Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gerald Stephen Brooke"'
Autor:
S G Reams, L J Slieker, Harlan Beall Long, R M Belagaje, W F Heath, Walter N. Shaw, Gerald Stephen Brooke, Ronald E. Chance, C Roundtree, Jules A. Hoffmann
Publikováno v:
Journal of Biological Chemistry. 267:419-425
The hormone insulin is synthesized in the beta cell of the pancreas as the precursor, proinsulin, where the carboxyl terminus of the B-chain is connected to the amino terminus of the A-chain by a connecting or C-peptide. Proinsulin is a weak insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9b98988c87152932241e272ee40aa14
https://doi.org/10.1016/s0021-9258(18)48511-0
https://doi.org/10.1016/s0021-9258(18)48511-0
Publikováno v:
Biochemical and Biophysical Research Communications. 177:932-938
Amylin, an islet amyloid peptide secreted by the pancreatic beta cell, has been proposed as a humoral regulator of islet insulin secretion. Four separate preparations of amylin were tested for effects on hormone secretion in both freshly isolated and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc7b3f3578d82040ab360f027617ebc
https://doi.org/10.1016/0006-291x(91)90628-k
https://doi.org/10.1016/0006-291x(91)90628-k
Autor:
K L Sundell, Jules A. Hoffmann, L J Slieker, Gerald Stephen Brooke, L Fan, Harlan Beall Long, L K Green, Ronald E. Chance, Richard D. DiMarchi, David B. Flora, James E. Shields, P. L. Surface
Publikováno v:
Diabetologia. 40
Inversion of the natural sequence of the B chain of human insulin (HI) from ProB28LysB29 to LysB28ProB29 generates an insulin analogue with reduced tendency to self-associate. Since this substitution increases the homology of insulin to insulin-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2a826ed7c01046aa5b2a68eecce6a5
https://pubmed.ncbi.nlm.nih.gov/9248702
https://pubmed.ncbi.nlm.nih.gov/9248702
Autor:
Victor Cracknell, Noel Mowat, Gerald Stephen Brooke, Timothy Doel, Charles Gale, Richard D. DiMarchi
Publikováno v:
Science. 232:639-641
A chemically synthesized peptide consisting essentially of two separate regions (residues 141 to 158 and 200 to 213) of a virus coat protein (VP1) from the O1 Kaufbeuren strain of foot-and-mouth disease virus was prepared free of any carrier protein.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c69b39bf9a162d9cda5f80ea97bc481
https://doi.org/10.1126/science.3008333
https://doi.org/10.1126/science.3008333
Publikováno v:
Peptides ISBN: 9789401095976
Peptides
Peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76a7ec971352165315ba698bcd3d1aa7
https://doi.org/10.1007/978-94-010-9595-2_158
https://doi.org/10.1007/978-94-010-9595-2_158
Publikováno v:
The Journal of general virology. 69
Summary Foot-and-mouth disease virus challenge experiments in guinea-pigs and immunoassays with a range of peptides equivalent to either or both of the sequences 141 to 158 and 200 to 213 of VP1 showed the most effective structure, in terms of protec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c54d412c7e97efea68a69f3ea7cba2a
https://pubmed.ncbi.nlm.nih.gov/2457649
https://pubmed.ncbi.nlm.nih.gov/2457649