Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gerard Duart"'
Autor:
Maria Jesús García-Murria, Gerard Duart, Brayan Grau, Elisabet Diaz-Beneitez, Dolores Rodríguez, Ismael Mingarro, Luis Martínez-Gil
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Viral analogs of B-cell lymphoma 2 (Bcl2), known as vBcl2s, control apoptosis by interacting with host pro- and anti-apoptotic members of the Bcl2 family. Here, García-Murria et al. report on transmembrane domains (TMDs) in the C-terminal hydrophobi
Externí odkaz:
https://doaj.org/article/a095ff7f2cb74e3786be3ecd772374a0
Publikováno v:
Molecular & Cellular Oncology, Vol 8, Iss 3 (2021)
Viral control of apoptosis occurs through the expression of viral encoded anti-apoptotic B-cell lymphoma 2 (BCL2) analogs. These proteins are thought to restrain apoptosis by interacting with cellular BCL2 family members. We identified that protein-p
Externí odkaz:
https://doaj.org/article/ee38483f627c4e60a415cb617edcb7ed
Autor:
Gerard Duart, Mª Jesús García-Murria, Brayan Grau, José M. Acosta-Cáceres, Luis Martínez-Gil, Ismael Mingarro
Publikováno v:
Open Biology, Vol 10, Iss 9 (2020)
Coronavirus E protein is a small membrane protein found in the virus envelope. Different coronavirus E proteins share striking biochemical and functional similarities, but sequence conservation is limited. In this report, we studied the E protein top
Externí odkaz:
https://doaj.org/article/eb2271fdff754538a484ab5b0155eceb
Autor:
Maria Jesús García-Murria, Gerard Duart, Brayan Grau, Elisabet Diaz-Beneitez, Dolores Rodríguez, Ismael Mingarro, Luis Martínez-Gil
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22797-7
Externí odkaz:
https://doaj.org/article/88cc9110c5034f4ebf8733bf4e4f2200
Autor:
María J. García-Murria, Neus Expósito-Domínguez, Gerard Duart, Ismael Mingarro, Luis Martinez-Gil
Publikováno v:
Viruses, Vol 11, Iss 3, p 229 (2019)
Fusion of viral and cellular membranes is a key step during the viral life cycle. Enveloped viruses trigger this process by means of specialized viral proteins expressed on their surface, the so-called viral fusion proteins. There are multiple assays
Externí odkaz:
https://doaj.org/article/e4136beb9e844df0a85298f17c56d1a3
Autor:
Gerard Duart, Assaf Elazar, Jonathan Y. Weinstein, Laura Gadea-Salom, Juan Ortiz-Mateu, Sarel J. Fleishman, Ismael Mingarro, Luis Martinez-Gil
Several methods have been developed to explore interactions among water-soluble proteins or regions of proteins. However, techniques to target transmembrane domains have not been examined thoroughly. Here we developed a novel computational approach t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bc37e38ead43374decc7510cf3fdf0
https://doi.org/10.1101/2022.11.09.515782
https://doi.org/10.1101/2022.11.09.515782
Publikováno v:
Journal of molecular biology. 434(5)
Salt bridges between negatively (D, E) and positively charged (K, R, H) amino acids play an important role in protein stabilization. This has a more prevalent effect in membrane proteins where polar amino acids are exposed to a very hydrophobic envir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f32f0f980fdc985639614653ced4cb
https://pubmed.ncbi.nlm.nih.gov/35093395
https://pubmed.ncbi.nlm.nih.gov/35093395
Publikováno v:
Biochimica et Biophysica Acta. Biomembranes
Single-spanning SARS-CoV-2 envelope (E) protein topology is a major determinant of protein quaternary structure and function. - Charged residues distribution in E protein sequences from highly pathogenic human coronaviruses (i.e., SARS-CoV, MERS-CoV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55078cb23a3ca0f2fc31066baeeb5944
https://pubmed.ncbi.nlm.nih.gov/33771486
https://pubmed.ncbi.nlm.nih.gov/33771486
Autor:
Vicente Andreu-Fernández, Matti Javanainen, Gerard Duart, Ismael Mingarro, Diego Leiva, Mar Orzáez, Fabio Lolicato, Waldemar Kulig, Estefanía Lucendo, Mónica Sancho
Publikováno v:
Proc Natl Acad Sci U S A
The Bcl-2 protein family comprises both proand antiapoptotic members that control the permeabilization of the mitochondrial outer membrane, a crucial step in the modulation of apoptosis. Recent research has demonstrated that the carboxyl-terminal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a960fda4eede5fb043cb7a82747e2029
http://hdl.handle.net/10138/329276
http://hdl.handle.net/10138/329276