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pro vyhledávání: '"Gerald J. Berry, MD"'
Phase II Trial of Regorafenib and Oral Methotrexate in Previously Treated Advanced KRAS-Mutant NSCLC
Autor:
Jacqueline V. Aredo, MD, MS, Heather A. Wakelee, MD, Kavitha J. Ramchandran, MD, Joel W. Neal, MD, PhD, Maximilian Diehn, MD, PhD, Angela Bik-Yu Hui, PhD, Ameen Salahudeen, MD, PhD, Bernice Kwong, MD, Gerald J. Berry, MD, H. Henry Guo, MD, PhD, Kristen Cunanan, PhD, Shireen Vali, PhD, Danny Pancirer, BA, Vivian Tsang, MSN, Grace Hwang, MS, Monica Loza, BA, Brittany Johnson, BA, Isabelle Blanchard, BS, Sukhmani K. Padda, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 12, Pp 100741- (2024)
Introduction: There are no standard targeted treatment options for advanced KRAS-mutant NSCLC beyond KRAS G12C inhibitors. A computational model identified regorafenib and low-dose methotrexate as synergistic in preclinical models of KRAS-mutant NSCL
Externí odkaz:
https://doaj.org/article/568d1ca40dcd476cba01bc859c5cbee5
