Zobrazeno 1 - 10 of 301 pro vyhledávání: '"Gerard B, Nash"'
1
Akademický článek
The role of valve stiffness in the insurgence of deep vein thrombosis
Autor: Zoe Schofield, Hosam Alden Baksamawi, Joana Campos, Alessio Alexiadis, Gerard B. Nash, Alexander Brill, Daniele Vigolo
Publikováno v: Communications Materials, Vol 1, Iss 1, Pp 1-10 (2020)
Deep vein thrombosis is the clotting of blood in deep veins. Here, a microfluidic device containing flexible valves fabricated in-situ is used to investigate the effects of blood flow conditions and valve elasticity on thrombus formation, revealing t
Externí odkaz: https://doaj.org/article/a33767ed188743749eee00b8e91af6f0
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2
Akademický článek
Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation
Autor: Myriam Chimen, Aigli Evryviadou, Clare L. Box, Matthew J. Harrison, Jon Hazeldine, Lea H. Dib, Sahithi J. Kuravi, Holly Payne, Joshua M.J. Price, Dean Kavanagh, Asif J. Iqbal, Sian Lax, Neena Kalia, Alex Brill, Steve G. Thomas, Antonio Belli, Nicholas Crombie, Rachel A. Adams, Shelley-Ann Evans, Hans Deckmyn, Janet M. Lord, Paul Harrison, Steve P. Watson, Gerard B. Nash, G. Ed Rainger
Publikováno v: Haematologica, Vol 105, Iss 5 (2020)
Interactions between platelets, leukocytes and the vessel wall provide alternative pathological routes of thrombo-inflammatory leukocyte recruitment. We found that when platelets were activated by a range of agonists in whole blood, they shed platele
Externí odkaz: https://doaj.org/article/148d3754311e4a4b82c8c3464dde2293
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3
Akademický článek
Modulation of VEGF-induced migration and network formation by lymphatic endothelial cells: Roles of platelets and podoplanin
Autor: Stacey A. Langan, Leyre Navarro-Núñez, Steve P. Watson, Gerard B. Nash
Publikováno v: Platelets, Vol 29, Iss 5, Pp 486-495 (2018)
Lymphatic endothelial cells (LEC) express the transmembrane receptor podoplanin whose only known endogenous ligand CLEC-2 is found on platelets. Both podoplanin and CLEC-2 are required for normal lymphangiogenesis as mice lacking either protein devel
Externí odkaz: https://doaj.org/article/f71a51329dab4254a3058207774d5838
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9
Akademický článek
Changes in the pattern of plasma extracellular vesicles after severe trauma.
Autor: Sahithi J Kuravi, Clara M Yates, Mark Foster, Paul Harrison, Jon Hazeldine, Peter Hampson, Chris Watson, Antonio Belli, Mark Midwinter, Gerard B Nash
Publikováno v: PLoS ONE, Vol 12, Iss 8, p e0183640 (2017)
Extracellular vesicles (EV) released into the circulation after traumatic injury may influence complications. We thus evaluated the numbers of EV in plasma over 28 days after trauma and evaluated their pro-coagulant and inflammatory effects.37 patien
Externí odkaz: https://doaj.org/article/6e7b03f6bf084ca5a97dbaf897cf9b7d
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10
Akademický článek
Comparative Ability of Mesenchymal Stromal Cells from Different Tissues to Limit Neutrophil Recruitment to Inflamed Endothelium.
Autor: Hafsa Munir, Nguyet-Thin Luu, Lewis S C Clarke, Gerard B Nash, Helen M McGettrick
Publikováno v: PLoS ONE, Vol 11, Iss 5, p e0155161 (2016)
Mesenchymal stromal cells (MSC) are tissue-resident stromal cells capable of modulating immune responses, including leukocyte recruitment by endothelial cells (EC). However, the comparative potency of MSC from different sources in suppressing recruit
Externí odkaz: https://doaj.org/article/93f77d9aa85d4d10ba9c24e1a6d16f03
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