Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Gerald Stubbs"'
Autor:
Amy Kendall, C. David Sherrill, Nicholas V. Hud, Carlos H. Borca, Asem Alenaizan, Suneesh C. Karunakaran, Gerald Stubbs, Gary B. Schuster
Publikováno v:
Journal of the American Chemical Society. 143:6079-6094
Aqueous solutions of equimolar mixtures of 2,4,6-triaminopyrimidine (TAP) and carboxylic acid substituted cyanuric acid (CyCo6 or R-4MeCyCo6) monomers self-assemble into gel-forming supramolecular polymers. Macroscopic fibers drawn from these mixture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3ab00f6ca151d8a5e6fd1e0545265c
https://doi.org/10.1021/jacs.0c12010
https://doi.org/10.1021/jacs.0c12010
Autor:
Surabhi Mishra, Momin Haider, Ana L. Barrán-Berdón, L. Jeannine Brady, Stephen J. Hagen, Amy Kendall, Joanna R. Long, Elena G. Yarmola, Gerald Stubbs, Joyce C. Morales-Aparicio, Gregory Ottenberg, Sebastian Ocampo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Streptococcus mutans is an etiologic agent of human dental caries that forms dental plaque biofilms containing functional amyloids. Three amyloidogenic proteins, P1, WapA, and Smu_63c were previously identified. C123 and AgA are naturally occurring a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77527e8bb915c1cc238ffb17c3a4a12
http://link.springer.com/article/10.1038/s41598-020-62115-7
http://link.springer.com/article/10.1038/s41598-020-62115-7
Autor:
Gerald Stubbs, Joseph P. R. O. Orgel
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:a229-a229
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::648a9b939e755a14b551110e389c41be
https://doi.org/10.1107/s0108767321097701
https://doi.org/10.1107/s0108767321097701
Autor:
William F. DeGrado, Stanley B. Prusiner, Julia Becker, Mark J. S. Kelly, Manasi P. Bhate, Srabasti Acharya, Mimi Nick, Gerald Stubbs, Kathleen Robinson, Haifan Wu, Carlo Condello, Feng Gai, Jan Stöhr, Jeffrey M. Rodgers, Yibing Wu, Thomas Lemmin, Noah R. Johnson
Publikováno v:
Nature Chemistry. 9:874-881
The self-propagation of misfolded conformations of tau underlies neurodegenerative diseases, including Alzheimer’s disease. There is considerable interest in discovering the minimal sequence and active conformational nucleus that defines this self-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40adadc35328763a61601ae52bb7ac8f
https://doi.org/10.1038/nchem.2754
https://doi.org/10.1038/nchem.2754
Autor:
Rina K. Dukor, Gerald Stubbs, Dmitry Kurouski, Laurence A. Nafie, Igor K. Lednev, Maruda Shanmugasundaram, William Wan
Publikováno v:
J Phys Chem B
Amyloid fibril polymorphism is not well understood despite its potential importance for biological activity and associated toxicity. Controlling the polymorphism of mature fibrils including their morphology and supramolecular chirality by postfibrill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb8b61a443bac4b129ce4816cb8ca55
https://doi.org/10.1021/acs.jpcb.5b04779
https://doi.org/10.1021/acs.jpcb.5b04779
Autor:
Gerald Stubbs, Amy Kendall
Publikováno v:
Crystallography Reviews. 22:84-101
In many plant and bacterial viruses, a filamentous nucleocapsid makes up the entire virus particle. These viruses usually form fibres naturally, but they do not crystallize. Fibre diffraction has therefore been the method of choice for structural stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cfd445455252d2e3a2f7f81cc762503
https://doi.org/10.1080/0889311x.2015.1025771
https://doi.org/10.1080/0889311x.2015.1025771
Autor:
Gerald Stubbs, William Wan
Publikováno v:
Proceedings of the National Academy of Sciences. 111:5201-5206
The highly ordered and reproducible structure of the fungal prion HET-s makes it an excellent model system for studying the inherent properties of prions, self-propagating infectious proteins that have been implicated in a number of fatal diseases. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04432db6ca9d5d2ca581ae1e5af8b879
https://doi.org/10.1073/pnas.1322933111
https://doi.org/10.1073/pnas.1322933111
Autor:
Gerald Stubbs, William Wan
Publikováno v:
Prion. 8:178-182
One fundamental property of prions is the formation of strains-prions that have distinct biological effects, despite a common amino acid sequence. The strain phenomenon is thought to be caused by the formation of different molecular structures, each
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804a7e606ad26298f009478f6b43e2ce
https://doi.org/10.4161/pri.28126
https://doi.org/10.4161/pri.28126
Autor:
Gerald Stubbs, Jan Stöhr
Publikováno v:
Cold Spring Harbor perspectives in medicine. 7(6)
Prion diseases are characterized by the deposition of amyloids, misfolded conformers of the prion protein. The misfolded conformation is self-replicating, by a mechanism solely enciphered in the conformation of the protein. Because of low solubility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0354238517939be2f65d099eabfc469b
https://pubmed.ncbi.nlm.nih.gov/28003279
https://pubmed.ncbi.nlm.nih.gov/28003279
Autor:
Gerald Stubbs, Melanie Kalischuk, Matthias Senft, Amy Kendall, Lawrence M. Kawchuk, Franziska Diekstall, Ulla Neumann, Gundula A. Noll, Dirk Prüfer, Boje Müller, Richard M. Twyman, Boris A Kommor, Andreas Heilmann, Sira Groscurth, Matthias Menzel, Vladislav Krzyzanek, Stefan Schwan
Publikováno v:
Biomacromolecules. 13:3076-3086
Forisomes are protein polymers found in leguminous plants that have the remarkable ability to undergo reversible "muscle-like" contractions in the presence of divalent cations and in extreme pH environments. To gain insight into the molecular basis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efd4fb224b108626a4fb03ae2d134bb
https://doi.org/10.1021/bm3008499
https://doi.org/10.1021/bm3008499