Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gerald Nepom"'
Autor:
Erin M. Witkop, Kirsten Diggins, Alice Wiedeman, Elisavet Serti, Gerald Nepom, Vivian H. Gersuk, Bryce Fuchs, S. Alice Long, Peter S. Linsley
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Distinct Natural Killer (NK)-like CD57+ and PD-1+ CD8+ exhausted-like T cell populations (Tex) have both been linked to beneficial immunotherapy response in autoimmune type 1 diabetes (T1D) patients. The origins and relationships between the
Externí odkaz:
https://doaj.org/article/8d3fb1a37da44494b3b4cd1c67e7d55e
Autor:
Kirsten E. Diggins, Elisavet Serti, Virginia Muir, Mario Rosasco, TingTing Lu, Elisa Balmas, Gerald Nepom, S. Alice Long, Peter S. Linsley
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Clinical trials of biologic therapies in type 1 diabetes (T1D) aim to mitigate autoimmune destruction of pancreatic β cells through immune perturbation and serve as resources to elucidate immunological mechanisms in health and disease. In the T1DAL
Externí odkaz:
https://doaj.org/article/37b23ff4286140899c19dfc035864cd1
Autor:
Ghanashyam Sarikonda, Sowbarnika Sachithanantham, Yulia Manenkova, Tinalyn Kupfer, Amanda Posgai, Clive Wasserfall, Philip Bernstein, Laura Straub, Philippe P Pagni, Darius Schneider, Teresa Rodriguez Calvo, Marilyne Coulombe, Kevan Herold, Ronald G Gill, Mark Atkinson, Gerald Nepom, Mario Ehlers, Teodora Staeva, Hideki Garren, Lawrence Steinman, Andrew C Chan, Matthias von Herrath
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54712 (2013)
A recent type 1 diabetes (T1D) clinical trial of rituximab (a B cell-depleting anti-CD20 antibody) achieved some therapeutic benefit in preserving C-peptide for a period of approximately nine months in patients with recently diagnosed diabetes. Our p
Externí odkaz:
https://doaj.org/article/de59e6efcbf84a03a25062ac99797d76
Autor:
Michelle Huffaker, Kanika Kanchan, Henry Bahnson, Ingo Ruczinski, Gautam Shankar, Donald Leung, Carolyn Baloh, George Du Toit, Gideon Lack, Gerald Nepom, Rasika Mathias
Publikováno v:
Journal of Allergy and Clinical Immunology. 149:AB314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12998ff0c05addb16642ac8fe2ca4e4c
https://doi.org/10.1016/j.jaci.2021.12.007
https://doi.org/10.1016/j.jaci.2021.12.007
Autor:
Kanika Kanchan, Gautam Shankar, Michelle Huffaker, Henry Bahnson, R Sharon Chinthrajah, Srinath Sanda, Monali Manohar, George Du Toit, Ingo Ruczinski, Gideon Lack, Kari Nadeau, Stacie Jones, Gerald Nepom, Rasika Mathias
Publikováno v:
Journal of Allergy and Clinical Immunology. 149:AB314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77ccbb6ec28c2b33e2c90c0ede90a28f
https://doi.org/10.1016/j.jaci.2021.12.008
https://doi.org/10.1016/j.jaci.2021.12.008
Autor:
Omri, Snir, Mary, Rieck, John A, Gebe, Betty B, Yue, Crystal A, Rawlings, Gerald, Nepom, Vivianne, Malmström, Jane H, Buckner
Antibodies toward the citrullinated form of the synovial antigen vimentin are specific for rheumatoid arthritis (RA) and are associated with HLA-DRB1*0401. This suggests that T cells specific for peptides derived from citrullinated vimentin presented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::55f5f262e6b267e4f288e960128f8504
https://europepmc.org/articles/PMC3174345/
https://europepmc.org/articles/PMC3174345/
Autor:
Gerald Nepom
Publikováno v:
Diabetes. 39:1153-1157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87e256597489cb03d1750500984c512f
https://doi.org/10.2337/diabetes.39.10.1153
https://doi.org/10.2337/diabetes.39.10.1153
Autor:
I-Ting Chow, Theresa Gates, John McGinty, Duy Mai, George Papadopoulos, Nadia Torres-Chinn, Eddie James, Carla Greenbaum, Gerald Nepom, William Kwok
Publikováno v:
The Journal of Immunology. 194:121.19-121.19
Major histocompatibility complex (MHC) genes, also known as human leukocyte antigen (HLA) genes in humans, are the prevailing risk factors in multiple autoimmune diseases, including multiple sclerosis (MS), autoimmune diabetes (type 1 diabetes or T1D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd38f72d1136db0ea2fc06d25cf1dee
https://doi.org/10.4049/jimmunol.194.supp.121.19
https://doi.org/10.4049/jimmunol.194.supp.121.19
Publikováno v:
The Journal of rheumatology. 31(6)
To compare changes in the computerized measurement of radiographic hand joint space width (JSW) to changes in modified Sharp scores in a retrospective 2-year study of early rheumatoid arthritis (RA).First and last standard clinical hand radiographs o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e25c99d67a1dbcd36f42c0260afa33d
https://pubmed.ncbi.nlm.nih.gov/15170915
https://pubmed.ncbi.nlm.nih.gov/15170915
Autor:
Ronald Bontrop, Manfred Ballas, Alejandro Madrigal, Pierre Hermans, Susan Fuggle, Ńel Otting, Christine Carter, Steven Sacks, Cecile Kaplan, Marie-Christine Morel, Susan F. Radka, Barbara Nepom, Laurine Bow, Ernette Du Toit, Stephanie Crawford, Nan Knitter-Jack, Gerald Nepom, Maria Christina Mazzilli, Zacharie Brahmi, Dominique Charron
Publikováno v:
Immunobiology of HLA ISBN: 9781461281542
Three DR9 cell lines were examined in the Workshop study: DKB, HID, and KT12. Serologic typing in the Workshop indicates that only DKB is completely homozygous throughout the HLA region. KT12 is clearly not consanguinous, being heterozygous at the A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2f0029836c01ce26e597d261fca572d
https://doi.org/10.1007/978-1-4612-3552-1_89
https://doi.org/10.1007/978-1-4612-3552-1_89