Membrane binding controls ordered self-assembly of animal septins

Autor: Agata Szuba, Fouzia Bano, Gerard Castro-Linares, Francois Iv, Manos Mavrakis, Ralf P Richter, Aurélie Bertin, Gijsje H Koenderink

Publikováno v: eLife, Vol 10 (2021)

Septins are conserved cytoskeletal proteins that regulate cell cortex mechanics. The mechanisms of their interactions with the plasma membrane remain poorly understood. Here, we show by cell-free reconstitution that binding to flat lipid membranes re

Externí odkaz: https://doaj.org/article/3826cc62710c47248207cb9c6cf3745b

Septin-microtubule association via a motif unique to isoform 1 of septin 9 tunes stress fibers

Autor: Magda Rodrigues, Maxime Gomes, Jindřiška Leischner Fialová, Ali Badache, Alex Llewellyn, Francois, Danièle Salaün, Pascal Verdier-Pinard, Gijsje H. Koenderink, Yuxiang Liu, Mayssa Belhabib, Taro Tachibana, Gerard Castro Linares, Manos Mavrakis, Keisuke Asano, Mira Kuzmić, Daniel Isnardon

Publikováno v: Journal of Cell Science, 135(1)

Septins, a family of GTP-binding proteins that assemble into higher order structures, interface with the membrane, actin filaments and microtubules, and are thus important regulators of cytoarchitecture. Septin 9 (SEPT9), which is frequently overexpr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639d91a5b73db06478cbf478f31d39d4
http://resolver.tudelft.nl/uuid:cf35b74b-42ba-472c-978a-bef6b274d3a9

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Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms

Autor: Laurie Ramond, Carla Silva Martins, Stéphanie Cabantous, Gerard Castro-Linares, Jérôme Wenger, Francois, Aurélie Bertin, Feng-Ching Tsai, Cyntia Taveneau, Renaud Vincentelli, Koyomi Nakazawa, Luc Camoin, Stéphane Audebert, Alex Llewellyn, Aurélie Di Cicco, Manos Mavrakis, Pascale Barbier, Mayssa Belhabib, Pascal Verdier-Pinard, Gijsje H. Koenderink

Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2021, 134 (15), pp.jcs258484. ⟨10.1242/jcs.258484⟩
Journal of Cell Science, 2021, 134 (15), pp.jcs258484. ⟨10.1242/jcs.258484⟩
Journal of Cell Science, 134(15)

Septin GTP-binding proteins contribute essential biological functions that range from the establishment of cell polarity to animal tissue morphogenesis. Human septins in cells form hetero-octameric septin complexes containing the ubiquitously express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3470c9090885fb43ab13209ff605666b
https://hal.archives-ouvertes.fr/hal-03119193

Septin-microtubule association requires a MAP-like motif unique to Sept9 isoform 1 embedded into septin octamers

Autor: Pascal Verdier-Pinard, Gijsje H. Koenderink, Alex Llewellyn, Maxime Gomes, Keisuke Asano, Danièle Salaün, Taro Tachibana, Jindřiška Leischner Fialová, Yuxiang Liu, Gerard Castro Linares, Mira Kuzmić, Manos Mavrakis, Ali Badache, Francois, Mayssa Belhabib

Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, In press, ⟨10.1101/2021.04.06.438596⟩

Septins, a family of GTP-binding proteins assembling into higher order structures, interface with the membrane, actin filaments and microtubules, which positions them as important regulators of cytoarchitecture. Septin 9 (Sept9), which is frequently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388e18221a63183826708b01cf24c0a7
https://doi.org/10.1101/2021.04.06.438596