Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Geraldine Pawlak"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45909 (2012)
Podosomes are dynamic actin-based structures found constitutively in cells of monocytic origin such as macrophages, dendritic cells and osteoclasts. They have been involved in osteoclast cell adhesion, motility and matrix degradation, and all these f
Externí odkaz:
https://doaj.org/article/6530db0eead1465bb93c25cf581b8bc8
Autor:
Geraldine Pawlak, David M. Helfman, S. Bruce Malkowicz, Raghunath Puthiyaveettil, John E. Tomaszewski, Trang B. Nguyen, Terence W. McGarvey
Publikováno v:
International Journal of Cancer. 110:368-373
Previous studies of transformed rodent fibroblasts have suggested that specific isoforms of the actin-binding protein tropomyosin (TM) could function as suppressors of transformation, but an analysis of TM expression in patient tumor tissue is limite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc80bcd75fe0bb3ff20ff58ed332f166
https://doi.org/10.1002/ijc.20151
https://doi.org/10.1002/ijc.20151
Autor:
David M. Helfman, Geraldine Pawlak
Publikováno v:
Journal of Biological Chemistry. 277:26927-26933
Cellular transformation by v-Src is believed to be caused by aberrant activation of signaling pathways that are normally regulated by cellular Src. Using normal rat kidney cells expressing a temperature-sensitive mutant of v-Src, we examined the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d608c42b234928c42fd5dbd97a6540
https://doi.org/10.1074/jbc.m202261200
https://doi.org/10.1074/jbc.m202261200
Autor:
David M. Helfman, Geraldine Pawlak
Publikováno v:
Journal of cellular biochemistry. 95(5)
The actin cytoskeleton is recognized as an important component of both adhesion- and growth factor-dependent signaling, but its role in oncogene-dependent signaling has received much less attention. In this study, we investigated the role played by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329fb0947cacd2e65142da37f1d9640e
https://pubmed.ncbi.nlm.nih.gov/15962288
https://pubmed.ncbi.nlm.nih.gov/15962288
Autor:
David M. Helfman, Geraldine Pawlak
Transformation by oncogenic Ras profoundly alters actin cytoskeleton organization. We investigated Ras-dependent signaling pathways involved in cytoskeleton disruption by transfecting normal rat kidney (NRK) cells with different Ras mutants. RasV12S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50881030e9d8db8738426504a313a309
https://europepmc.org/articles/PMC65092/
https://europepmc.org/articles/PMC65092/
Autor:
David M. Helfman, Geraldine Pawlak
Publikováno v:
Current opinion in geneticsdevelopment. 11(1)
Research during the past couple of years has provided important new information as to how the actin cytoskeleton contributes to growth control in both normal and transformed cells. The cytoskeleton can no longer be viewed as simply a structural frame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1c8fcc6472fd590eac0596c06422e0
https://pubmed.ncbi.nlm.nih.gov/11163149
https://pubmed.ncbi.nlm.nih.gov/11163149
Autor:
Geraldine, Pawlak, M, Helfman David
Publikováno v:
Molecular Biology of the Cell; January 2002, Vol. 13 Issue: 1 p336-47, 12p