Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Gerald J Obermair"'
Autor:
Pierre Coste de Bagneaux, Leonie von Elsner, Tatjana Bierhals, Marta Campiglio, Jessika Johannsen, Gerald J Obermair, Maja Hempel, Bernhard E Flucher, Kerstin Kutsche
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008625 (2020)
P/Q-type channels are the principal presynaptic calcium channels in brain functioning in neurotransmitter release. They are composed of the pore-forming CaV2.1 α1 subunit and the auxiliary α2δ-2 and β4 subunits. β4 is encoded by CACNB4, and its
Externí odkaz:
https://doaj.org/article/c050a185b2ed4033bb261d10262558d5
Autor:
Agnieszka Witalisz-Siepracka, Clio-Melina Denk, Bernhard Zdársky, Lorenz Hofmann, Sophie Edtmayer, Theresa Harm, Stefanie Weiss, Kerstin Heindl, Manuel Hessenberger, Sabrina Summer, Sayantanee Dutta, Emilio Casanova, Gerald J. Obermair, Balázs Győrffy, Eva Maria Putz, Heinz Sill, Dagmar Stoiber
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Acute myeloid leukemia (AML) is a heterogenous disease characterized by the clonal expansion of myeloid progenitor cells. Despite recent advancements in the treatment of AML, relapse still remains a significant challenge, necessitating the developmen
Externí odkaz:
https://doaj.org/article/cf2694443fe34e35bace14518f251243
Autor:
Cornelia Ablinger, Clarissa Eibl, Stefanie M. Geisler, Marta Campiglio, Gary J. Stephens, Markus Missler, Gerald J. Obermair
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9885 (2022)
The α2δ auxiliary subunits of voltage-gated calcium channels (VGCC) were traditionally regarded as modulators of biophysical channel properties. In recent years, channel-independent functions of these subunits, such as involvement in synapse format
Externí odkaz:
https://doaj.org/article/df8398627e2e4395b71c9413d188c651
Autor:
Stefanie M. Geisler, Ariane Benedetti, Clemens L. Schöpf, Christoph Schwarzer, Nadia Stefanova, Arnold Schwartz, Gerald J. Obermair
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
Auxiliary α2δ subunits of voltage-gated calcium channels modulate channel trafficking, current properties, and synapse formation. Three of the four isoforms (α2δ-1, α2δ-2, and α2δ-3) are abundantly expressed in the brain; however, of the avai
Externí odkaz:
https://doaj.org/article/d2b32c38d2aa49d4a435cf75dc520dda
Autor:
Friederike Stephani, Veronika Scheuer, Tobias Eckrich, Kerstin Blum, Wenying Wang, Gerald J. Obermair, Jutta Engel
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Voltage-gated Ca2+ channels are composed of a pore-forming α1 subunit and auxiliary β and α2δ subunits, which modulate Ca2+ current properties and channel trafficking. So far, the partial redundancy and specificity of α1 for α2δ subunits in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52350c83633b6c55e53a87e0ff9d4c7
Publikováno v:
Handbook of experimental pharmacology.
α
Autor:
Cornelia, Ablinger, Clarissa, Eibl, Stefanie M, Geisler, Marta, Campiglio, Gary J, Stephens, Markus, Missler, Gerald J, Obermair
Publikováno v:
International journal of molecular sciences. 23(17)
The α
Stabilization of negative activation voltages of Cav1.3 L-Type Ca2+-channels by alternative splicing
Autor:
Alexandra Pinggera, Jörg Striessnig, Petronel Tuluc, Nadja T. Hofer, Yuliia V. Nikonishyna, Gerald J. Obermair, Eva Maria Fritz
Publikováno v:
Channels
article-version (VoR) Version of Record
article-version (VoR) Version of Record
>Low voltage-activated Cav1.3 L-type Ca2+-channels are key regulators of neuronal excitability controlling neuronal development and different types of learning and memory. Their physiological functions are enabled by their negative activation voltage
Autor:
Annette C. Dolphin, Gerald J. Obermair
Publikováno v:
Voltage-Gated Calcium Channels ISBN: 9783031088803
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::456e6e9123d78f43a1567316b4ded55a
https://doi.org/10.1007/978-3-031-08881-0_5
https://doi.org/10.1007/978-3-031-08881-0_5