Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Geraldine W.Y. Goh"'
Autor:
Liting Hang, Ziyin Wang, Aaron S.C. Foo, Geraldine W.Y. Goh, Huey Ching Choong, John Thundyil, Shengli Xu, Kong-Peng Lam, Kah-Leong Lim
Publikováno v:
Neurobiology of Disease, Vol 161, Iss , Pp 105560- (2021)
Emerging studies implicate energy dysregulation as an underlying trigger for Parkinson's disease (PD), suggesting that a better understanding of the molecular pathways governing energy homeostasis could help elucidate therapeutic targets for the dise
Externí odkaz:
https://doaj.org/article/e681f29124b6458790dfeedd53c81d8a
Autor:
John Thundyil, Aaron S. C. Foo, Geraldine W.Y. Goh, Liting Hang, Kah-Leong Lim, Huey Ching Choong, Kong-Peng Lam, Shengli Xu, Ziyin Wang
Publikováno v:
Neurobiology of Disease, Vol 161, Iss, Pp 105560-(2021)
Emerging studies implicate energy dysregulation as an underlying trigger for Parkinson's disease (PD), suggesting that a better understanding of the molecular pathways governing energy homeostasis could help elucidate therapeutic targets for the dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4297372e7d776455194ef70f69ffb7c8
https://hdl.handle.net/10356/160637
https://hdl.handle.net/10356/160637
Autor:
Liting Hang, Geraldine W.Y. Goh, Ziyin Wang, Huey Ching Choong, John Thundyil, Shengli Xu, Kong Peng Lam, Kah-Leong Lim
Emerging studies implicate energy dysregulation as an underlying trigger for Parkinson’s disease (PD), suggesting that a better understanding of the molecular pathways governing energy homeostasis could help elucidate therapeutic targets for the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f2780bae82848ad048e84ffde6c1bb3
https://doi.org/10.21203/rs.3.rs-43593/v1
https://doi.org/10.21203/rs.3.rs-43593/v1
Autor:
Chun-Hyung Kim, Hye Min Park, Xue-Wei Liu, Choong Hwan Lee, Bin Song, Sungwhan F. Oh, CongBao Kang, Sreekanth Rajan, Geraldine W.Y. Goh, Gregory A. Petsko, Aida Serra, Jeha Jeon, Hong Ye, Yongwoo Jang, Serap Beldar, Kah-Leong Lim, Woori Kim, Jun Yeob Yoo, Melissa Feitosa, Ho Sup Yoon, Dabin Hwang, Hui Ting Toh, Yeahan Kim, Kwang-Soo Kim, Julien Lescar
Publikováno v:
Nat Chem Biol
The orphan nuclear receptor Nurr1 is critical for the development, maintenance and protection of midbrain dopaminergic (mDA) neurons. Here we show that prostaglandin E1 (PGE1) and its dehydrated metabolite, PGA1, directly interact with the ligand-bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd588e0ced5ac7d9716ad1af8cedaca4
https://hdl.handle.net/10356/155280
https://hdl.handle.net/10356/155280
Publikováno v:
Neuromolecular Medicine
Parkinson's disease (PD) is a prevalent neurodegenerative movement disorder that is characterized pathologically by the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) of the midbrain. Despite intensive rese