Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gerald P. Hirsch"'
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 45:91-101
An assay is described for the measurement of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase (HGPRT) locus in Chinese hamster ovary (CHO) cells utilizing resistance to 6-thioguanine (TG). Optimal selection conditions are def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06a03e2b5f0bd6596c41b2dfeb7f779
https://doi.org/10.1016/0027-5107(77)90047-1
https://doi.org/10.1016/0027-5107(77)90047-1
Autor:
Gerald P. Hirsch
Publikováno v:
Mechanisms of Ageing and Development. 9:355-367
The theory is presented that the genetic potential for longevity of a given species in a protected environment is determined by the rate of predation in the wild and by the frequency of spontaneous mutations. A common genetically determined lifespan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0f8a4b825d905900ff23e6334c78c6
https://doi.org/10.1016/0047-6374(79)90111-8
https://doi.org/10.1016/0047-6374(79)90111-8
Autor:
Robert A. Menzies, Bernard L. Strehler, R. Kutsky, Richard A. Nordgren, M. Gee, Gerald P. Hirsch
Publikováno v:
Experimental Gerontology. 4:27-32
The existence of long-lived lipid components in developing mice has been demonstrated through the use of separate 14 C and 3 H acetate injections followed by the measurement of residual labels in the five months following injection. Brain and muscle,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decf10c052fcca8cba761919b43d3ddc
https://doi.org/10.1016/0531-5565(69)90023-0
https://doi.org/10.1016/0531-5565(69)90023-0
Autor:
Robert A. Menzies, Bernard L. Strehler, Gerald P. Hirsch, D.D. Hendley, R. Kutsky, Richard A. Nordgren
Publikováno v:
Experimental Gerontology. 4:7-16
1. 1. Four mice were injected at 15 days of age with 14 C leucine; 10–22 weeks later they were injected with 3 H leucine. After the lapse of an additional 4–7 weeks, the animals were sacrificed and ten of their tissues were fractionated into mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94868ddbad98f0c76cfcf2c5bfe53fde
https://doi.org/10.1016/0531-5565(69)90021-7
https://doi.org/10.1016/0531-5565(69)90021-7
Autor:
Gerald P. Hirsch, Bernard L. Strehler
Publikováno v:
Mechanisms of Ageing and Development. 2:237-244
The capacity of synthetases in the supernatant of kidney and liver homogenates to produce soluble protein under the influence of reticulocyte messages and ribosomes was measured in a supernatant- (synthetase-) dependent system obtained by pelleting r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f212686ebf343bf91dd50dbb5f0648
https://doi.org/10.1016/0047-6374(73)90020-1
https://doi.org/10.1016/0047-6374(73)90020-1
Autor:
Gerald P. Hirsch, Bernard L. Strehler
Publikováno v:
Mechanisms of Ageing and Development. 2:229-235
Experiments designed to test the theory that translational modulation is a major agent in the control of development have been conducted. These experiments employed a cell-free hemoglobin synthesizing system derived from rabbit reticulocytes. Compari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0ee2ee61879fa62f87d08ada58a772
https://doi.org/10.1016/0047-6374(73)90019-5
https://doi.org/10.1016/0047-6374(73)90019-5
Publikováno v:
Mechanisms of Ageing and Development. 1:373-385
The nuclear fractions from all the tissues examined contained substantial amounts of protein label possessing quite high relative isotope-retention values. Since several histones are lysine rich and turn over slowly, this is not suprising. Except for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::807520714089d2203cfdd5b5198edc72
https://doi.org/10.1016/0047-6374(72)90082-6
https://doi.org/10.1016/0047-6374(72)90082-6
Publikováno v:
Histological Atlas of the Laboratory Mouse ISBN: 9781461357018
There are two kinds of ossification, endochondral and membranous, implying the presence or absence of a prior cartilaginous model. In both processes bone is formed by osteoblasts, which originate from mesenchyme. Osteoblasts are spindleshaped to colu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8cef72afee2b0dba72b9018e86998c2
https://doi.org/10.1007/978-1-4615-1743-6_11
https://doi.org/10.1007/978-1-4615-1743-6_11
Publikováno v:
Histological Atlas of the Laboratory Mouse ISBN: 9781461357018
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a997265c3ffa45e8a8e152cae98a509
https://doi.org/10.1007/978-1-4615-1743-6_13
https://doi.org/10.1007/978-1-4615-1743-6_13
Publikováno v:
Histological Atlas of the Laboratory Mouse ISBN: 9781461357018
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::220f0516ae2b3a777fdeb5f88463c21f
https://doi.org/10.1007/978-1-4615-1743-6_16
https://doi.org/10.1007/978-1-4615-1743-6_16