Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Gerald L. Kramer"'
Autor:
Helene Wolleb, Seiji Ogawa, Robert W. Haley, Erick M. Carreira, Junhui Xiao, Diana M. Shih, Christian Ebner, John F. Teiber, Gerald L. Kramer
Publikováno v:
Biochemical and Biophysical Research Communications. 505:87-92
The mammalian paraoxonases (PONs 1, 2 and 3) are a family of esterases that are highly conserved within and between species. They exhibit antioxidant and anti-inflammatory activities. However, their physiological function(s) and native substrates are
Autor:
Petra Wilgenbus, Marion Goldeck, Sebastian Altenhöfer, Puneet K. Chowdhary, John F. Teiber, Donovan C. Haines, Gerald L. Kramer, Ulrich Förstermann, Junhui Xiao, Ines Witte, Sven Horke, Robert W. Haley
Publikováno v:
Biochemical Journal. 426:73-83
Two virulence factors produced by Pseudomonas aeruginosa are pyocyanin and N-(3-oxododecanoyl)-L-homoserine lactone (3OC12). Pyocyanin damages host cells by generating ROS (reactive oxygen species). 3OC12 is a quorum-sensing signalling molecule which
Publikováno v:
Circulation. 132
Introduction: A recent study in clinic patients found serum activity of the anti-oxidative, anti-inflammatory HDL-associated enzyme paraoxonase 1 (PON1) inversely associated with plasma brain natriuretic peptide (BNP), a marker of heart failure, and
Autor:
Ines Witte, Eva Schütz, Moritz Selbach, Gerald L. Kramer, Sven Horke, John F. Teiber, Junhui Xiao, Petra Wilgenbus
Pseudomonas aeruginosa produces N -(3-oxo-dodecanoyl)- l -homoserine lactone (3OC12), a crucial signaling molecule that elicits diverse biological responses in host cells thought to subvert immune defenses. The mechanism mediating many of these respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c0a8cf10fbb7252dadf9240af9e44b
https://europepmc.org/articles/PMC4534671/
https://europepmc.org/articles/PMC4534671/
Publikováno v:
Journal of Surgical Research. 129:272-277
Background Plasma angiotensin II (ANG II) is not increased significantly in renovascular hypertension (RVH), but tissue ANG II levels are elevated in both kidneys of renovascular rats. Because the contralateral, non-ischemic kidney is critical for ma
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 26:639-645
(1) Disturbances of mesolimbic and mesocortical dopamine (DA) function have been implicated in the pathophysiology of several psychiatric disorders, including major depressive disorder. (2) Utilizing the learned helplessness (LH) animal model of clin
Autor:
Frederick Petty, Rebecca Ahlbrand, Laurel M. Pritchard, Neil M. Richtand, Floyd R. Sallee, Danzhao Wang, Rebecca H Spitzer, James P. Herman, Gerald L. Kramer
Publikováno v:
The Journal of Neuroscience. 21:9027-9035
Behavioral sensitization to psychostimulants involves neuroadaptation of stress-responsive systems. We have identified and sequenced a glucocorticoid-induced receptor (GIR) cDNA from rat prefrontal cortex. The full-length GIR cDNA encodes a 422 amino
Autor:
Jason Worchel, Lori L. Davis, A L Teten, R C Stone, Keith A. Young, J. H. Casada, Frederick Petty, S. K. Brannan, V Gajewski, Gerald L. Kramer
Publikováno v:
International Clinical Psychopharmacology. 16:331-337
Post-traumatic stress disorder (PTSD) is a common and increasingly diagnosed mental illness. Recent pharmacotherapeutic research on treatments for this condition has focused on antidepressant drugs with serotonergic actions. However, the presence of
Autor:
Frederick Petty, Martin Kram, Gerald L. Kramer, James M. Bjork, Alina M Suris, A. John Rush, F. Gerard Moeller
Publikováno v:
Psychiatry Research. 101:131-136
Plasma gamma-aminobutyric acid (GABA) levels are decreased in some patients with depression, mania and alcoholism. Medications which increase plasma GABA improve symptoms of mood disorders and can decrease aggression. We examined the relationship bet
Publikováno v:
Neuroscience Research. 38:193-198
GABA is involved in both clinical depression and in animal models of depression; however, the roles of GABA(A) and GABA(B) receptors in specific brain regions are not clear. Changes in densities of both GABA(A) and GABA(B) receptors have been reporte