Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gerald Hebbink"'
Publikováno v:
International Dairy Journal. 72:1-13
Conventional lactose crystallisations give large spans that are not suitable for direct use in inhaler grade lactose. The factors causing large spans are successive nucleation events and growth rate dispersion. This paper (Part 1 of 2) explores a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95a4e2055679b2a7b367354db0e6649d
https://doi.org/10.1016/j.idairyj.2017.03.014
https://doi.org/10.1016/j.idairyj.2017.03.014
Publikováno v:
International Dairy Journal. 72:14-22
This paper (Part 2 of 2) revises and expands on the original model for the laminar flow continuous settling crystalliser presented in Part 1 in an effort to understand why the original model over-predicted product particle d 10 and d 50 and under-pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0d49ec43edcd266ceb4e792549e3e77
https://doi.org/10.1016/j.idairyj.2017.03.015
https://doi.org/10.1016/j.idairyj.2017.03.015
Publikováno v:
International Dairy Journal. 61:148-154
This paper describes two methods used to produce a constant supply of super-saturated lactose solution with nuclei already present, required as the feed stream for a new design of a continuous crystalliser. Both methods involve cooling a hot saturate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5cb65dbd96ead45a8fecebd1bc9ea8
https://doi.org/10.1016/j.idairyj.2016.06.001
https://doi.org/10.1016/j.idairyj.2016.06.001
Publikováno v:
AAPS PharmSciTech, 2014, Vol.15(4), pp.898-909 [Peer Reviewed Journal]
The effect of milled and micronized lactose fines on the fluidization and in vitro aerosolization properties of dry powder inhaler (DPI) formulations was investigated, and the suitability of static and dynamic methods for characterizing general powde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0e0eabd1485bb43be21d5693cbed6d
https://doi.org/10.1208/s12249-014-0119-6
https://doi.org/10.1208/s12249-014-0119-6
Publikováno v:
International journal of pharmaceutics, 2015, Vol.478(1), pp.53-59 [Peer Reviewed Journal]
The aim of the study was to investigate how the fine particle content of lactose carriers prepared with different types of lactose fines regulates dry powder inhaler (DPI) formulation performance of a cohesive batch of micronised budesonide. Budesoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6776f0f2eabb2d076051a7e75e8a1cac
Publikováno v:
AAPS PharmSciTech, 2014, Vol.15(4), pp.1009-1020 [Peer Reviewed Journal]
The study aimed to establish a function-based relationship between the physical and bulk properties of pre-blended mixtures of fine and coarse lactose grades with the in vitro performance of an adhesive active pharmaceutical ingredient (API). Differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fcaccd3000140ba33840b09a682397
Autor:
David Alexander Vodden Morton, Philip Leslie, Jonathan Parks, Ruth Howell, Laurence Orlando, Louise Ho, Ian Larson, Sally Sim, Gerald Hebbink, Kenneth Margo
Publikováno v:
International journal of pharmaceutics. 477(1-2)
This study aims to improve understanding of the powder fluidisation and aerosolisation processes unique to a split capsule dry powder inhaler. It uses a combination of dynamic real-time methods and a suite of powder material physicochemical character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30a9325ee6341c620729eefde3bb4c2
https://pubmed.ncbi.nlm.nih.gov/25196720
https://pubmed.ncbi.nlm.nih.gov/25196720
Publikováno v:
International journal of pharmaceutics. 395(1-2)
Alpha-lactose monohydrate is widely used as an excipient in dry powder inhalers, and plays a very important role in the efficiency of the drug delivery. Due to the processing, low levels of amorphous lactose could be present in the blends. Varying am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829237accd3148fa3ddfe8661bfd3b67
https://pubmed.ncbi.nlm.nih.gov/20493937
https://pubmed.ncbi.nlm.nih.gov/20493937