Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Gerald Simon"'
Publikováno v:
Discover Applied Sciences; Sep2024, Vol. 6 Issue 9, p1-20, 20p
Publikováno v:
European Respiratory Review, Vol 33, Iss 171 (2024)
The nitric oxide (NO)–soluble guanylate cyclase (sGC)–cyclic guanosine monophosphate (cGMP) pathway plays a key role in the pathogenesis of pulmonary hypertension (PH). Targeted treatments include phosphodiesterase type 5 inhibitors (PDE5i) and s
Externí odkaz:
https://doaj.org/article/fcc206931a994f66a90b04a503a8a748
Autor:
J. Gerry Coghlan, Sean Gaine, Richard Channick, Kelly M. Chin, Camille du Roure, J. Simon R. Gibbs, Marius M. Hoeper, Irene M. Lang, Stephen C. Mathai, Vallerie V. McLaughlin, Lada Mitchell, Gérald Simonneau, Olivier Sitbon, Victor F. Tapson, Nazzareno Galiè
Publikováno v:
ERJ Open Research, Vol 9, Iss 1 (2023)
Further understanding of when to initiate therapies in pulmonary arterial hypertension (PAH) is important to improve long-term outcomes. Post hoc analyses of GRIPHON (NCT01106014) and exploratory analyses of TRITON (NCT02558231) suggested benefit of
Externí odkaz:
https://doaj.org/article/cf357fc51af24a7796e8e8637b6468a1
Autor:
Gerald Simon
Publikováno v:
Journal of Magnetic Resonance. 128:194-198
Quartz crystal temperature sensors (QCTS) were tested for the first time as wireless thermometers in NMR MAS rotors utilizing the NMR RF technique itself for exiting and receiving electro-mechanical quartz resonances. This new tool in MAS NMR has a h
Publikováno v:
Angewandte Makromolekulare Chemie. 202:283-293
Two NMR spectroscopic methods were applied to carbon black filled NR vulcanizates to determine the chemical crosslink density. Both methods give corresponding results. Addition of carbon black leads to a decrease of crosslink density with increasing
Publikováno v:
Rubber Chemistry and Technology. 65:63-77
13C-NMR MAS solid-state spectroscopy and 1H-NMR relaxation measurements have been applied for quantitative determination of crosslink density in sulfur-accelerated NR vulcanizates. It is shown that the 13C-NMR method is able to distinguish between mo
Publikováno v:
Lipids. 2(1)
Quantitative elution of acidic and neutral glycolipids of brain and spinach leaves from silicic acid columns with acetone was demonstrated. Cerebrosides and sulfatides of brain and sulfolipid and glycosyl diglycerides of spinach leaves were eluted qu
Autor:
Stefan Guth, Andrea M. D'Armini, Marion Delcroix, Kazuhiko Nakayama, Elie Fadel, Stephen P. Hoole, David P. Jenkins, David G. Kiely, Nick H. Kim, Irene M. Lang, Michael M. Madani, Hiromi Matsubara, Aiko Ogawa, Jaquelina S. Ota-Arakaki, Rozenn Quarck, Roela Sadushi-Kolici, Gérald Simonneau, Christoph B. Wiedenroth, Bedrettin Yildizeli, Eckhard Mayer, Joanna Pepke-Zaba
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Background Pulmonary endarterectomy (PEA), pulmonary arterial hypertension (PAH) therapy and balloon pulmonary angioplasty (BPA) are currently accepted therapies for chronic thromboembolic pulmonary hypertension (CTEPH). This international CTEPH Regi
Externí odkaz:
https://doaj.org/article/18ed9cff6cfb49e7a57d597ad8bdb811
Publikováno v:
The Journal of Organic Chemistry. 65:3207-3208
Assessment of the REPLACE study composite endpoint in riociguat-treated patients in the PATENT study
Autor:
Gérald Simonneau, Hossein-Ardeschir Ghofrani, Paul A. Corris, Stephan Rosenkranz, Ekkehard Grünig, Jim White, Vallerie V. McLaughlin, David Langleben, Christian Meier, Dennis Busse, Frank Kleinjung, Raymond L. Benza
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
The goal of treatment in patients with pulmonary arterial hypertension is to achieve a low risk status, indicating a favorable long-term outcome. The REPLACE study investigated the efficacy of switching to riociguat in patients with pulmonary arteria
Externí odkaz:
https://doaj.org/article/08adb177c61d4bc5bda85b40834655e2