Výsledky vyhledávání - "Gerald Wayne Gough"

Complement Factor H Is Critical in the Maintenance of Retinal Perfusion

Autor: Jaimie Hoh Kam, Peter Lundh von Leithner, Peter J. Coffey, Glen Jeffery, James W B Bainbridge, Gerald Wayne Gough, Ian Richard Catchpole

Publikováno v: The American Journal of Pathology. 175:412-421

Vascular pathologies are known to be associated with age-related macular degeneration. Recently, age-related macular degeneration was associated with a single-nucleotide substitution of the complement factor H (CFH) gene, part of the alternative path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581699a9e41909cfb67bf3174228bbe7
https://doi.org/10.2353/ajpath.2009.080927

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Cell-mediated immune responses to COPV early proteins

Autor: Margaret Stanley, Davina M. Anderson, Richard A. Moore, Gerald Wayne Gough, Suchitra Jain

Publikováno v: Virology. 356:23-34

Cell-mediated immunity plays a key role in the regression of papillomavirus-induced warts and intra-epithelial lesions but the target antigens that induce this response are not clear. Canine oral papillomavirus (COPV) infection of the oral cavity in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3257a24d83413f71aee6f857d5d7ffbe
https://doi.org/10.1016/j.virol.2006.07.032

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Human Papillomavirus Genotype Distribution in Low-Grade Cervical Lesions: Comparison by Geographic Region and with Cervical Cancer

Autor: Jeanne M. Pimenta, Rashida K. Rana, Gary M. Clifford, Silvia Franceschi, Jennifer S. Smith, Gerald Wayne Gough

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 14:1157-1164

Low-grade squamous intraepithelial lesions (LSIL) associated with certain human papillomavirus (HPV) genotypes may preferentially progress to cervical cancer. HPV genotyping may thus have the potential to improve the effectiveness of screening progra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06500f55aa91fb829350146273a4adc
https://doi.org/10.1158/1055-9965.epi-04-0812

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Intraepithelial DNA Immunisation with a Plasmid Encoding a Codon Optimised COPV E1 Gene Sequence, But Not the Wild-Type Gene Sequence Completely Protects against Mucosal Challenge with Infectious COPV in Beagles

Autor: Kate L White, Sarah Marina Walcott, Michael A. Romanos, Andrew R. Lloyd, Elmer B. Santos, Gerald Wayne Gough, Philip K. Nicholls, Vanita Parmar, Lindy L. Thomsen, Davina M. Anderson, Richard A. Moore, Margaret Stanley, Peter Topley

Publikováno v: Virology. 304(2):451-459

DNA plasmids encoding the open reading frames of canine oral papillomavirus (COPV) nonstructural early genes E1, E2, or E7 protein were delivered into both oral mucosal and cutaneous epithelial sites in beagle dogs using particle-mediated immunothera

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Distinct responses of the herpes simplex virus and varicella zoster virus immediate early promoters to the cellular transcription factors Brn-3a and Brn-3b

Autor: Robert S. Coffin, David S. Latchman, Gerald Wayne Gough, Janet Brownlees, Jeffrey I. Cohen, Paul Watts, Suzanne Thomas

Publikováno v: The International Journal of Biochemistry & Cell Biology. 31:451-461

The related viruses herpes simplex virus (HSV) and varicella zoster virus (VZV) show distinct but related patterns of latent infection and reactivation in human sensory ganglia. The cellular POU family transcription factors Brn-3a and Brn-3b are expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5757cbcb9d6645abd9d1cf202a295c8f
https://doi.org/10.1016/s1357-2725(98)00151-4

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Cell type specific repression of the varicella zoster virus immediate early gene 62 promoter by the cellular Oct-2 transcription factor

Autor: David S. Latchman, Suzanne Thomas, Jeffrey I. Cohen, Gerald Wayne Gough, Robert S. Coffin, Yamini Patel

Publikováno v: Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1397:268-274

The cellular transcription factor Oct-2.1 has previously been shown to repress the transactivation of the varicella zoster virus (VZV) immediate early gene promoter by viral transactivators but not to inhibit its basal activity. In the case of the re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6431738f2d840cd403cda534ec788eb
https://doi.org/10.1016/s0167-4781(97)00216-9

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Absence of canine oral papillomavirus DNA following prophylactic L1 particle-mediated immunotherapeutic delivery vaccination

Autor: Elmer B. Santos, Philip K. Nicholls, Gerald Wayne Gough, Richard A. Moore, Margaret Stanley

Publikováno v: Journal of General Virology. 83:2299-2301

In the canine oral papillomavirus (COPV) model, following wart regression, COPV DNA was detected by PCR at the challenge site. However, following particle-mediated immunotherapeutic delivery (PMID) of COPV L1 and subsequent challenge, no COPV DNA cou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d492adf188b7e736abe3a130b51b239
https://doi.org/10.1099/0022-1317-83-9-2299

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