Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Gerald H. Learn"'
Autor:
Simone Joas, Erica H. Parrish, Clement W. Gnanadurai, Edina Lump, Christina M. Stürzel, Nicholas F. Parrish, Gerald H. Learn, Ulrike Sauermann, Berit Neumann, Kerstin Mätz Rensing, Dietmar Fuchs, James M. Billingsley, Steven E. Bosinger, Guido Silvestri, Cristian Apetrei, Nicolas Huot, Thalia Garcia-Tellez, Michaela Müller-Trutwin, Dominik Hotter, Daniel Sauter, Christiane Stahl-Hennig, Beatrice H. Hahn, Frank Kirchhoff
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
In contrast to HIV, simian immunodeficiency viruses (SIV) do not cause disease in their hosts, and the reasons for this are unclear. Here, Joas et al. incorporate two putative HIV virulence factors into SIV and study effects in infected monkeys, sugg
Externí odkaz:
https://doaj.org/article/6b840246338c48ae857ef8de0672d11d
Autor:
Weimin Liu, Scott Sherrill-Mix, Gerald H. Learn, Erik J. Scully, Yingying Li, Alexa N. Avitto, Dorothy E. Loy, Abigail P. Lauder, Sesh A. Sundararaman, Lindsey J. Plenderleith, Jean-Bosco N. Ndjango, Alexander V. Georgiev, Steve Ahuka-Mundeke, Martine Peeters, Paco Bertolani, Jef Dupain, Cintia Garai, John A. Hart, Terese B. Hart, George M. Shaw, Paul M. Sharp, Beatrice H. Hahn
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Unlike chimpanzees and gorillas, bonobos have not been found infected by malaria parasites in the wild. Here, Liu et al. report more thorough survey and sequencing results showing that bonobos host malaria parasites, including a yet-unknown species,
Externí odkaz:
https://doaj.org/article/dcde71d74a4544ac9856a87833ed478f
Autor:
Hannah J. Barbian, Raven Jackson-Jewett, Corrine S. Brown, Frederic Bibollet-Ruche, Gerald H. Learn, Timothy Decker, Edward F. Kreider, Yingying Li, Thomas N. Denny, Paul M. Sharp, George M. Shaw, Jeffrey Lifson, Edward P. Acosta, Michael S. Saag, Katharine J. Bar, Beatrice H. Hahn
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-9 (2017)
Abstract Background Simian immunodeficiency virus of chimpanzees (SIVcpz), the progenitor of human immunodeficiency virus type 1 (HIV-1), is associated with increased mortality and AIDS-like immunopathology in wild-living chimpanzees (Pan troglodytes
Externí odkaz:
https://doaj.org/article/bf0abb6d568143e1b7703f0c76b02a89
Autor:
Jesus F. Salazar-Gonzalez, Maria G. Salazar, Damien C. Tully, Colin B. Ogilvie, Gerald H. Learn, Todd M. Allen, Sonya L. Heath, Paul Goepfert, Katharine J. Bar
Publikováno v:
Pathogens and Immunity, Vol 1, Iss 1, Pp 129-153 (2016)
Background: Identification of HIV-1 genomes responsible for establishing clinical infection in newly infected individuals is fundamental to prevention and pathogenesis research. Processing, storage, and transportation of the clinical samples required
Externí odkaz:
https://doaj.org/article/20a0750d959c48bebba271075a3c1a63
Autor:
Sesh A. Sundararaman, Lindsey J. Plenderleith, Weimin Liu, Dorothy E. Loy, Gerald H. Learn, Yingying Li, Katharina S. Shaw, Ahidjo Ayouba, Martine Peeters, Sheri Speede, George M. Shaw, Frederic D. Bushman, Dustin Brisson, Julian C. Rayner, Paul M. Sharp, Beatrice H. Hahn
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
African apes harbour six Plasmodium species, one of which gave rise to the human malaria parasite. Here, Sundaraman et al. use selective whole-genome amplification to determine genome sequences from two chimpanzee Plasmodiumspecies, shedding light on
Externí odkaz:
https://doaj.org/article/e0e6274d383b4d74a1b7fd1cd8a493cc
Autor:
Kshitij Wagh, Edward F. Kreider, Yingying Li, Hannah J. Barbian, Gerald H. Learn, Elena Giorgi, Peter T. Hraber, Timothy G. Decker, Andrew G. Smith, Marcos V. Gondim, Lindsey Gillis, Jamie Wandzilak, Gwo-Yu Chuang, Reda Rawi, Fangping Cai, Pierre Pellegrino, Ian Williams, Julie Overbaugh, Feng Gao, Peter D. Kwong, Barton F. Haynes, George M. Shaw, Persephone Borrow, Michael S. Seaman, Beatrice H. Hahn, Bette Korber
Publikováno v:
Cell Reports, Vol 25, Iss 4, Pp 893-908.e7 (2018)
Summary: Densely arranged N-linked glycans shield the HIV-1 envelope (Env) trimer from antibody recognition. Strain-specific breaches in this shield (glycan holes) can be targets of vaccine-induced neutralizing antibodies that lack breadth. To unders
Externí odkaz:
https://doaj.org/article/263741a4aea942aabfd534e4a17be6c2
Autor:
Lindsey J. Plenderleith, Weimin Liu, Oscar A. MacLean, Yingying Li, Dorothy E. Loy, Sesh A. Sundararaman, Frederic Bibollet-Ruche, Gerald H. Learn, Beatrice H. Hahn, Paul M. Sharp
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
Externí odkaz:
https://doaj.org/article/0d415e6603a54ed2aaf1982ee6281271
Autor:
Lindsey J. Plenderleith, Weimin Liu, Oscar A. MacLean, Yingying Li, Dorothy E. Loy, Sesh A. Sundararaman, Frederic Bibollet-Ruche, Gerald H. Learn, Beatrice H. Hahn, Paul M. Sharp
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Plasmodium falciparum, the major cause of malaria morbidity and mortality in humans, has been shown to have emerged after cross-species transmission of one of six host-specific parasites (subgenus Laverania) infecting wild chimpanzees (Pan t
Externí odkaz:
https://doaj.org/article/72968de674554b908ed14642623310d4
Autor:
Peter Hraber, Bette Korber, Kshitij Wagh, Elena E. Giorgi, Tanmoy Bhattacharya, S. Gnanakaran, Alan S. Lapedes, Gerald H. Learn, Edward F. Kreider, Yingying Li, George M. Shaw, Beatrice H. Hahn, David C. Montefiori, S. Munir Alam, Mattia Bonsignori, M. Anthony Moody, Hua-Xin Liao, Feng Gao, Barton F. Haynes
Publikováno v:
Viruses, Vol 7, Iss 10, Pp 5443-5475 (2015)
Within-host genetic sequencing from samples collected over time provides a dynamic view of how viruses evade host immunity. Immune-driven mutations might stimulate neutralization breadth by selecting antibodies adapted to cycles of immune escape that
Externí odkaz:
https://doaj.org/article/cefd2f81274f40d19b1c54ff5cc382fd
Autor:
Alex K Piel, Fiona A Stewart, Lilian Pintea, Yingying Li, Miguel A Ramirez, Dorothy E Loy, Patricia A Crystal, Gerald H Learn, Leslie A Knapp, Paul M Sharp, Beatrice H Hahn
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182723 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0058965.].
Externí odkaz:
https://doaj.org/article/5e8c188897fe49b9a37ec8e9bb51572c