Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Gerard G. M. D'Souza"'
Autor:
Parul, Benien, Mohammed, Almuteri, Shrey, Shah, Mark, Böhlke, Ahmed, Mehanna, Gerard G M, D'Souza
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2275
Surface modification of liposomes with a ligand is facilitated by the conjugation of the ligand to a hydrophobic molecule that serves to anchor the ligand to the liposomal bilayer. We describe here a simple protocol to conjugate a triphenylphosphoniu
Autor:
Gerard G M D'Souza, Mark Böhlke, Ahmed S. Mehanna, Shrey Shah, Parul Benien, Mohammed Almuteri
Publikováno v:
Methods in Molecular Biology ISBN: 9781071612613
Methods in Molecular Biology
Methods in Molecular Biology ISBN: 9781493922871
Methods in Molecular Biology
Methods in Molecular Biology ISBN: 9781493922871
Surface modification of liposomes with a ligand is facilitated by the conjugation of the ligand to a hydrophobic molecule that serves to anchor the ligand to the liposomal bilayer. We describe here a simple protocol to conjugate a triphenylphosphoniu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d511fbc3e7edddb8444e263992290301
https://doi.org/10.1007/978-1-0716-1262-0_7
https://doi.org/10.1007/978-1-0716-1262-0_7
Publikováno v:
Methods in Molecular Biology ISBN: 9781071612613
DQAsomes (dequalinium-based liposome-like vesicles) are the prototype for all mitochondria-targeted vesicular pharmaceutical nanocarrier systems. First described in 1998 in a paper which has been cited as of May 2020 over 150 times, DQAsomes have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d22ce0d1f2733780a59684dda100f3
https://doi.org/10.1007/978-1-0716-1262-0_2
https://doi.org/10.1007/978-1-0716-1262-0_2
Publikováno v:
4open. 5:6
Introduction: The triphenyl phosphonium residue is a well-documented mitochondriotropic that has been shown to improve the accumulation of biomolecules in mitochondria. Stearyl triphenyl phosphonium (STPP) modified liposomes have been shown to facili
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2000
Tumor cells grown as spheroids more closely resemble in vivo solid tumors and present physical and physiological barriers to drug action that conventional monolayer cell cultures do not. The physiological relevance of the model can be further increas
Publikováno v:
Pharmaceutical Nanotechnology ISBN: 9781493995158
Tumor cells grown as spheroids more closely resemble in vivo solid tumors and present physical and physiological barriers to drug action that conventional monolayer cell cultures do not. The physiological relevance of the model can be further increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30445de37ac9fcb046b987d0a7a69c38
https://doi.org/10.1007/978-1-4939-9516-5_24
https://doi.org/10.1007/978-1-4939-9516-5_24
Publikováno v:
Cell Mol Bioeng
Nanomechanical investigation with Atomic Force Microscope has revealed new details regarding various nanomechanical heterogeneities for cells that are embedded in extracellular matrix in Multicellular spheroidal culture. This investigation sheds new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386ed031526d891750e06ab0f15f0a7b
https://doi.org/10.1101/193516
https://doi.org/10.1101/193516
The nanomechanical properties of various biological and cellular surfaces are increasingly investigated with Scanning Probe Microscopy. Surface stiffness measurements are currently being used to define metastatic properties of various cancerous cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0d7af316d0f47180e182b0ac40efa7
https://doi.org/10.1101/189852
https://doi.org/10.1101/189852
Publikováno v:
Mitochondrion. 13:464-472
Paclitaxel loaded in liposomes modified with stearyl triphenyl phosphonium (STPP) showed improved mitochondrial colocalization and cytotoxicity in a paclitaxel resistant cell line. The improvement in cytotoxicity was not solely due to the increased a
Autor:
Khaled A. Elsaid, Gerard G M D'Souza, Lucas Antônio Miranda Ferreira, Jason T. Machan, A. Liang, T. Truong
Publikováno v:
Osteoarthritis and Cartilage. 21(2):377-384
SummaryObjectiveTo evaluate cartilage diffusion and isolated chondrocyte association of micelles and liposomes and to determine the effect of cell-penetrating peptide (CPP) surface functionalization and extracellular matrix depletion on chondrocyte a