Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gerald Skala"'
Publikováno v:
International Journal of Peptide and Protein Research. 21:127-134
The protected peptide, Ac-Glu(OBut)-D-Phe-D-Trp-Ser(But)-Tyr(But)-D-Lys (Z)-Leu-Arg(Tos)-Pro-Gly-NH2 was synthesized in a stepwise manner on a resin of poly-N-acrylylpyrrolidine using both acid cleavable N alpha-tert.-butyloxycarbonyl and base cleava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc51410c96951f6e744e1a1b881a072
https://doi.org/10.1111/j.1399-3011.1983.tb03086.x
https://doi.org/10.1111/j.1399-3011.1983.tb03086.x
BIDIRECTIONAL SYNTHESIS OF [5-ASPARTIC ACID] ARGININE VASOPRESSIN ON POLY-N-ACRYLYLPYRROLIDINE RESIN
Publikováno v:
International Journal of Peptide and Protein Research. 16:365-371
In the proposed biologically active conformation of vasopressin at its antidiuretic receptor, the side-chain carboxamide moiety of the 5-position asparaginyl residue has been suggested to be an active element for the initiation of the antidiuretic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb28ae52fff8e7d03e0a8a80467bd408
https://doi.org/10.1111/j.1399-3011.1980.tb02960.x
https://doi.org/10.1111/j.1399-3011.1980.tb02960.x
Publikováno v:
Journal of Medicinal Chemistry. 20:1457-1460
Replacement of the aliphatic isoleucine residue in position 3 of oxytocin (the first corner position of the beta-turn in the 20-membered ring of the solution conformation of the hormone) by phenylalanine has been shown to result in analogues with red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a10d60d7c1c5753d5672c14d513a99
https://doi.org/10.1021/jm00221a018
https://doi.org/10.1021/jm00221a018
Publikováno v:
Journal of medicinal chemistry. 21(1)
The synthesis and some biological activities of [4-beta-(2-thienyl)-L-alanine]oxytocin are reported. This analogue has been studied in an ongoing exploration of the biological effects of introducing amino acid residues with bulky hydrophobic side cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64daebeef9105fe25e4a2dc83fcf21c
https://pubmed.ncbi.nlm.nih.gov/619140
https://pubmed.ncbi.nlm.nih.gov/619140
Publikováno v:
Journal of the American Chemical Society. 100(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d6c0c77091e111f27ea533c1cd8d4a
https://pubmed.ncbi.nlm.nih.gov/621350
https://pubmed.ncbi.nlm.nih.gov/621350
Publikováno v:
The Journal of experimental zoology. 209(3)
A mutation in the chicken resulting in total amelia is described. Genetic analysis indicates that the limbless condition is due to an autosomal recessive gene. In the limbless embryos the apical ectodermal ridge is lacking. However both the pectoral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643e4a537574604ff6f8534ec01a942a
https://pubmed.ncbi.nlm.nih.gov/490136
https://pubmed.ncbi.nlm.nih.gov/490136
Autor:
Clark W. Smith, Gerald Skala, Garry L. Degraaf, Warren M. Kati, Donald T. Pals, Judy A. Lawson
Publikováno v:
Clinical and experimental hypertension. Part A, Theory and practice. 7(1)
Orthostatic cardiovascular reflexes were evaluated in conscious cynomolgus monkeys during interruption of the renin-angiotensin system with the renin inhibitor: RIP (Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr-Lys-OH). RIP was synthesized via solid phase tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0cba0036483b17d743c75b68b1059c8
https://pubmed.ncbi.nlm.nih.gov/2986882
https://pubmed.ncbi.nlm.nih.gov/2986882
Publikováno v:
Science (New York, N.Y.). 226(4673)
Application of information derived from a three-dimensional model of vasopressin bound to its antidiuretic receptor resulted in the design and synthesis of a bicyclic vasopressin analog, [5,8-cyclo(1-beta-mercaptopropionic acid,2-phenylalanine,5-aspa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24025b6ac5badfcd18024527786047d1
https://pubmed.ncbi.nlm.nih.gov/6541806
https://pubmed.ncbi.nlm.nih.gov/6541806