Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Geraldine A. Walsh"'
Autor:
Julija Rabcuka, Peter A. Smethurst, Katharina Dammert, Jarob Saker, Gemma Aran, Geraldine M. Walsh, Joanne C.G. Tan, Margarita Codinach, Ken McTaggart, Denese C. Marks, Stephan J.L. Bakker, Amy McMahon, Emanuele Di Angelantonio, David J. Roberts, Slawomir Blonski, Piotr M. Korczyk, Atsushi Shirakami, Rebecca Cardigan, Pawel Swietach
Publikováno v:
EBioMedicine, Vol 111, Iss , Pp 105498- (2025)
Summary: Background: Metrics evaluating the functional quality of red blood cells (RBCs) must consider their role in oxygen delivery. Whereas oxygen-carrying capacity is routinely reported using haemoglobin assays, the rate of oxygen exchange is not
Externí odkaz:
https://doaj.org/article/c5a8c189888342bfa265c3ca5dd6614c
Publikováno v:
Vox Sanguinis.
Publikováno v:
Thrombosis Research. 139:50-55
Studies of sex-dependent differences in platelet aggregation and glycoprotein (GP)IIb/IIIa activation have demonstrated that platelets from females are more sensitive to agonists than those from males. To date, there is little understanding of these
Autor:
Ziad Solh, Andrew W. Shih, Peter Schubert, William P. Sheffield, Mia Golder, Geraldine M. Walsh, Margaret Fearon
Publikováno v:
Transfusion Medicine Reviews
Testing donations for pathogens and deferring selected blood donors have reduced the risk of transmission of known pathogens by transfusion to extremely low levels in most developed countries. Protecting the blood supply from emerging infectious thre
Publikováno v:
Transfusion Medicine Reviews. 29:181-194
Plasma obtained via whole blood donation processing or via apheresis technology can either be transfused directly to patients or pooled and fractionated into plasma protein products that are concentrates of 1 or more purified plasma protein. The evid
Autor:
Dana V. Devine, Geraldine M. Walsh
Publikováno v:
ISBT Science Series. 9:56-63
Publication of research findings and novel concepts in the biomedical literature is the mainstay of knowledge mobilization. The communication of scientific work as papers follows a well-established framework. A clear understanding of the nature of th
Autor:
Marie-Therese Cooney, Sarah A. McGarrigle, Ian D. Graham, Niamh Moran, Philip Mayne, Sarah O'Neill, Geraldine M. Walsh, Ahmad Monavari, Patrick Collins
Publikováno v:
Platelets. 22:63-71
Elevated levels of plasma homocysteine (Hcy) are an independent risk factor for cardiovascular disease and thrombosis. The molecular basis for this phenomenon is not known but may relate to modification of cell surface thiols. The platelet specific i
Autor:
Jonathan N. Thon, Edwin D.W. Moore, Cindy Chen, Dana V. Devine, Geraldine M. Walsh, Peter Schubert, Juergen Kast
Publikováno v:
Transfusion. 49:1944-1955
Background The term platelet storage lesion (PSL) describes the structural and biochemical changes in platelets (PLTs) during storage. These are typified by alterations of morphologic features and PLT metabolism leading to reduced functionality and h
Publikováno v:
Molecular & Cellular Proteomics. 8:887-903
Nitroxyl (HNO) exhibits many important pharmacological effects, including inhibition of platelet aggregation, and the HNO donor Angeli's salt has been proposed as a potential therapeutic agent in the treatment of many diseases including heart failure
Publikováno v:
Biochemistry. 43:473-480
The molecular mechanisms involved in regulating the activation-dependent conformational switch in integrins are not known although recent evidence suggests that integrins are a direct target for redox modulation. We have identified an endogenous inte