Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Geraldine R. Rogers"'
Publikováno v:
Journal of Psychopharmacology. 24:1243-1251
Antidepressant drugs can exert significant effects on the mood of a patient suffering major depression and other disorders. These drugs generally have pharmacological actions on the uptake or metabolism of the neurotransmitters serotonin, noradrenali
Autor:
Elisabeth Wells, Roger T. Mulder, Martin A. Kennedy, Allison L. Miller, Melanie D. E. Allington, Peter R. Joyce, Douglas Sellman, Geraldine R. Rogers, Robin J. Olds
Publikováno v:
American Journal of Medical Genetics. :95-98
Novelty Seeking (NS) is a human personality trait in which impulsive, exploratory, and thrill-seeking behaviors are displayed. Dopaminergic genes have been prime candidates in the search for the genetic factors underlying NS because of the central ro
Autor:
Martin A. Kennedy, Roger T. Mulder, Janice M. McKenzie, Geraldine R. Rogers, Allison L. Miller, Peter R. Joyce, Suzanne E. Luty
Publikováno v:
The International Journal of Neuropsychopharmacology. 6:339-346
In 169 depressed patients randomized to treatment with either fluoxetine or nortriptyline, we examined whether polymorphisms of the serotonin transporter and the G protein beta3 subunit influenced response to these antidepressants. For depressed pati
Autor:
Geraldine R. Rogers, Martin A. Kennedy, Peter R. Joyce, Melanie D. E. Allington, Mark Hughes, Dylan M. Glubb, Patrick C McHugh
Publikováno v:
Acta neuropsychiatrica. 20(6)
Objective:The mechanism of action of antidepressant drugs is not fully understood. Application of genomic methods enables the identification of biochemical pathways that are regulated by antidepressants, and this may provide novel clues to the molecu
Autor:
David J. Hamrock, Peter M. Steinert, Lyuben N. Marekov, Vincenzo De Laurenzi, Geraldine R. Rogers, William B. Rizzo, Nelli Markova, John G. Compton
Publikováno v:
Nature Genetics. 12:52-57
Sjögren-Larsson syndrome (SLS) is an inherited neurocutaneous disorder characterized by mental retardation, spasticity and ichthyosis. SLS patients have a profound deficiency in fatty aldehyde dehydrogenase (FALDH) activity. We have now cloned the h
Autor:
Patrick C McHugh, Dylan M. Glubb, Geraldine R. Rogers, Peter R. Joyce, Martin A. Kennedy, Barbara Loudon
Publikováno v:
Journal of neuroscience research. 86(2)
Antidepressant drugs can have significant effects on the mood of a patient suffering from major depression or other disorders. The pharmacological actions of these drugs generally affect the uptake or metabolism of the neurotransmitters serotonin, no
Publikováno v:
Mammalian Genome. 8:938-940
Autor:
Peter R. Joyce, Martin A. Kennedy, Suzanne E. Luty, Roger T. Mulder, Allison L. Miller, Geraldine R. Rogers
Publikováno v:
Psychiatry research. 119(1-2)
We investigated whether polymorphisms of the dopamine D4 receptor (DRD4) and polymorphisms of the dopamine D3 receptor (DRD3) were associated with personality disorder symptomatology rather than with personality traits such as novelty seeking. DNA wa
Publikováno v:
Journal of cutaneous medicine and surgery. 3(1)
Background: Gorlin syndrome is an autosomal dominant disorder characterized by developmental defects and susceptibility to cancer, especially to basal cell carcinomas. The genetic basis of this disorder has recently been elucidated. Methods: In this
Autor:
Vincenzo De Laurenzi, Nedialka G. Markova, Geraldine R. Rogers, William B. Rizzo, John G. Compton
Publikováno v:
Genomics. 39(2)
Mutations in the fatty aldehyde dehydrogenase (FALDH) gene cause Sjogren-Larsson syndrome (SLS)-a disease characterized by mental retardation, spasticity, and congenital ichthyosis. To facilitate mutation analysis in SLS and to study the pathogenesis