The sickle cell trait and end stage renal disease in Salvador, Brazil.

Autor: Dona J Alladagbin, Paula N Fernandes, Maria B Tavares, Jean T Brito, Geraldo G S Oliveira, Luciano K Silva, Nadia A Khouri, Marilia B Oliveira, Tatiana Amorim, Cácia M Matos, Guilherme S Ribeiro, Antônio A Lopes, Marilda S Gonçalves, Washington L C Dos-Santos

Publikováno v: PLoS ONE, Vol 13, Iss 12, p e0209036 (2018)

BACKGROUND:Carriers of the sickle cell trait (HbAS) usually remain asymptomatic. However, under conditions of low tissue oxygenation, red blood cell sickling and vascular obstruction may develop. Chronic kidney disease (CKD) can arise from conditions

Externí odkaz: https://doaj.org/article/827ac5349c7a4824b3cc94e8e74eeed1

Disruption of Splenic Lymphoid Tissue and Plasmacytosis in Canine Visceral Leishmaniasis: Changes in Homing and Survival of Plasma Cells.

Autor: Joselli Silva-O'Hare, Isabela Silva de Oliveira, Thaís Klevorn, Valter A Almeida, Geraldo G S Oliveira, Ajax M Atta, Luiz Antonio R de Freitas, Washington L C Dos-Santos

Publikováno v: PLoS ONE, Vol 11, Iss 5, p e0156733 (2016)

Visceral leishmaniasis (VL) is a disease caused by Leishmania infantum, which is transmitted by phlebotomine sandflies. Dogs are the main urban reservoir of this parasite and the disease presents similar characteristics in both humans and dogs. In th

Externí odkaz: https://doaj.org/article/d9164e8757514efab9039c548d6ea3b9

Disorganization of spleen compartments and dermatitis in canine visceral leishmaniasis

Autor: Claudia C. Santana, Geraldo G. S. Oliveira, Washington Luis Conrado dosSantos, Luiz Antônio Rodrigues de Freitas

Publikováno v: Surgical and Experimental Pathology, Vol 2, Iss 1, Pp 1-8 (2019)

Canine visceral leishmaniasis is associated with splenic changes that may interfere with the surveillance of blood borne antigens. Dogs with terminal visceral leishmaniasis present with a variety of skin lesions that may reflect a failure of the immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69af71b77fe78d3b329a37c38371a5ba
http://link.springer.com/article/10.1186/s42047-019-0040-0

Collectins and galectins in the abomasum of goats susceptible and resistant to gastrointestinal nematode infection

Autor: Maria Angela Ornelas de Almeida, C. R. Madruga, Bárbara Maria Paraná da Silva Souza, Gustavo F. Saldaña, Geraldo G. S. Oliveira, Sabrina Mota Lambert, Sandra Mayumi Nishi, Luís da Silva Vieira

Publikováno v: Veterinary Parasitology: Regional Studies and Reports. 12:99-105

Originally described in cattle, conglutinin belongs to the collectin family and is involved in innate immune defense. It is thought that conglutinin provides the first line of defense by maintaining a symbiotic relationship with the microbes in the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba85be09e9a3c8e73327342ad36dc18b
https://doi.org/10.1016/j.vprsr.2017.12.001

Combined in vitro IL-12 and IL-15 stimulation promotes cellular immune response in dogs with visceral leishmaniasis

Autor: Catiule de Oliveira Santos, Valéria Marçal Felix de Lima, Marilene Oliveira dos Santos Maciel, Jaqueline Poleto Bragato, Geraldo G. S. Oliveira, Gabriela Lovizutto Venturin, Bárbara Maria Nascimento de Oliveira, Larissa Martins Melo, Sidnei Ferro Costa, Vinícius Oliveira Gomes, Gabriela Torres Rebech

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0008021 (2020)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Domestic dogs are the main reservoir of Leishmania infantum, a causative agent of visceral leishmaniasis (VL). The number of human disease cases is associated with the rate of canine infection. Currently available drugs are not efficient at treating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5cedceedf80a10b54ece018ca5309df
http://europepmc.org/articles/PMC7006941