Výsledky vyhledávání - "Gerald V. Fontenay"

Akademický článek

Identification of fluorescent compounds with non-specific binding property via high throughput live cell microscopy.

Autor: Sangeeta Nath, Virginia A Spencer, Ju Han, Hang Chang, Kai Zhang, Gerald V Fontenay, Charles Anderson, Joel M Hyman, Marit Nilsen-Hamilton, Young-Tae Chang, Bahram Parvin

Publikováno v: PLoS ONE, Vol 7, Iss 1, p e28802 (2012)

INTRODUCTION: Compounds exhibiting low non-specific intracellular binding or non-stickiness are concomitant with rapid clearing and in high demand for live-cell imaging assays because they allow for intracellular receptor localization with a high sig

Externí odkaz: https://doaj.org/article/04ec808a73d948ac861e38b9dff20e29

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Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry

Autor: Weixing Zhao, Lucy Lu, Joseph San Filippo, Gerald V. Fontenay, Patrick Sung, David G. Maranon, Youngho Kwon, Walter J. Chazin, Ryan B. Jensen, Claudia Wiese, Sivaraja Vaithiyalingam, Judit Jimenez-Sainz, Stanley G. Leung

Publikováno v: Molecular Cell. 59:176-187

The tumor suppressor BRCA2 is thought to facilitate the handoff of ssDNA from replication protein A (RPA) to the RAD51 recombinase during DNA break and replication fork repair by homologous recombination. However, we find that RPA-RAD51 exchange requ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccef997587e1bdab83dc42d1c8f82081
https://doi.org/10.1016/j.molcel.2015.05.032

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The Berkeley Center for Structural Biology at the Advanced Light Source

Autor: Kevin Royal, Gerald V. Fontenay, Simon A. Morton, Anthony Rozales, Azer Dauz, Randall Cayford, Petrus H. Zwart, Jeff Dickert, Nathan Smith, Diane Bryant, J. Taylor, Corie Y. Ralston, Stacey Ortega, Marc Allaire, Nicholas K. Sauter, Banumathi Sankaran, Paul D. Adams

Publikováno v: Synchrotron Radiation News. 28:22-27

The Berkeley Center for Structural Biology (BCSB) operates and develops a suite of protein crystallography beamlines at the Advanced Light Source (ALS) located at Lawrence Berkeley National Laboratory (LBNL). Although the ALS was conceived as a low-e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba3e2a27b5d07bc1ab9a09a3d222deaa
https://doi.org/10.1080/08940886.2015.1013417

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Stress Signaling from Human Mammary Epithelial Cells Contributes to Phenotypes of Mammographic Density

Autor: Rosa Anna DeFilippis, Gerald V. Fontenay, Jianxin Zhao, Bahram Parvin, Thea D. Tlsty, Karla Kerlikowske, Kelley T. Patten, Hang Chang, Colleen A. Fordyce

Publikováno v: Cancer Research. 74:5032-5044

Telomere malfunction and other types of DNA damage induce an activin A–dependent stress response in mortal nontumorigenic human mammary epithelial cells that subsequently induces desmoplastic-like phenotypes in neighboring fibroblasts. Some charact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075d8ac7df197794874856ff8198d5bb
https://doi.org/10.1158/0008-5472.can-13-3390

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Stiffness of the microenvironment upregulates ERBB2 expression in 3D cultures of MCF10A within the range of mammographic density

Autor: Ju Han, Hang Chang, Gerald V. Fontenay, Qingsu Cheng, Matthew Henderson, Cemal Cagatay Bilgin, Bahram Parvin

Publikováno v: Scientific Reports

The effects of the stiffness of the microenvironment on the molecular response of 3D colony organization, at the maximum level of mammographic density (MD), are investigated. Phenotypic profiling reveals that 3D colony formation is heterogeneous and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aef957e4cb53ee6e9979a018b3e1f28
https://doi.org/10.1038/srep28987

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Phenotypic characterization of breast invasive carcinoma via transferable tissue morphometric patterns learned from glioblastoma multiforme

Autor: Hang Chang, Yunfu Wang, Ju Han, Gerald V. Fontenay, Jian-Hua Mao

Publikováno v: Han, J; Fontenay, GV; Wang, Y; Mao, JH; & Chang, H. (2016). Phenotypic characterization of breast invasive carcinoma via transferable tissue morphometric patterns learned from glioblastoma multiforme. Proceedings-International Symposium on Biomedical Imaging, 2016-June, 1025-1028. doi: 10.1109/ISBI.2016.7493440. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/51t5t0ws
ISBI

© 2016 IEEE. Quantitative analysis of whole slide images (WSIs) in a large cohort may provide predictive models of clinical outcome. However, the performance of the existing techniques is hindered as a result of large technical variations (e.g., fix

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2580b50dd4a76cd0f68bc77b3b5890e4
http://www.escholarship.org/uc/item/51t5t0ws

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Multiscale iterative voting for differential analysis of stress response for 2D and 3D cell culture models

Autor: Qing Yang, Hang Chang, M. Helen Barcellos‐Hoff, Ju Han, Gerald V. Fontenay, Torsten Groesser, Bahram Parvin

Publikováno v: Journal of Microscopy. 241:315-326

Summary Three-dimensional (2D) cell culture models have emerged as the basis for improved cell systems biology. However, there is a gap in robust computational techniques for segmentation of these model systems that are imaged through confocal or dec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbf8c2cc8da877a6c8955994974490ee
https://doi.org/10.1111/j.1365-2818.2010.03442.x

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