Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gerald N. Levy"'
Autor:
Gerald N. Levy
Publikováno v:
Science. 275:1861-1865
Recent letters ( 6 Dec., p. 1593 ; 24 Jan., p. 461 ) have proposed strict rules for co-authorship of scientific publications. I wholeheartedly agree that to put one's name on a paper is an assurance to the scientific community that one has contribute
Autor:
Gerald N. Levy
Publikováno v:
The FASEB Journal. 11:234-247
Members of the structurally diverse class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs) have the ability to prevent or reduce the occurrence of colorectal, certain other gastrointestinal, and perhaps other cancers. The anticarcinoge
Publikováno v:
Cancer Letters. 111:39-50
N-Acetyltransferase activity and Michaelis-Menten kinetic constants were determined in cancerous and non-cancerous breast tissues from 30 female patients with breast cancer. The results derived from tissue cytosol showed that 12 rapid, ten intermedia
Publikováno v:
Biochemical and Biophysical Research Communications. 215:346-354
Prostaglandin endoperoxide H synthase is the key enzyme in the conversion of arachidonic acid to tissue prostanoids. Two isoforms of prostaglandin endoperoxide H synthase have been identified: PHS-1 is constitutively expressed in most tissues under n
Publikováno v:
Pharmacogenetics. 3:71-76
The increased risk of rapid acetylator humans for the development of colorectal cancer has created interest in experimental animal models to study the relationship of N-acetyltransferase phenotype to colon cancer. Colon cytosols from inbred mouse lin
Autor:
GERALD N. LEVY
Publikováno v:
Toxicological Sciences. 21:23-30
Publikováno v:
Pharmacogenetics. 2:197-206
Over the past 10 years, much fascinating information has been obtained concerning the biochemistry, genetics, toxicological implications and molecular genetics of the N-acetylation polymorphism in mice. Using C57BL/6J (B6) mice as representative of r
Autor:
Wendell W. Weber, Gerald N. Levy
Publikováno v:
Carcinogenesis. 13:159-164
Formation of urinary bladder DNA-2-aminofluorene adducts in inbred and acetylator congenic mice was measured 3 h after a 60 mg/kg dose of the arylamine carcinogen. The sensitivity of 32P-postlabeling with HPLC analysis permitted quantitation of adduc
Autor:
Gerald N. Levy, Hassan R. Dhaini
Publikováno v:
Pharmacogenetics. 10(1)
The frequency distributions of human N-acetyltransferase 1 (NAT1 * ) alleles in various ethnic groups are largely unknown. This lack of information is in contrast to the many studies of ethnic differences in NAT2 * alleles and phenotypes. Increasing