Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Geraline Trossi-Torres"'
Autor:
Raju Timsina, Preston Hazen, Geraline Trossi-Torres, Nawal K. Khadka, Navdeep Kalkat, Laxman Mainali
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1923 (2024)
α-Crystallin (αABc) is a major protein comprised of αA-crystallin (αAc) and αB-crystallin (αBc) that is found in the human eye lens and works as a molecular chaperone by preventing the aggregation of proteins and providing tolerance to stress.
Externí odkaz:
https://doaj.org/article/18a121cba872453793f63116ae26513d
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1936 (2024)
Eye lens α-crystallin has been shown to become increasingly membrane-bound with age and cataract formation; however, to our knowledge, no studies have investigated the membrane interactions of α-crystallin throughout the development of cataracts in
Externí odkaz:
https://doaj.org/article/1ffc6487d4de4340beed4d57ff22e53f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13600 (2023)
Several discoveries show that with age and cataract formation, β-crystallin binds with the lens membrane or associates with other lens proteins, which bind with the fiber cell plasma membrane, accompanied by light scattering and cataract formation.
Externí odkaz:
https://doaj.org/article/d6a4885ff2e64309984361187e401642
Publikováno v:
Membranes, Vol 12, Iss 5, p 455 (2022)
α-crystallin-membrane association increases with age and cataracts, with the primary association site of α-crystallin being phospholipids. However, it is unclear if phospholipids’ acyl chain length and degree of unsaturation influence α-crystall
Externí odkaz:
https://doaj.org/article/c10ca14532a04f899c285cd0f3efb35d
Autor:
Geraline Trossi-Torres
Cataract is the leading cause of blindness worldwide. The only treatment for cataracts is the surgical removal of the cataractous lens and the replacement of an intraocular lens. With less availability of treatment and low income, the visual damage c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4458d06cff3d80f833d6aa3a1a4c877f
https://doi.org/10.18122/td.2038.boisestate
https://doi.org/10.18122/td.2038.boisestate
Autor:
Raju Timsina, Geraline Trossi-Torres, Jackson Thieme, Matthew O'Dell, Nawal K. Khadka, Laxman Mainali
Publikováno v:
Curr Eye Res
PURPOSE: This research aims to probe the interaction of α-crystallin with a model of human, porcine, and mouse lens-lipid membranes. METHODS: Cholesterol/model of human lens-lipid (Chol/MHLL), cholesterol/model of porcine lens-lipid (Chol/MPLL), and
Autor:
Sahayra Martínez, Sharilyn Almodovar, Angely Ortiz-Rosado, Edu B Suárez-Martínez, Geraline Trossi-Torres, Valerie Rodriguez‐Irizarry, Eric Rodriguez-Lopez, Marinel Ocasio-Rivera, Frances Marin-Maldonado
Publikováno v:
Medicine
Asthma is a chronic inflammatory and multifactorial respiratory tract disease. It affects over 18 million adults and 6 million children in the USA with Puerto Ricans showing the highest prevalence (12%–19%). This airways illness can be triggered by
Autor:
Raju Timsina, Geraline Trossi-Torres, Jackson Thieme, Matthew O’Dell, Nawal Khadka, Laxman Mainali
Publikováno v:
Biophysical Journal. 121:79a
Publikováno v:
Biophysical Journal. 121:79a
Publikováno v:
Exp Eye Res
The concentration of α-crystallin decreases in the eye lens cytoplasm, with a corresponding increase in membrane-bound α-crystallin during cataract formation. The eye lens's fiber cell plasma membrane consists of extremely high cholesterol (Chol) c