Zobrazeno 1 - 10
of 301
pro vyhledávání: '"Gerard B Nash"'
Autor:
Sahithi J Kuravi, Clara M Yates, Mark Foster, Paul Harrison, Jon Hazeldine, Peter Hampson, Chris Watson, Antonio Belli, Mark Midwinter, Gerard B Nash
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183640 (2017)
Extracellular vesicles (EV) released into the circulation after traumatic injury may influence complications. We thus evaluated the numbers of EV in plasma over 28 days after trauma and evaluated their pro-coagulant and inflammatory effects.37 patien
Externí odkaz:
https://doaj.org/article/6e7b03f6bf084ca5a97dbaf897cf9b7d
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155161 (2016)
Mesenchymal stromal cells (MSC) are tissue-resident stromal cells capable of modulating immune responses, including leukocyte recruitment by endothelial cells (EC). However, the comparative potency of MSC from different sources in suppressing recruit
Externí odkaz:
https://doaj.org/article/93f77d9aa85d4d10ba9c24e1a6d16f03
Autor:
Christine A Fiddler, Helen Parfrey, Andrew S Cowburn, Ding Luo, Gerard B Nash, Gillian Murphy, Edwin R Chilvers
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0160108 (2016)
Aminopeptidase N (CD13) is a widely expressed cell surface metallopeptidase involved in the migration of cancer and endothelial cells. Apart from our demonstration that CD13 modulates the efficacy of tumor necrosis factor-α-induced apoptosis in neut
Externí odkaz:
https://doaj.org/article/82265c23db2648bea5382b96c4e44413
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118593 (2015)
We investigated the changes in neutrophil phenotype and function after transendothelial migration, and the roles played by integrin receptors in their behaviour. Neutrophils were tracked microscopically as they migrated through endothelial cells into
Externí odkaz:
https://doaj.org/article/ca56a1a4c3cc422ab8b5435c409927db
Autor:
Rosemary A Bamford, Zheng-yun Zhao, Neil A Hotchin, Iain B Styles, Gerard B Nash, James H R Tucker, Roy Bicknell
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95097 (2014)
Förster resonance energy transfer (FRET) technology relies on the close proximity of two compatible fluorophores for energy transfer. Tagged (Cy3 and Cy5) complementary DNA strands forming a stable duplex and a doubly-tagged single strand were shown
Externí odkaz:
https://doaj.org/article/23aa865591bc45d09f4e17ec94de7e68
Autor:
Samantha P Tull, Clara M Yates, Benjamin H Maskrey, Valerie B O'Donnell, Jackie Madden, Robert F Grimble, Philip C Calder, Gerard B Nash, G Ed Rainger
Publikováno v:
PLoS Biology, Vol 7, Iss 8, p e1000177 (2009)
Inflammation is a physiological response to tissue trauma or infection, but leukocytes, which are the effector cells of the inflammatory process, have powerful tissue remodelling capabilities. Thus, to ensure their precise localisation, passage of le
Externí odkaz:
https://doaj.org/article/3cc2dec3ba3e44febac53d8c8cac11e7
Autor:
Myriam Chimen, Aigli Evryviadou, Clare L. Box, Matthew J. Harrison, Jon Hazeldine, Lea H. Dib, Sahithi J. Kuravi, Holly Payne, Joshua M.J. Price, Dean Kavanagh, Asif J. Iqbal, Sian Lax, Neena Kalia, Alex Brill, Steve G. Thomas, Antonio Belli, Nicholas Crombie, Rachel A. Adams, Shelley-Ann Evans, Hans Deckmyn, Janet M. Lord, Paul Harrison, Steve P. Watson, Gerard B. Nash, G. Ed Rainger
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Interactions between platelets, leukocytes and the vessel wall provide alternative pathological routes of thrombo-inflammatory leukocyte recruitment. We found that when platelets were activated by a range of agonists in whole blood, they shed platele
Externí odkaz:
https://doaj.org/article/148d3754311e4a4b82c8c3464dde2293
Publikováno v:
Platelets, Vol 29, Iss 5, Pp 486-495 (2018)
Lymphatic endothelial cells (LEC) express the transmembrane receptor podoplanin whose only known endogenous ligand CLEC-2 is found on platelets. Both podoplanin and CLEC-2 are required for normal lymphangiogenesis as mice lacking either protein devel
Externí odkaz:
https://doaj.org/article/f71a51329dab4254a3058207774d5838
Autor:
Lu-Gang Yu, Jonathan M. Rhodes, John Hilkens, Philip C. Stone, Gerard B. Nash, Xiuli Guo, Qicheng Zhao
Supplementary Figure 1 from Circulating Galectin-3 Promotes Metastasis by Modifying MUC1 Localization on Cancer Cell Surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97035fdfb8be7c5134673c1d2e61a2a0
https://doi.org/10.1158/0008-5472.22378190.v1
https://doi.org/10.1158/0008-5472.22378190.v1
Autor:
Lu-Gang Yu, Jonathan M. Rhodes, John Hilkens, Philip C. Stone, Gerard B. Nash, Xiuli Guo, Qicheng Zhao
Supplementary Figure 2 from Circulating Galectin-3 Promotes Metastasis by Modifying MUC1 Localization on Cancer Cell Surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5fe560eb3a7acb4354abf4bfb9e37e
https://doi.org/10.1158/0008-5472.22378187.v1
https://doi.org/10.1158/0008-5472.22378187.v1