Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Gerard J Davis"'
Autor:
Michael B Bass, Bin Yao, Yong-Jiang Hei, Yining Ye, Gerard J Davis, Michael T Davis, Barbara A Kaesdorf, Sabrina S Chan, Scott D Patterson
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108048 (2014)
We sought to develop placental growth factor as a predictive pharmacodynamic biomarker for motesanib efficacy as first-line therapy in patients with advanced nonsquamous non-small-cell lung cancer.Placental growth factor was evaluated at baseline and
Externí odkaz:
https://doaj.org/article/d3ebf97e97f0499b9c74773db40ee917
Autor:
Philip M. Hemken, Lori J. Sokoll, Xiaoqing Yang, Jianliang Dai, Debra Elliott, Susan H. Gawel, Michael Lucht, Ziding Feng, Jorge A. Marrero, Sudhir Srivastava, Daniel W. Chan, Gerard J. Davis
Publikováno v:
Clinical Proteomics, Vol 16, Iss 1, Pp 1-9 (2019)
Abstract Background The biomarkers alpha-fetoprotein (AFP) and protein induced by vitamin K absence/antagonist-II (PIVKA-II) may be useful for detecting early-stage hepatocellular carcinoma (HCC). We evaluated the performance of AFP and PIVKA-II leve
Externí odkaz:
https://doaj.org/article/6372f78b92604ff69a57ff25b809e583
Autor:
Shawn M. Sweeney, Hisham K. Hamadeh, Natalie Abrams, Stacey J. Adam, Sara Brenner, Dana E. Connors, Gerard J. Davis, Louis Fiore, Susan H. Gawel, Robert L. Grossman, Sean E. Hanlon, Karl Hsu, Gary J. Kelloff, Ilan R. Kirsch, Bill Louv, Deven McGraw, Frank Meng, Daniel Milgram, Robert S. Miller, Emily Morgan, Lata Mukundan, Thomas O'Brien, Paul Robbins, Eric H. Rubin, Wendy S. Rubinstein, Liz Salmi, Teilo Schaller, George Shi, Caroline C. Sigman, Sudhir Srivastava
Publikováno v:
Cancer Research. 83:1175-1182
Big data in healthcare can enable unprecedented understanding of diseases and their treatment, particularly in oncology. These data may include electronic health records, medical imaging, genomic sequencing, payor records, and data from pharmaceutica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71f4d3e129a9c64d20c7837ca7bd3bb5
https://doi.org/10.1158/0008-5472.can-22-1274
https://doi.org/10.1158/0008-5472.can-22-1274
Autor:
Shawn M. Sweeney, Hisham K. Hamadeh, Natalie Abrams, Stacey J. Adam, Sara Brenner, Dana E. Connors, Gerard J. Davis, Louis D. Fiore, Susan H. Gawel, Robert L. Grossman, Sean E. Hanlon, Karl Hsu, Gary J. Kelloff, Ilan R. Kirsch, Bill Louv, Deven McGraw, Frank Meng, Daniel Milgram, Robert S. Miller, Emily Morgan, Lata Mukundan, Thomas O'Brien, Paul Robbins, Eric H. Rubin, Wendy S. Rubinstein, Liz Salmi, Teilo H. Schaller, George Shi, Caroline C. Sigman, Sudhir Srivastava
Publikováno v:
Cancer Research. 83:1183-1190
The analysis of big healthcare data has enormous potential as a tool for advancing oncology drug development and patient treatment, particularly in the context of precision medicine. However, there are challenges in organizing, sharing, integrating,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9042c740550e4c3e4949faea3069c247
https://doi.org/10.1158/0008-5472.can-22-1277
https://doi.org/10.1158/0008-5472.can-22-1277
Autor:
Philip M. Hemken, Nicolette M. Jeanblanc, Tracey Rae, Susan E. Brophy, Maria J. Datwyler, Ying Xu, T. Scott Manetz, Inna Vainshtein, Meina Liang, Xiaodong Xiao, Partha S. Chowdhury, Chien-ying Chang, Katie Streicher, Lydia Greenlees, Koustubh Ranade, Gerard J. Davis
Publikováno v:
Practical Laboratory Medicine, Vol 9, Iss , Pp 58-68 (2017)
Background: Dipeptidyl peptidase-4 (DPP-4) may be a suitable biomarker to identify people with severe asthma who have greater activation of the interleukin-13 (IL-13) pathway and may therefore benefit from IL-13-targeted treatments. We report the ana
Externí odkaz:
https://doaj.org/article/b5d2f2e9efc14bc1853381f654d6d33b
Autor:
Nicolette Jeanblanc, Laurel Jackson, Susan Gawel, Susan Brophy, Shyam Vaidya, Salman Syed, Gerard J Davis, Jeffrey A. Borgia
Publikováno v:
Clinica Chimica Acta. 535:197-202
Early detection of lung cancer allows for earlier stage treatment initiation and improved patient prognosis. This report focuses on utilization of combining patient demographic information with non-invasive biomarkers and their potential ability to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988c433c2d9a708f72e7e598f375f829
https://doi.org/10.1016/j.cca.2022.09.003
https://doi.org/10.1016/j.cca.2022.09.003
Autor:
Jakob Kleif, Lars Nannestad Jørgensen, Jakob W. Hendel, Mogens R. Madsen, Jesper Vilandt, Søren Brandsborg, Lars Maagaard Andersen, Ali Khalid, Peter Ingeholm, Linnea Ferm, Gerard J. Davis, Susan H. Gawel, Frans Martens, Berit Andersen, Morten Rasmussen, Ib Jarle Christensen, Hans Jørgen Nielsen
Publikováno v:
Kleif, J, Jørgensen, L N, Hendel, J W, Madsen, M R, Vilandt, J, Brandsborg, S, Andersen, L M, Khalid, A, Ingeholm, P, Ferm, L, Davis, G J, Gawel, S H, Martens, F, Andersen, B, Rasmussen, M, Christensen, I J & Nielsen, H J 2022, ' Early detection of colorectal neoplasia : application of a blood-based serological protein test on subjects undergoing population-based screening ', British Journal of Cancer, vol. 126, no. 10, pp. 1387-1393 . https://doi.org/10.1038/s41416-022-01712-x
Br J Cancer
Br J Cancer
Background: Blood-based biomarkers used for colorectal cancer screening need to be developed and validated in appropriate screening populations. We aimed to develop a cancer-associated protein biomarker test for the detection of colorectal cancer in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282d0ec78d20951424b14312408e279b
https://doi.org/10.1038/s41416-022-01712-x
https://doi.org/10.1038/s41416-022-01712-x
Autor:
Philip M. Hemken, Eitan Israeli, Russell Taylor, Chris Jacobson, Maria Datwyler, Rene Geissler, Abbas Hadji, Nicolette Jeanblanc, Kinnari Pandya, Marilee Marcinkus, Ryan Piktel, M. Felicia Bogdan, Mary Rodgers, Mark Anderson, Robert Ziemann, Bryan C. Tieman, David Hawksworth, Jeffrey Moore, Kathy S. Otis, Christopher C. Marohnic, Josie Corby, Bailin Tu, Zhihong Lin, Alak Kar, James Hartnett, Carolyn Strobel, Svetoslava Gregory, Tracey Rae, A. Scott Muerhoff, Susan Brophy, John R. Hackett, David Daghfal, Matthew L. Faron, Amorina Cruz, Phaedre Mohr, Lori Sokoll, Gerard J. Davis
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM).
Objectives To evaluate pre-analytical challenges related to high-volume central laboratory SARS-CoV-2 antigen testing with a prototype qualitative SARS-CoV-2 antigen immunoassay run on the automated Abbott ARCHITECT instrument. Methods Contrived posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef77c7cbcadb3bc22d74725735a8a3d
https://doi.org/10.1515/cclm-2022-1292
https://doi.org/10.1515/cclm-2022-1292
Autor:
Hannah N. Marmor, Laurel Jackson, Susan Gawel, Michael Kammer, Pierre P. Massion, Eric L. Grogan, Gerard J. Davis, Stephen A. Deppen
Publikováno v:
Clin Chim Acta
BACKGROUND: Non-invasive biomarkers are needed to improve management of indeterminate pulmonary nodules (IPNs) suspicious for lung cancer. METHODS: Protein biomarkers were quantified in serum samples from patients with 6–30 mm IPNs (n=338). A previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b15580a581ad9a0f263d2b6e6ad215
https://europepmc.org/articles/PMC10057862/
https://europepmc.org/articles/PMC10057862/
Autor:
Sarah Østrup Jensen, Paul D. Lampe, Robert S. Bresalier, Linnea Ferm, Gerard J. Davis, Jon Ladd, Christina Demuth, Ib Jarle Christensen, Claus L. Andersen, Mathias M. Petersen, Hans Jørgen Nielsen, Niels Lech Pedersen
Publikováno v:
Clin Chim Acta
Lech Pedersen, N, Mertz Petersen, M, Ladd, J J, Lampe, P D, Bresalier, R S, Davis, G J, Demuth, C, Jensen, S, Andersen, C L, Ferm, L, Christensen, I J & Nielsen, H J 2020, ' Development of blood-based biomarker tests for early detection of colorectal neoplasia : Influence of blood collection timing and handling procedures ', Clinica Chimica Acta, vol. 507, pp. 39-53 . https://doi.org/10.1016/j.cca.2020.03.035
Lech Pedersen, N, Mertz Petersen, M, Ladd, J J, Lampe, P D, Bresalier, R S, Davis, G J, Demuth, C, Jensen, S, Andersen, C L, Ferm, L, Christensen, I J & Nielsen, H J 2020, ' Development of blood-based biomarker tests for early detection of colorectal neoplasia : Influence of blood collection timing and handling procedures ', Clinica Chimica Acta, vol. 507, pp. 39-53 . https://doi.org/10.1016/j.cca.2020.03.035
Introduction Blood-based, cancer-associated biomarkers are susceptible to a variety of well-known preanalytical factors. The influence of bowel preparation before a diagnostic colonoscopy on biomarker levels is, however, poorly investigated. The pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef4736ff5ac3d263ee37e97a09dc6c6
https://doi.org/10.1016/j.cca.2020.03.035
https://doi.org/10.1016/j.cca.2020.03.035