Výsledky vyhledávání - "Gerald Staedtler"

Dual Vasopressin Receptor Antagonism to Improve Congestion in Patients With Acute Heart Failure: Design of the AVANTI Trial

Autor: Finn Gustafsson, Adriaan A. Voors, Gerald Staedtler, Pablo Colorado, Daniel Burkhoff, Faiez Zannad, Wilfried Dinh, James E. Udelson, Steven R. Goldsmith, Peter Kolkhof

Publikováno v: JOURNAL OF CARDIAC FAILURE, 27(2), 233-241. Churchill Livingstone
Goldsmith, S R, Burkhoff, D, Gustafsson, F, Voors, A, Zannad, F, Kolkhof, P, Staedtler, G, Colorado, P, Dinh, W & Udelson, J E 2021, ' Dual Vasopressin Receptor Antagonism to Improve Congestion in Patients With Acute Heart Failure : Design of the AVANTI Trial ', Journal of Cardiac Failure, vol. 27, no. 2, pp. 233-241 . https://doi.org/10.1016/j.cardfail.2020.10.007

BACKGROUND: Loop diuretics are the main treatment for patients with acute heart failure, but are associated with neurohormonal stimulation and worsening renal function and do not improve long-term outcomes. Antagonists to arginine vasopressin may pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e630485bca8ecff58ef92710b4d37d8b
https://doi.org/10.1016/j.cardfail.2020.10.007

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Long-Term Efficacy and Safety of Molidustat for Anemia in Chronic Kidney Disease: DIALOGUE Extension Studies

Autor: Gerald Staedtler, Kazuma Iekushi, Thilo Krueger, Iain C. Macdougall, Tadao Akizawa, Megumi Taguchi, Jeffrey S. Berns, Thomas Bernhardt

Publikováno v: Am J Nephrol

Background: Molidustat, a novel hypoxia-inducible factor-prolyl hydroxylase inhibitor, is being investigated for the treatment of anemia associated with chronic kidney disease (CKD). The efficacy and safety of molidustat were recently evaluated in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac0644e7a326e6f75c4d5b71df658cb
https://doi.org/10.1159/000499111

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Comparison of Occlusive and Open Application in a Psoriasis Plaque Test Design, Exemplarily Using Investigations of Mapracorat 0.1% Ointment versus Vehicle and Reference Drugs

Autor: Ragna Williams, W. Wigger-Alberti, Gerald Staedtler, Yi-Ling von Mackensen, Maciej Hoffman-Wecker, Kaweh Shakery, Richard Nkulikiyinka, Ulrike Grossmann

Publikováno v: Skin Pharmacology and Physiology. 30:102-114

Background/Aims: Psoriasis plaque tests (PPTs) are important tools in the early phases of antipsoriatic drug development. Two distinct PPT design variants (open vs. occluded drug application) are commonly used, but no previous work has aimed to direc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a9c8342f53017bb27c424f3d8ea33b
https://doi.org/10.1159/000458415

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Patient-reported outcomes of azelaic acid foam 15% for patients with papulopustular rosacea: secondary efficacy results from a randomized, controlled, double-blind, phase 3 trial

Autor: Stephen, Tyring, James A, Solomon, Gerald, Staedtler, Jason P, Lott, Richard, Nkulikiyinka, Kaweh, Shakery

Publikováno v: Cutis. 98(4)

Patient-reported treatment outcomes are important for evaluating the impact of drug therapies on patient experience. A randomized, double-blind, vehicle-controlled, parallel-group, multicenter, phase 3 study was conducted in 961 participants to asses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f92249ccc7a89e16eba4b0668247c40
https://pubmed.ncbi.nlm.nih.gov/27874885

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Investigator-reported efficacy of azelaic acid foam 15% in patients with papulopustular rosacea: secondary efficacy outcomes from a randomized, controlled, double-blind, phase 3 trial

Autor: James A, Solomon, Stephen, Tyring, Gerald, Staedtler, Meike, Sand, Richard, Nkulikiyinka, Kaweh, Shakery

Publikováno v: Cutis. 98(3)

Papulopustular rosacea (PPR) is characterized by centrofacial papules and pustules commonly associated with erythema. To compare investigator-reported efficacy outcomes for azelaic acid (AzA) foam 15% versus vehicle foam in PPR, a randomized, vehicle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a7cd4a1f641fdf7609b095119ca0b715
https://pubmed.ncbi.nlm.nih.gov/27814413

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A phase 3 randomized, double-blind, vehicle-controlled trial of azelaic acid foam 15% in the treatment of papulopustular rosacea

Autor: Zoe Diana, Draelos, Boni E, Elewski, Julie C, Harper, Meike, Sand, Gerald, Staedtler, Richard, Nkulikiyinka, Kaweh, Shakery

Publikováno v: Cutis. 96(1)

Rosacea is a chronic relapsing skin disorder primarily affecting the face. Although its etiology is not well defined, rosacea is associated with immune dysregulation and inflammation potentiated by external factors. These manifestations lead to skin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fbe26f87d48ebe1e341557919cc78f14
https://pubmed.ncbi.nlm.nih.gov/26244354

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Azelaic acid foam 15% in the treatment of papulopustular rosacea: a randomized, double-blind, vehicle-controlled study

Autor: Zoe Diana, Draelos, Boni, Elewski, Gerald, Staedtler, Blanka, Havlickova

Publikováno v: Cutis. 92(6)

Rosacea is a common chronic inflammatory skin disease that primarily affects facial skin. Its etiology is unknown, and currently there is no cure. Rosacea can be associated with severe symptoms, including transient erythema (flushing), nontransient e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76e90bfa02283653c083b2759bacffd0
https://pubmed.ncbi.nlm.nih.gov/24416747

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Efficacy of topical azelaic acid (AzA) gel 15% plus oral doxycycline 40 mg versus metronidazole gel 1% plus oral doxycycline 40 mg in mild-to-moderate papulopustular rosacea

Autor: James Q, Del Rosso, Suzanne, Bruce, Michael, Jarratt, Alan, Menter, Gerald, Staedtler

Publikováno v: Journal of drugs in dermatology : JDD. 9(6)

Rosacea is a leading reason why people seek the care of a dermatologist, accounting for nearly 7 million office visits annually. Pharmacologic treatments include both topical and oral medications, which are increasingly being used in combination, esp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::703996c142467d5384dc7701502075c8
https://pubmed.ncbi.nlm.nih.gov/20645521

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