Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Gerard G Hanna"'
Autor:
Gargi Kothari, Beverley Woon, Cameron J. Patrick, James Korte, Leonard Wee, Gerard G. Hanna, Tomas Kron, Nicholas Hardcastle, Shankar Siva
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Artificial intelligence and radiomics have the potential to revolutionise cancer prognostication and personalised treatment. Manual outlining of the tumour volume for extraction of radiomics features (RF) is a subjective process. This study
Externí odkaz:
https://doaj.org/article/86d841c3ccf344ba84f28798d2166f84
Autor:
Gerard M. Walls, Valentina Giacometti, Aditya Apte, Maria Thor, Conor McCann, Gerard G. Hanna, John O'Connor, Joseph O. Deasy, Alan R. Hounsell, Karl T. Butterworth, Aidan J. Cole, Suneil Jain, Conor K. McGarry
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 23, Iss , Pp 118-126 (2022)
Background: Emerging data suggest that dose-sparing several key cardiac regions is prognostically beneficial in lung cancer radiotherapy. The cardiac substructures are challenging to contour due to their complex geometry, poor soft tissue definition
Externí odkaz:
https://doaj.org/article/4cb96ab78c3c42538d979ff36e9a946e
Autor:
Christian Wichmann, Sagun Parakh, Gerard G Hanna, Thomas John, Jason Callahan, Benjamin Blyth, Michael MacManus, Daniel Steinfort, Andrew M Scott, Lisa Devereux, Fiona Hegi-Johnson, Stacey E Rudd, Tim Akhurst, Peter Roselt, Jenny Trinh, Paul S Donnelly, Rod Hicks, Stephen Fox, Kate Burbury
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Background ImmunoPET is a multicentre, single arm, phase 0–1 study that aims to establish if 89Zr-durvalumab PET/CT can be used to interrogate the expression of PD-L1 in larger, multicentre clinical trials.Methods The phase 0 study recruited 5 PD-L
Externí odkaz:
https://doaj.org/article/3ec7e11a980b4b738c6b1a546c955538
Autor:
Reem Alomran, Michelle White, Melissa Bruce, Mathias Bressel, Susan Roache, Lama Karroum, Gerard G. Hanna, Shankar Siva, Shom Goel, Steven David
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background The enhanced knowledge of cancer biology has led to considerable advancement in systemic therapy for advanced breast cancer. Recently, studies showed that cyclin-dependent kinase (CDK) 4/6 inhibitor, when added to endocrine therap
Externí odkaz:
https://doaj.org/article/338a7c14bf3442d7947a85779583333b
Autor:
Mathieu Gaudreault, David Chang, Nicholas Hardcastle, Price Jackson, Tomas Kron, Gerard G. Hanna, Michael S. Hofman, Shankar Siva
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundBiology-guided radiotherapy (BgRT) uses real-time functional imaging to guide radiation therapy treatment. Positron emission tomography (PET) tracers targeting prostate-specific membrane antigen (PSMA) are superior for prostate cancer detec
Externí odkaz:
https://doaj.org/article/da0da06996164ae88ef5f5b31bfec45f
Autor:
Gerard M. Walls, Jamie B. Oughton, Anthony J. Chalmers, Sarah Brown, Fiona Collinson, Martin D. Forster, Kevin N. Franks, Alexandra Gilbert, Gerard G. Hanna, Nicola Hannaway, Stephen Harrow, Tom Haswell, Crispin T. Hiley, Samantha Hinsley, Matthew Krebs, Geraldine Murden, Rachel Phillip, Anderson J. Ryan, Ahmed Salem, David Sebag-Montefoire, Paul Shaw, Chris J. Twelves, Katrina Walker, Robin J. Young, Corinne Faivre-Finn, Alastair Greystoke
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 25, Iss , Pp 61-66 (2020)
Lung cancer is the leading cause of cancer mortality worldwide and most patients are unsuitable for ‘gold standard’ treatment, which is concurrent chemoradiotherapy. CONCORDE is a platform study seeking to establish the toxicity profiles of multi
Externí odkaz:
https://doaj.org/article/18ea8996e30244118c8f0fb5dfce7ad3
Publikováno v:
BMC Medical Education, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background The last two decades have seen revolutionary developments in both radiotherapy technology and postgraduate medical training. Trainees are expected to attain competencies using a mix of experiential learning, formal postgraduate te
Externí odkaz:
https://doaj.org/article/c9e1e2cfc51842bfbeb586a5735d9a94
Autor:
Penelope Schofield, Anna Ugalde, Gerard G Hanna, Olinda Santin, Clare O’Callaghan, Sharnel Miriam Perera, Cassandra Beer, G Prue, Katherine Lane
Publikováno v:
BMJ Open, Vol 11, Iss 10 (2021)
Objective To gather preliminary qualitative data that will assist in the codesign and development of a new informational and supportive website to assist informal cancer carers in Australia.Design and setting Utilising a previously tested codesign pr
Externí odkaz:
https://doaj.org/article/b6b325160e6c49afa518bf4f22aab4a1
Autor:
Robert Rulach, FRCR, David Ball, MD, Kevin L.M. Chua, FRCR, Max Dahele, MBChB, PhD, Dirk De Ruysscher, PhD, Kevin Franks, FRCR, Daniel Gomez, MD, Matthias Guckenberger, MD, Gerard G. Hanna, PhD, Alexander V. Louie, MD, PhD, Drew Moghanaki, MD, MPH, David A. Palma, MD, PhD, Clive Peedell, FRCR, Ahmed Salem, PhD, Shankar Siva, PhD, Gregory M.M. Videtic, MDCM, FRCPC, FACR, FASTRO, Anthony J. Chalmers, PhD, Stephen Harrow, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 2, Pp 100653- (2021)
Purpose: Thoracic reirradiation for non-small cell lung cancer with curative intent is potentially associated with severe toxicity. There are limited prospective data on the best method to deliver this treatment. We sought to develop expert consensus
Externí odkaz:
https://doaj.org/article/8cf5918332a84759847d320c465b5b34
Autor:
Steven David, Gwo Ho, Daphne Day, Marion Harris, Jennifer Tan, Shom Goel, Gerard G. Hanna, Ranjana Srivastava, Gill Kruss, Lachlan McDowell, Michelle White
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100939- (2021)
Current first-line systemic treatment in most patients with metastatic hormone receptor-positive, HER-2 negative breast cancer is an aromatase inhibitor in combination with a cyclin dependant kinase (CDK) 4/6 inhibitor. Frequently, these patients req
Externí odkaz:
https://doaj.org/article/7d95fe7dcfc74a4ba56a3404e5209bde