Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Gerald J. Berry"'
Phase II Trial of Regorafenib and Oral Methotrexate in Previously Treated Advanced KRAS-Mutant NSCLC
Autor:
Jacqueline V. Aredo, MD, MS, Heather A. Wakelee, MD, Kavitha J. Ramchandran, MD, Joel W. Neal, MD, PhD, Maximilian Diehn, MD, PhD, Angela Bik-Yu Hui, PhD, Ameen Salahudeen, MD, PhD, Bernice Kwong, MD, Gerald J. Berry, MD, H. Henry Guo, MD, PhD, Kristen Cunanan, PhD, Shireen Vali, PhD, Danny Pancirer, BA, Vivian Tsang, MSN, Grace Hwang, MS, Monica Loza, BA, Brittany Johnson, BA, Isabelle Blanchard, BS, Sukhmani K. Padda, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 12, Pp 100741- (2024)
Introduction: There are no standard targeted treatment options for advanced KRAS-mutant NSCLC beyond KRAS G12C inhibitors. A computational model identified regorafenib and low-dose methotrexate as synergistic in preclinical models of KRAS-mutant NSCL
Externí odkaz:
https://doaj.org/article/568d1ca40dcd476cba01bc859c5cbee5
Publikováno v:
Surgeries, Vol 4, Iss 2, Pp 275-282 (2023)
Amyloidosis is a rare disease characterized by the accumulation of misfolded extracellular proteins in various organs. Over 30 precursor proteins have been identified that can form amyloid deposits in different parts of the body. The most frequently
Externí odkaz:
https://doaj.org/article/3b0a286237b64cf4b325afee5c42b022
Autor:
Amirhossein Kiani, Bora Uyumazturk, Pranav Rajpurkar, Alex Wang, Rebecca Gao, Erik Jones, Yifan Yu, Curtis P. Langlotz, Robyn L. Ball, Thomas J. Montine, Brock A. Martin, Gerald J. Berry, Michael G. Ozawa, Florette K. Hazard, Ryanne A. Brown, Simon B. Chen, Mona Wood, Libby S. Allard, Lourdes Ylagan, Andrew Y. Ng, Jeanne Shen
Publikováno v:
npj Digital Medicine, Vol 3, Iss 1, Pp 1-8 (2020)
Abstract Artificial intelligence (AI) algorithms continue to rival human performance on a variety of clinical tasks, while their actual impact on human diagnosticians, when incorporated into clinical workflows, remains relatively unexplored. In this
Externí odkaz:
https://doaj.org/article/615de5de8f5543b69db4c81e88e47231
Autor:
Ke Jin, Simon Parreau, Kenneth J. Warrington, Matthew J. Koster, Gerald J. Berry, Jörg J. Goronzy, Cornelia M. Weyand
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Blood vessels are indispensable for host survival and are protected from inappropriate inflammation by immune privilege. This protection is lost in patients with autoimmune vasculitides, a heterogeneous group of diseases causing damage to arteries, a
Externí odkaz:
https://doaj.org/article/d91110e59a8c404d85ef428bdabfd561
Autor:
Sean Agbor-Enoh, Yan Wang, Ilker Tunc, Moon Kyoo Jang, Andrew Davis, Iwijn De Vlaminck, Helen Luikart, Pali D. Shah, Irina Timofte, Anne W. Brown, Argit Marishta, Kenneth Bhatti, Sasha Gorham, Ulgen Fideli, Jennifer Wylie, David Grimm, Natalie Goodwin, Yanqin Yang, Kapil Patel, Jun Zhu, Aldo Iacono, Jonathan B. Orens, Steven D. Nathan, Charles Marboe, Gerald J. Berry, Stephen R. Quake, Kiran Khush, Hannah A. Valantine
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 541-553 (2019)
Background: Allograft failure is common in lung-transplant recipients and leads to poor outcomes including early death. No reliable clinical tools exist to identify patients at high risk for allograft failure. This study tested the use of donor-deriv
Externí odkaz:
https://doaj.org/article/f9d8f23efeb045e280d2635633975eac
Autor:
Jingtao Qiu, Bowen Wu, Stuart B. Goodman, Gerald J. Berry, Jorg J. Goronzy, Cornelia M. Weyand
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Like other autoimmune diseases, rheumatoid arthritis (RA) develops in distinct stages, with each phase of disease linked to immune cell dysfunction. HLA class II genes confer the strongest genetic risk to develop RA. They encode for molecules essenti
Externí odkaz:
https://doaj.org/article/86d72c2e66b644d88963f2078026ac44
Autor:
Mitsuhiro Akiyama, Shozo Ohtsuki, Gerald J. Berry, David H. Liang, Jörg J. Goronzy, Cornelia M. Weyand
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Autoimmune diseases can afflict every organ system, including blood vessels that are critically important for host survival. The most frequent autoimmune vasculitis is giant cell arteritis (GCA), which causes aggressive wall inflammation in medium an
Externí odkaz:
https://doaj.org/article/f136914fbfff452a832614a824841226
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Autoimmune and autoinflammatory diseases of the medium and large arteries, including the aorta, cause life-threatening complications due to vessel wall destruction but also by wall remodeling, such as the formation of wall-penetrating microvessels an
Externí odkaz:
https://doaj.org/article/c28c5f99c63e4a42bb4d0b8c647a0e49
Autor:
Mitsuhiro Akiyama, Markus Zeisbrich, Nour Ibrahim, Shozo Ohtsuki, Gerald J. Berry, Peter H. Hwang, Jörg J. Goronzy, Cornelia M. Weyand
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Objective: Granulomatosis with polyangiitis (GPA) is a multi-organ vasculitic syndrome typically associated with neutrophil extracellular trap (NET) formation and aggressive tissue inflammation. Manifestations in head and neck (H&N) GPA include septa
Externí odkaz:
https://doaj.org/article/16c530416e3e45dab91acb50d3508ee8
Autor:
Kun-Hsing Yu, Ce Zhang, Gerald J. Berry, Russ B. Altman, Christopher Ré, Daniel L. Rubin, Michael Snyder
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Diagnosis of lung cancer through manual histopathology evaluation is insufficient to predict patient survival. Here, the authors use computerized image processing to identify diagnostically relevant image features and use these features to distinguis
Externí odkaz:
https://doaj.org/article/412254c245364c069c2a4448a132d6dd