Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Geralyn G. DeGuzman"'
Autor:
Ulla M. Marzec, Stephen R. Hanson, Thomas E. Rawson, Mark Ultsch, Linda O. Elliott, Stuart Bunting, Maureen Beresini, Richard Goldsmith, David Banner, Daniel P. Sutherlin, Canio J. Refino, Dean R. Artis, Kirk Robarge, Charles Eigenbrot, Daniel Kirchhofer, Saloumeh Kadkhodayan, Olivero Alan G, John A. Flygare, Geralyn G. DeGuzman
Publikováno v:
Journal of Biological Chemistry. 280:9160-9169
The serine protease factor VIIa (FVIIa) in complex with its cellular cofactor tissue factor (TF) initiates the blood coagulation reactions. TF.FVIIa is also implicated in thrombosis-related disorders and constitutes an appealing therapeutic target fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3bde94402741ade5f76a9872bbf67
https://doi.org/10.1074/jbc.m409068200
https://doi.org/10.1074/jbc.m409068200
Publikováno v:
Pharmaceutical Research. 19:1753-1756
Angiogenesis plays a critical role in several physiologic and pathologic processes, particularly in tumor growth, invasion, and metastasis (1). New blood vessels provide tumors with nutrients necessary for growth and also remove metabolic waste from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9137f904d2bb5d286c7115cfc4ac28b
https://doi.org/10.1023/a:1020778001267
https://doi.org/10.1023/a:1020778001267
Autor:
Stanley E. Hansen, L Richardson, Nishit B. Modi, Thomas F. Zioncheck, Geralyn G. DeGuzman, Paul J. Godowski
Publikováno v:
Endocrinology. 134:1879-1887
Hepatocyte growth factor (HGF) is a pluripotent mitogen thought to be involved in liver regeneration. It is synthesized as a single chain promitogen and requires proteolytic processing to a two-chain heterodimeric form for biological activity. The ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248f4cac14191d401ca885d9c24d0d75
https://doi.org/10.1210/endo.134.4.8137756
https://doi.org/10.1210/endo.134.4.8137756
Publikováno v:
Pharmaceutical research. 19(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5cbac34f27c8d96307a725d5c4f0122
https://pubmed.ncbi.nlm.nih.gov/12458683
https://pubmed.ncbi.nlm.nih.gov/12458683
Autor:
Nicolas Pelletier, Ben-Quan Shen, Guo-Wei He, Hongkui Jin, Zhen Ren, Thomas F. Zioncheck, Renhui Yang, Annie K. Ogasawara, Geralyn G. DeGuzman, Stuart Bunting
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 39(3)
Vascular endothelial growth factor (VEGF) induces hypotension in normotensive subjects, which is considered to be a major side effect for treatment of ischemic diseases. However, the hypotensive effect of VEGF has not been investigated in the setting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5cfc4b9bc42407a8934e7b95a624c61
https://pubmed.ncbi.nlm.nih.gov/11897770
https://pubmed.ncbi.nlm.nih.gov/11897770