Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Gerald W. Both"'
Autor:
Tomáš Hanke, Anne Bridgeman, Yaowaluck Roshorm, Jan Shaw, Richard Hopkins, Gerald W. Both, Linda J. Lockett, Zheng-Zhou Xu
Ovine adenovirus type 7 (OAdV) is the prototype member of the genus Atadenovirus. No immunity to the virus has so far been detected in human sera. We describe the construction and evaluation of a candidate HIV-1 vaccine based on OAdV and its utilisat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9942f0c03bf57316af5cf8cda9c8aa1e
https://ora.ox.ac.uk/objects/uuid:eca5130c-e1b6-48df-8a5b-39c6e33f6835
https://ora.ox.ac.uk/objects/uuid:eca5130c-e1b6-48df-8a5b-39c6e33f6835
Autor:
Alice Mbewe-Mvula, Gerald W. Both, Anne Bridgeman, Tomáš Hanke, Jerald C. Sadoff, Richard Hopkins, Joan Joseph, John Fulkerson, Charles Bourne
Publikováno v:
European Journal of Immunology. 41:3542-3552
The desire to induce HIV-1-specific responses soon after birth to prevent breast milk transmission of HIV-1 led us to propose a vaccine regimen which primes HIV-1-specific T cells using a recombinant Mycobacterium bovis bacillus Calmette-Guérin (rBC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9a9513eec29e7053f3381ac4e8e85f
https://doi.org/10.1002/eji.201141962
https://doi.org/10.1002/eji.201141962
Autor:
Joan Joseph, Gerald W. Both, Tomáš Hanke, Emma Gostick, Nicola Borthwick, Hui Yee Greenaway, Daniel C. Douek, Máire F. Quigley, Vanessa Venturi, Richard Hopkins, John Fulkerson, Maximillian Rosario, David Price, Jerald C. Sadoff
Publikováno v:
Journal of Virology. 84:5898-5908
Mycobacterium bovisbacillus Calmette-Guérin (BCG), which elicits a degree of protective immunity against tuberculosis, is the most widely used vaccine in the world. Due to its persistence and immunogenicity, BCG has been proposed as a vector for va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f87b76f383aed018a47d78453c65d47
https://doi.org/10.1128/jvi.02607-09
https://doi.org/10.1128/jvi.02607-09
Publikováno v:
Journal of Virology. 82:7346-7356
A three-dimensional (3D) cryoelectron microscopy reconstruction of the prototype Atadenovirus (OAdV [an ovine adenovirus isolate]) showing information at a 10.6-Å resolution (0.5 Fourier shell correlation) was derived by single-particle analysis. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b77ebd579f4f8c52c1acf81e0eec01
https://doi.org/10.1128/jvi.00764-08
https://doi.org/10.1128/jvi.00764-08
Autor:
Yosuke Kawakami, David T. Curiel, Seiji Yamamoto, Gerald W. Both, Yuko Tsuruta, Kenzaburo Tani, Masaharu Nakayama, Joel N. Glasgow, Boglarka Banizs, Joanne T. Douglas
Publikováno v:
Virology. 350(1):103-115
Many clinically important tissues are refractory to adenovirus (Ad) infection due to negligible levels of the primary Ad5 receptor the coxsackie and adenovirus receptor CAR. Thus, development of novel CAR-independent Ad vectors should lead to therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f223c50ce38bdaa6d889e5829de206d
Publikováno v:
Virology. 342:159-166
Ovine adenovirus serotype 7 (OAdV), the prototype atadenovirus, has gene homologues for most mastadenovirus structural proteins but lacks proteins V and IX. Instead, OAdV has structural proteins of 32 and 42 kDa although the gene encoding the latter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e637151244f2f96ca0c01a95d2e4cae
https://doi.org/10.1016/j.virol.2005.07.020
https://doi.org/10.1016/j.virol.2005.07.020
Publikováno v:
Vaccine. 22:2717-2721
Ovine atadenovirus (OAdV) is a novel gene transfer vector with excellent in vivo gene transfer characteristics. In the present study, we have investigated the ability of an OAdV vector to mediate a T cell response to an antigen of the hepatitis C vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7be6834b0075a6ec4c905241dbf1e4
https://doi.org/10.1016/j.vaccine.2004.01.048
https://doi.org/10.1016/j.vaccine.2004.01.048
Autor:
Gerald W. Both
Publikováno v:
Immunology & Cell Biology. 82:189-195
The ovine adenovirus isolate OAdV287 is the prototype of the newly recognized genus of atadenoviruses. Although not as well studied as human mastadenoviruses, a substantial amount of work has now been carried out with this virus and an understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38952b9e2abc61ce46e53ece651307ea
https://doi.org/10.1046/j.0818-9641.2004.01223.x
https://doi.org/10.1046/j.0818-9641.2004.01223.x
Autor:
Gerald W. Both, Pamela J. Russell, Rosetta Martiniello-Wilks, Allison P Dane, Elin Mortensen, Dale J. Voeks, Xiao Yang Wang, J Shaw, Geetha Jeyakumar
Publikováno v:
The Journal of Gene Medicine. 6:43-54
Background Gene-directed enzyme prodrug therapy (GDEPT) based on the E. coli enzyme purine nucleoside phosphorylase (PNP) represents a new approach for treating slow growing tumours like prostate cancer (PCa). Expressed enzyme converts a systemically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f75e1f05c4e8d7b7d83d9d29e05ce8
https://doi.org/10.1002/jgm.474
https://doi.org/10.1002/jgm.474
Autor:
Lee Carpenter, Trevor J. Biden, Zheng Z. Xu, Gerald W. Both, Philip Poronnik, Chris J. Mitchell
Publikováno v:
Diabetes. 53:53-60
The role of protein kinase C (PKC) in glucose-stimulated insulin secretion (GSIS) is controversial. Using recombinant adenoviruses for overexpression of PKC alpha and PKC delta, in both wild-type (WT) and kinase-dead (KD) forms, we here demonstrate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f269f1ae4b335400b29eb202c70ebd0d
https://doi.org/10.2337/diabetes.53.1.53
https://doi.org/10.2337/diabetes.53.1.53