Výsledky vyhledávání - "Geraldine, Descamps"

Akademický článek

Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells

Autor: Benoit Tessoulin, Geraldine Descamps, Christelle Dousset, Martine Amiot, Catherine Pellat-Deceunynck

Publikováno v: Frontiers in Oncology, Vol 9 (2019)

Prima-1Met (APR-246) was previously shown to be dependent on glutathione inhibition and on ROS induction in cancer cells with mutated or deleted TP53. Because this ROS induction was, at least in part, due to a direct interference with the thioredoxin

Externí odkaz: https://doaj.org/article/3bacdfcf8c9b4a4e916a25e68db322e7

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TP53 CRISPR/Cas9 Reveals Strict BAX Dependence in the Response to BH3 Mimetic Targeting MCL1

Autor: Romane Durand, Domitille Costes-Tertrais, Geraldine Descamps, Christelle Dousset, Sophie Maïga, Jean-Baptiste Alberge, Elise Douillard, Jennifer Derrien, Celine Bellanger, David Chiron, Stephane Minvielle, Cyrille Touzeau, Philippe Moreau, Martine Amiot, Patricia Gomez-Bougie, Agnes Moreau-Aubry, Catherine Pellat-Deceunynck

Publikováno v: Blood. 140:4198-4199

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68358fc5d38745cca0becedcd4afc4fe
https://doi.org/10.1182/blood-2022-155862

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The selectivity of Marinopyrrole A to induce apoptosis in MCL1

Autor: Patricia, Gomez-Bougie, Christelle, Dousset, Geraldine, Descamps, Anne, Schnitzler, Logan, Audiger, Arnaud, Tessier, Didier, Dubreuil, Jacques, Lebreton, Catherine, Pellat-Deceunynck, Martine, Amiot

Publikováno v: British journal of haematology. 180(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::69959f606121b40569753131c6cf5570
https://pubmed.ncbi.nlm.nih.gov/27523575

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Periodical

Reports Summarize Myeloma Study Results from University of Nantes (A P53 Score Derived From Tp53 Crispr/cas9 Hmcls Predicts Survival and Reveals a Major Role of Bax In the Response To Bh3 Mimetics).

Publikováno v: Hematology Week; 6/18/2024, p1307-1307, 1p

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Akademický článek

RITA (Reactivating p53 and Inducing Tumor abnormal Apoptosis) is efficient against TP53^abnormal myeloma cells independently of the p53 pathway.

Autor: Surget, Sylvanie^1,2,3 sylvanie.surget@orange.fr, Descamps, Géraldine^1,2,3 geraldine.descamps@univ-nantes.fr, Brosseau, Carole^1,2,3 carole.brosseau@inserm.fr, Normant, Vincent^1,2,3 vnormant@laposte.net, Maïga, Sophie^1,2,3 sophie.maiga@inserm.fr, Gomez-Bougie, Patricia^1,2,3 Patricia.Gomez@univ-nantes.fr, Gouy-Colin, Nadège⁴ nadege.gouy@chu-nantes.fr, Godon, Catherine⁴ catherine.godon@chu-nantes.fr, Béné, Marie C.² mariecbene@gmail.com, Moreau, Philippe^2,5 philippe.moreau@chu-nantes.fr, Le Gouill, Steven^1,2,3,5 steven.legouill@chu-nantes.fr, Amiot, Martine^1,2,3,5,6 martine.amiot@inserm.fr, Pellat-Deceunynck, Catherine^1,2,3,5 catherine.pellat-deceunynck@inserm.fr

Publikováno v: BMC Cancer. 2014, Vol. 14 Issue 1, p1-22. 22p.

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