Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Geraldine Descamps"'
Autor:
Benoit Tessoulin, Geraldine Descamps, Christelle Dousset, Martine Amiot, Catherine Pellat-Deceunynck
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Prima-1Met (APR-246) was previously shown to be dependent on glutathione inhibition and on ROS induction in cancer cells with mutated or deleted TP53. Because this ROS induction was, at least in part, due to a direct interference with the thioredoxin
Externí odkaz:
https://doaj.org/article/3bacdfcf8c9b4a4e916a25e68db322e7
Autor:
Romane Durand, Domitille Costes-Tertrais, Geraldine Descamps, Christelle Dousset, Sophie Maïga, Jean-Baptiste Alberge, Elise Douillard, Jennifer Derrien, Celine Bellanger, David Chiron, Stephane Minvielle, Cyrille Touzeau, Philippe Moreau, Martine Amiot, Patricia Gomez-Bougie, Agnes Moreau-Aubry, Catherine Pellat-Deceunynck
Publikováno v:
Blood. 140:4198-4199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68358fc5d38745cca0becedcd4afc4fe
https://doi.org/10.1182/blood-2022-155862
https://doi.org/10.1182/blood-2022-155862
Autor:
Romane Durand, Céline Bellanger, Géraldine Descamps, Christelle Dousset, Sophie Maïga, Jennifer Derrien, Laura Thirouard, Louise Bouard, Hélène Asnagli, Philip Beer, Andrew Parker, Patricia Gomez‐Bougie, Marie‐Claire Devilder, Philippe Moreau, Cyrille Touzeau, Agnès Moreau‐Aubry, David Chiron, Catherine Pellat‐Deceunynck
Publikováno v:
HemaSphere, Vol 8, Iss 10, Pp n/a-n/a (2024)
Abstract In multiple myeloma, as in B‐cell malignancies, mono‐ and especially bi‐allelic TP53 gene inactivation is a high‐risk factor for treatment resistance, and there are currently no therapies specifically targeting p53 deficiency. In thi
Externí odkaz:
https://doaj.org/article/13eb39e4b90348b0a8b866dcf7917e42
Autor:
Patricia, Gomez-Bougie, Christelle, Dousset, Geraldine, Descamps, Anne, Schnitzler, Logan, Audiger, Arnaud, Tessier, Didier, Dubreuil, Jacques, Lebreton, Catherine, Pellat-Deceunynck, Martine, Amiot
Publikováno v:
British journal of haematology. 180(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69959f606121b40569753131c6cf5570
https://pubmed.ncbi.nlm.nih.gov/27523575
https://pubmed.ncbi.nlm.nih.gov/27523575
Autor:
Nour Mhaidly, Fabrice Journe, Ahmad Najem, Louis Stock, Anne Trelcat, Didier Dequanter, Sven Saussez, Géraldine Descamps
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12813 (2023)
Tumor-associated macrophages are key components of the tumor microenvironment and play important roles in the progression of head and neck cancer, leading to the development of effective strategies targeting immune cells in tumors. Our study demonstr
Externí odkaz:
https://doaj.org/article/d18795b1c9c34055be114725f2d31b0c
Autor:
Tycho de Bakker, Fabrice Journe, Géraldine Descamps, Sven Saussez, Tatiana Dragan, Ghanem Ghanem, Mohammad Krayem, Dirk Van Gestel
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
TP53 mutation is one of the most frequent genetic alterations in head and neck squamous cell carcinoma (HNSCC) and results in an accumulation of p53 protein in tumor cells. This makes p53 an attractive target to improve HNSCC therapy by restoring the
Externí odkaz:
https://doaj.org/article/3d81f6f1c6f54fd3a35bd3c0e6af4103
Autor:
Sonia Furgiuele, Géraldine Descamps, Lorena Cascarano, Ambre Boucq, Christine Dubois, Fabrice Journe, Sven Saussez
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6385 (2022)
The head and neck tumor microenvironment (TME) is highly infiltrated with macrophages. More specifically, tumor-associated macrophages (TAM/M2-like) are one of the most critical components associated with poor overall survival in head and neck cancer
Externí odkaz:
https://doaj.org/article/952ef5455fba4a3e9bb8bbb30f68e820
Autor:
Sonia Furgiuele, Géraldine Descamps, Jerome R. Lechien, Didier Dequanter, Fabrice Journe, Sven Saussez
Publikováno v:
Cells, Vol 11, Iss 13, p 2050 (2022)
We assessed immune cell infiltrates to develop an immunoscore for prognosis and to investigate its correlation with the clinical data of patients with head and neck cancer. CD8, FoxP3, and CD68 markers were evaluated by immunohistochemistry in 258 ca
Externí odkaz:
https://doaj.org/article/5a1e389f78d947c09332195e614d22b2
Autor:
Benoît Tessoulin, Agnès Moreau-Aubry, Géraldine Descamps, Patricia Gomez-Bougie, Sophie Maïga, Alban Gaignard, David Chiron, Emmanuelle Ménoret, Steven Le Gouill, Philippe Moreau, Martine Amiot, Catherine Pellat-Deceunynck
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-13 (2018)
Abstract Background Human myeloma cell lines (HMCLs) are widely used for their representation of primary myeloma cells because they cover patient diversity, although not fully. Their genetic background is mostly undiscovered, and no comprehensive stu
Externí odkaz:
https://doaj.org/article/5588860c88bf45adab3b11a355d742eb
Autor:
Géraldine Descamps, Laurine Verset, Anne Trelcat, Claire Hopkins, Jérome R. Lechien, Fabrice Journe, Sven Saussez
Publikováno v:
Biology, Vol 9, Iss 8, p 235 (2020)
The coronavirus pandemic raging worldwide since December 2019 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which invades human cells via the angiotensin-converting enzyme 2 (ACE2) receptor. Although it has already be
Externí odkaz:
https://doaj.org/article/4b138660e3784ab8bc0982e49a14bb1f