ' Cardiac age detected by machine learning applied to the surface ECG of healthy subjects : Creation of a benchmark ', Journal of Electrocardiology, vol. 72, pp. 49-55 . https://doi.org/10.1016/j.jelectrocard.2022.03.001
Journal of Electrocardiology, 72, 49-55
Journal of Electrocardiology, 72, 49-55. Churchill Livingstone
Journal of Electrocardiology, 72, 49-55
Journal of Electrocardiology, 72, 49-55. Churchill Livingstone
ObjectiveThe aim of the present study was to develop a neural network to characterize the effect of aging on the ECG in healthy volunteers. Moreover, the impact of the various ECG features on aging was evaluated.Methods & resultsA total of 6228 healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779640398559231932119e59ea21b8cc
https://research.vumc.nl/en/publications/5b8aa767-9e2a-479e-bbff-ce518ae65d81
https://research.vumc.nl/en/publications/5b8aa767-9e2a-479e-bbff-ce518ae65d81
Autor:
Noelia Ramirez, Iseult Lynch, Nikolaos S. Thomaidis, Ralf J. M. Weber, Hilda Witters, Evan E Bolton, Antony Williams, Pavel Babica, Susanna-Assunta Sansone, Kasia Arturi, Anže Županič, Gerard J.P. van Westen, Karine Audouze, Sergio Martinez Cuesta, Tobias Schulze, Jos Bessems, Dimitrios Damalas, Montserrat Cases, Penny Nymark, Ferran Sanz, Uko Maran, Haralambos Sarimveis, Ludek Blaha, Jaroslav Slobodnik, Jos C. S. Kleinjans, Todor Kondic, Hristo Aladjov, Egon Willighagen, Hervé Ménager, Brett Sallach, Danyel Jennen, Sirarat Sarntivijai, Roland C. Grafström, Rob Stierum, Jonathan Tedds, John M. Hancock, Reza M. Salek, Boï Kone, Karel Berka, Herbert Oberacher, Craig E. Wheelock, Steffen Neumann, Alasdair J. G. Gray, Pascal Kahlem, Sylvie Remy, Emma L. Schymanski, Marco Dilger, Ola Spjuth, Barbara Zdrazil, Marvin Martens, Kirtan Dave, Jana Klánová, Henner Hollert, Daan P. Geerke, Philippe Rocca-Serra, Nina Jeliazkova, Thomas Exner, Chris T. Evelo, Fabien Jourdan, Reza Aalizadeh
Publikováno v:
F1000Research
F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩
F1000Research, 10:1129. F1000 Research Ltd
F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩
F1000Research, 10:1129. F1000 Research Ltd
International audience; Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfb35debcfa39b9d8a61ded7efa15ea
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-485906
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-485906