Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Geraldine T. Petr"'
Autor:
Paul A. Rosenberg, Kathryn D. Fischer, Geraldine T. Petr, Eileen M. Denovan-Wright, Robert B. Laprairie, Yan Sun
GLT-1 is the major glutamate transporter in the brain, and is expressed in astrocytes and in axon terminals in the hippocampus, cortex, and striatum. Neuronal GLT-1 accounts for only 5–10% of total brain GLT-1 protein, and its function is uncertain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cf3be61601ae33f414d702425611c3
https://europepmc.org/articles/PMC6249114/
https://europepmc.org/articles/PMC6249114/
Autor:
Paul A. Rosenberg, Kayla C. Hussey, Laurel A. Schultheis, Janet M. Dubinsky, Geraldine T. Petr, Yan Sun, Chiye Aoki
Publikováno v:
European Journal of Neuroscience. 38:2477-2490
Excitotoxicity is thought to be important in the pathogenesis of Huntington’s disease (HD). Glutamate is the predominant excitatory neurotransmitter in the brain and excess activation of glutamate receptors can cause neuronal dysfunction and death.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b87f5fe7a16b38116cadf07ff25435
https://doi.org/10.1111/ejn.12202
https://doi.org/10.1111/ejn.12202
Autor:
Paul A. Rosenberg, Kathryn D. Fischer, Niels C. Danbolt, Clive Miranda, Wencke Armsen, Geraldine T. Petr, Yun Zhou, Natalie M. Frederick, Mustafa Q. Hameed, Edward A. Bedoya, Sameer C. Dhamne, Yan Sun, Alexander Rotenberg, Jianlin Wang, Chiye Aoki
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(13)
GLT-1 (EAAT2; slc1a2) is the major glutamate transporter in the brain, and is predominantly expressed in astrocytes, but at lower levels also in excitatory terminals. We generated a conditional GLT-1 knock-out mouse to uncover cell-type-specific func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265e5b9915f9b2b05fadcf7187e2dafd
https://pubmed.ncbi.nlm.nih.gov/25834045
https://pubmed.ncbi.nlm.nih.gov/25834045
Autor:
Natalie M. Frederick, Wencke Armsen, Geraldine T. Petr, Elias Aizenman, Paul A. Rosenberg, Ekaterina Bakradze, Jianlin Wang
Publikováno v:
Neurochemistry international. 62(7)
Excitotoxicity may contribute to the pathogenesis of Huntington’s disease. High affinity Na+ dependent glutamate transporters, residing in the plasma membrane, clear glutamate from the extracellular space and are the primary means of prevention aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a184f31af4a644ad3c7aad338243a5e6
https://pubmed.ncbi.nlm.nih.gov/23507328
https://pubmed.ncbi.nlm.nih.gov/23507328