Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Geraldine Longo"'
Autor:
Patrick W. Mantyh, Geraldine Longo, Stephane Chartier, Michelle N. Fealk, Lisa Majuta, Michelle L. Thompson, Gwen McCaffrey
Supplementary Figure 1. Patella displacement is a confounding factor in bone cancer pain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4339e2b70ef841ed739b538881d15cde
https://doi.org/10.1158/0008-5472.22403111.v1
https://doi.org/10.1158/0008-5472.22403111.v1
Autor:
Patrick W. Mantyh, Geraldine Longo, Stephane Chartier, Michelle N. Fealk, Lisa Majuta, Michelle L. Thompson, Gwen McCaffrey
This film depicts the spontaneous nocifensive behavior of a mouse at Day 17 post-cancer cell injection. Throughout the film there are several visual cues that are indicative of nocifensive behavior. The pronounced changes in behavior and movements of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd9dc3033d5eb7310609014f602e5e8
https://doi.org/10.1158/0008-5472.22403099.v1
https://doi.org/10.1158/0008-5472.22403099.v1
Autor:
Patrick W. Mantyh, Geraldine Longo, Stephane Chartier, Michelle N. Fealk, Lisa Majuta, Michelle L. Thompson, Gwen McCaffrey
This film depicts the nocifensive behavior of a naïve mouse. During the film, when the mouse is stationary, the toes of the left foot are spread out and a range of brightness appears on the bottom of the foot because it is bearing weight on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c95f5facc642f34099e63bd6a8dd7d9
https://doi.org/10.1158/0008-5472.22403105.v1
https://doi.org/10.1158/0008-5472.22403105.v1
Autor:
Patrick W. Mantyh, Geraldine Longo, Stephane Chartier, Michelle N. Fealk, Lisa Majuta, Michelle L. Thompson, Gwen McCaffrey
This file provides supplemental materials and methods, supplemental video legends, and supplemental material references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6670b67cad6fd76d02f057f994787843
https://doi.org/10.1158/0008-5472.22403114
https://doi.org/10.1158/0008-5472.22403114
Autor:
Michelle N. Fealk, Jean Marc G. Guedon, Lisa A. Majuta, Patrick W. Mantyh, Geraldine Longo, Michelle L. Thomspon
Publikováno v:
Pain. 157:1239-1247
Recent studies have suggested that in humans and animals with significant skeletal pain, changes in the mechanical hypersensitivity of the skin can be detected. However, whether measuring changes in skin hypersensitivity can be a reliable surrogate f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74d68ce3a004ff7d5fd7a0ef8d39fa5
https://doi.org/10.1097/j.pain.0000000000000514
https://doi.org/10.1097/j.pain.0000000000000514
Publikováno v:
Pain. 156:157-165
The number of patients suffering from postoperative pain due to orthopedic surgery and bone fracture is projected to dramatically increase because the human life span, weight, and involvement in high-activity sports continue to rise worldwide. Joint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce17f39347cae7fa7960bc79f2ebb5ea
https://doi.org/10.1016/j.pain.0000000000000017
https://doi.org/10.1016/j.pain.0000000000000017
Autor:
Philippe Séguéla, Geraldine Longo, Alfredo Ribeiro-da-Silva, Maria Zamfir, Steven Cordeiro Matos
Publikováno v:
Brain structurefunction. 223(3)
Functional changes in hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels have been shown to contribute to medial prefrontal (mPFC) hyperexcitability after peripheral nerve injury. A reduction in the open probability of these neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0711946c006d8b7e7fad88d000fd37b2
https://pubmed.ncbi.nlm.nih.gov/29094305
https://pubmed.ncbi.nlm.nih.gov/29094305
Autor:
Geraldine Longo, Lisa A. Majuta, Michelle N. Fealk, Stephane R. Chartier, Patrick W. Mantyh, Michelle L. Thompson, Gwen McCaffrey
Publikováno v:
Cancer Research. 74:7014-7023
Studies in animals and humans show that blockade of nerve growth factor (NGF) attenuates both malignant and nonmalignant skeletal pain. While reduction of pain is important, a largely unanswered question is what other benefits NGF blockade might conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8de3251e8fd0323f3a12dc801f07ccf
https://doi.org/10.1158/0008-5472.can-14-1220
https://doi.org/10.1158/0008-5472.can-14-1220
Autor:
Patrick W. Mantyh, Lisa A. Majuta, Michelle L. Thompson, Michelle N. Fealk, Geraldine Longo, Stephane R. Chartier
Publikováno v:
Pain. 155:2323-2336
Skeletal injury is a leading cause of chronic pain and long-term disability worldwide. While most acute skeletal pain can be effectively managed with nonsteroidal anti-inflammatory drugs and opiates, chronic skeletal pain is more difficult to control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d66c2d3c35bac9de34d9c1cd4b05914
https://doi.org/10.1016/j.pain.2014.08.026
https://doi.org/10.1016/j.pain.2014.08.026
Autor:
Alexander H. Tuttle, John N. Wood, Jeffrey S. Wieskopf, Ihab Daou, Ariel R. Ase, Philippe Séguéla, Jeffrey S. Mogil, Robert P. Bonin, Geraldine Longo, A. Ribeiro-da-Silva, Y. De Koninck
Publikováno v:
The Journal of Neuroscience. 33:18631-18640
We report a novel model in which remote activation of peripheral nociceptive pathways in transgenic mice is achieved optogenetically, without any external noxious stimulus or injury. Taking advantage of a binary genetic approach, we selectively targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866ab1b7c8c69ff42b93fdddc55ea1bd
https://doi.org/10.1523/jneurosci.2424-13.2013
https://doi.org/10.1523/jneurosci.2424-13.2013