Zobrazeno 1 - 10
of 431
pro vyhledávání: '"Gerard, Dijkstra"'
Autor:
Guido Trentadue, Peter B. F. Mensink, Claudius Kruse, Bernward Reszel, Gursah Kats-Ugurlu, Tjasso Blokzijl, Jan Willem Haveman, Klaas Nico Faber, Gerard Dijkstra, Uvo M. Hölscher, Jeroen J. Kolkman, Gisbert Knichwitz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Intestinal preservation for transplantation is accompanied by hypoperfusion with long periods of ischemia with total blood cessation and absolute withdrawal of oxygen leading to structural damage. The application of intraluminal oxygen has b
Externí odkaz:
https://doaj.org/article/7738e6d875c24531bc39ed70faf54d08
Autor:
Sem Geertsema, Paul Geertsema, Lyanne M. Kieneker, Amaal E. Abdulle, Sacha la Bastide-van Gemert, Stephan J.L. Bakker, Robin P.F. Dullaart, Gerard Dijkstra, Ron T. Gansevoort, Klaas Nico Faber, Harry van Goor, Arno R. Bourgonje
Publikováno v:
Redox Biology, Vol 77, Iss , Pp 103408- (2024)
Background: Chronic Kidney Disease (CKD), is often detected late due to its asymptomatic nature in the early stage of the disease. Overproduction of reactive oxygen species contributes to various pathological processes through oxidative stress (OS),
Externí odkaz:
https://doaj.org/article/52210a27e2d548f083e62c515b0ee5bd
Autor:
Marc Gjern Weiss, Anne Marye de Jong, Helene Seegert, Niels Moeslund, Hanno Maassen, Camilla Schjalm, Eline de Boer, Henri Leuvenink, Tom Eirik Mollnes, Marco Eijken, Anna Krarup Keller, Gerard Dijkstra, Bente Jespersen, Søren Erik Pischke
Publikováno v:
Transplant International, Vol 37 (2024)
Organs obtained from brain dead donors can have suboptimal outcomes. Activation of the innate immune system and translocation of intestinal bacteria could be causative. Thirty two pigs were assigned to control, brain death (BD), BD + luminal intestin
Externí odkaz:
https://doaj.org/article/591bbe74d3ef46c2a58fbe1dcbcd991a
Autor:
Femke M. Prins, Iwan J. Hidding, Marjolein A.Y. Klaassen, Valerie Collij, Johannes P.D. Schultheiss, Werna T.C. Uniken Venema, Amber Bangma, Jurne B. Aardema, Bernadien H. Jansen, Wout G.N. Mares, Ben J.M. Witteman, Eleonora A.M. Festen, Gerard Dijkstra, Marijn C. Visschedijk, Herma H. Fidder, Arnau Vich Vila, Bas Oldenburg, Ranko Gacesa, Rinse K. Weersma
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Emerging evidence suggests the gut microbiome’s potential in predicting response to biologic treatments in patients with inflammatory bowel disease (IBD). In this prospective study, we aimed to predict treatment response to vedolizumab and ustekinu
Externí odkaz:
https://doaj.org/article/75c0bb382cf0416fa8df443a241eb914
Autor:
Shixian Hu, Arno R. Bourgonje, Ranko Gacesa, Bernadien H. Jansen, Johannes R. Björk, Amber Bangma, Iwan J. Hidding, Hendrik M. van Dullemen, Marijn C. Visschedijk, Klaas Nico Faber, Gerard Dijkstra, Hermie J. M. Harmsen, Eleonora A. M. Festen, Arnau Vich Vila, Lieke M. Spekhorst, Rinse K. Weersma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Disrupted host-microbe interactions at the mucosal level are key to the pathophysiology of IBD. This study aimed to comprehensively examine crosstalk between mucosal gene expression and microbiota in patients with IBD. To study tissue-specif
Externí odkaz:
https://doaj.org/article/7d585f4cd17d4027b8c1cce58bfea380
Autor:
Irene J. Schaafsma, MSc, Froukje J. Hoogenboom, MSc, Gerard Dijkstra, PhD, Jelmer R. Prins, PhD, Marijn C. Visschedijk, PhD
Publikováno v:
AJOG Global Reports, Vol 4, Iss 2, Pp 100333- (2024)
BACKGROUND: Pregnant women with active perianal Crohn's disease indicate a cesarean delivery according to the current European Crohn's and Colitis Organisation guidelines. This advice is based on the assumption that vaginal delivery leads to exacerba
Externí odkaz:
https://doaj.org/article/91ba7721ea9548f98c59647414028bbf
Autor:
Milou M ter Avest, Annelieke S M van Velthoven, Anne E M Speckens, Gerard Dijkstra, Martin Dresler, Carmen S Horjus, Tessa E H Römkens, Ellen M Witteman, Willemijn A van Dop, Quirine M Bredero, Loes H C Nissen, Marloes J Huijbers
Publikováno v:
BMC Psychology, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Background Many patients with Inflammatory Bowel Diseases (IBD) suffer from psychological distress, fatigue and sleep disturbances, which are associated with reduced quality of life (QoL) and increased societal costs. Only limited psychosoci
Externí odkaz:
https://doaj.org/article/a67c6fec72114e3ca5b68ac27a5e8251
Autor:
Andrea E van der Meulen-de Jong, Gerard Dijkstra, Zlatan Mujagic, Marjolijn Duijvestein, Rogier L Goetgebuer, Roberta Loveikyte
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Introduction Iron deficiency anaemia (IDA) is the most common systemic manifestation of inflammatory bowel disease (IBD) that has detrimental effects on quality of life (QoL) and disease outcomes. Iron deficiency (ID), with or without anaemia, poses
Externí odkaz:
https://doaj.org/article/469e9e2b6da24ccbae0dd7ae26c3e242
Autor:
Raphael R. Fagundes, Gabriela Bravo-Ruiseco, Shixian Hu, Sarah J. Kierans, Rinse K. Weersma, Cormac T. Taylor, Gerard Dijkstra, Hermie J. M. Harmsen, Klaas Nico Faber
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionIntestinal epithelial cells produce interleukin-18 (IL-18), a key factor in promoting epithelial barrier integrity. Here, we analyzed the potential role of gut bacteria and the hypoxia-inducible factor 1α (HIF1α) pathway in regulating m
Externí odkaz:
https://doaj.org/article/5f37fa2f42fd405ca3fe8ff2670a47dc
Autor:
Yuchen Yang, Li Wang, Ivonne Peugnet-González, Daniela Parada-Venegas, Gerard Dijkstra, Klaas Nico Faber
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The intestinal mucosa is constantly exposed to commensal microbes, opportunistic pathogens, toxins, luminal components and other environmental stimuli. The intestinal mucosa consists of multiple differentiated cellular and extracellular components th
Externí odkaz:
https://doaj.org/article/36d90ce8b1fd41398195cfcb5f9b360e