Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Gerald G, Krueger"'
Autor:
Matthew T. Patrick, Philip E. Stuart, Kalpana Raja, Johann E. Gudjonsson, Trilokraj Tejasvi, Jingjing Yang, Vinod Chandran, Sayantan Das, Kristina Callis-Duffin, Eva Ellinghaus, Charlotta Enerbäck, Tõnu Esko, Andre Franke, Hyun M. Kang, Gerald G. Krueger, Henry W. Lim, Proton Rahman, Cheryl F. Rosen, Stephan Weidinger, Michael Weichenthal, Xiaoquan Wen, John J. Voorhees, Gonçalo R. Abecasis, Dafna D. Gladman, Rajan P. Nair, James T. Elder, Lam C. Tsoi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Approximately 30% of psoriasis patients develop psoriatic arthritis (PsA) and early diagnosis is crucial for the management of PsA. Here, Patrick et al. develop a computational pipeline involving statistical and machine-learning methods that can asse
Externí odkaz:
https://doaj.org/article/f67954f1b8fa41a1be488a5ddddc158b
Autor:
Lam C. Tsoi, Philip E. Stuart, Chao Tian, Johann E. Gudjonsson, Sayantan Das, Matthew Zawistowski, Eva Ellinghaus, Jonathan N. Barker, Vinod Chandran, Nick Dand, Kristina Callis Duffin, Charlotta Enerbäck, Tõnu Esko, Andre Franke, Dafna D. Gladman, Per Hoffmann, Külli Kingo, Sulev Kõks, Gerald G. Krueger, Henry W. Lim, Andres Metspalu, Ulrich Mrowietz, Sören Mucha, Proton Rahman, Andre Reis, Trilokraj Tejasvi, Richard Trembath, John J. Voorhees, Stephan Weidinger, Michael Weichenthal, Xiaoquan Wen, Nicholas Eriksson, Hyun M. Kang, David A. Hinds, Rajan P. Nair, Gonçalo R. Abecasis, James T Elder
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Psoriasis is an immune-mediated skin disease with a complex genetic architecture. Here, Elder and colleagues identify 16 novel psoriasis susceptibility loci using GWAS meta-analysis with a combined effective sample size of over 39,000 individuals.
Externí odkaz:
https://doaj.org/article/f7c9d14db1d44c6a865877ade1d17933
Autor:
David R. Berk, Gerald G. Krueger, Kim A. Papp, David M. Pariser, Robert C. Higham, Lynn Navale, Leon H Kircik, Mark Lebwohl, Bruce Strober
Publikováno v:
Dermatology and Therapy
The Psoriasis Area and Severity Index (PASI) is the most widely used clinical measure in clinical trials to assess disease severity of plaque psoriasis. However, the PASI is not a precise measure of severity with less precision when the regional area
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efce8526efa5ffad4d2a2794443fb0a
https://doi.org/10.1007/s13555-021-00572-2
https://doi.org/10.1007/s13555-021-00572-2
Autor:
Iannis E. Adamopoulos, Dario Kivelevitch, Gerald G. Krueger, Richard G. Langley, Alan Menter, So Yeon Paek
Publikováno v:
Dermatology and Therapy
Psoriasis is an immune-mediated inflammatory skin disease associated with numerous inflammatory comorbidities, including increased cardiovascular risk. The interleukin (IL)-23/IL-17 axis plays a central role in the immunopathogenesis of psoriasis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7872d48fa7f2b92718b005595a9cf0d3
https://doi.org/10.1007/s13555-021-00483-2
https://doi.org/10.1007/s13555-021-00483-2
Autor:
Bing Jian Feng, Gerald G. Krueger, Kristina Callis Duffin, Michael Milliken, Jessica A. Walsh, Courtney Carroll, Sophie Belman, Benjamin Haaland
Publikováno v:
J Rheumatol
Objective.Delays in the diagnosis and treatment of psoriatic arthritis (PsA) are common. These delays contribute to impairments in quality of life and joint damage. This study aims to calculate the incidence rate of PsA over time and identify clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70f9fa58f513dbf606f18d850c3653e
https://pubmed.ncbi.nlm.nih.gov/33858978
https://pubmed.ncbi.nlm.nih.gov/33858978
Autor:
Annette Szumski, Kristina Callis Duffin, Heather Jones, Daniel O. Clegg, Jessica A. Walsh, Lotus Mallbris, Gerald G. Krueger
Publikováno v:
Psoriasis: Targets and Therapy
Jessica A Walsh,1 Heather Jones,2 Lotus Mallbris,2 Kristina Callis Duffin,3 Gerald G Krueger,3 Daniel O Clegg,1 Annette Szumski4 1Division of Rheumatology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, US
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3702452fa27ce8a7fa1f477357b08a96
https://doi.org/10.2147/ptt.s169333
https://doi.org/10.2147/ptt.s169333
Autor:
Knut M Wittkowski, Craig Leonardi, Alice Gottlieb, Alan Menter, Gerald G Krueger, Paul W Tebbey, Jennifer Belasco, Razieh Soltani-Arabshahi, John Gray, Liz Horn, James G Krueger, International Psoriasis Council
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20279 (2011)
This study correlated assessment tools for evaluating the severity of skin, nail, and joint symptoms in patients with psoriasis (Pso) and psoriatic arthritis (PsA). Adults with plaque Pso (with or without PsA) were enrolled from four U.S. institution
Externí odkaz:
https://doaj.org/article/ac45086cb532479b918d24f2adb3321d
Autor:
Bing-Jian Feng, Liang-Dan Sun, Razieh Soltani-Arabshahi, Anne M Bowcock, Rajan P Nair, Philip Stuart, James T Elder, Steven J Schrodi, Ann B Begovich, Gonçalo R Abecasis, Xue-Jun Zhang, Kristina P Callis-Duffin, Gerald G Krueger, David E Goldgar
Publikováno v:
PLoS Genetics, Vol 5, Iss 8, p e1000606 (2009)
Psoriasis is a common inflammatory skin disease characterized by thickened scaly red plaques. Previously we have performed a genome-wide association study (GWAS) on psoriasis with 1,359 cases and 1,400 controls, which were genotyped for 447,249 SNPs.
Externí odkaz:
https://doaj.org/article/95dc36b827f84cbcb5024ea686d7a30f
Autor:
Dawn E. Smilek, Gerald G. Krueger, Robert J. Konrad, Anne E. Laumann, Kristina M. Harris, Sandra Garcet, Yolanda R. Helfrich, Kirk Barber, Margie Byron, Robert Bissonnette, Erin E. Boh, Howard Sofen, Pradeepthi Bathala, William T. Barry, Steven R. Feldman, James McNamara, Martin Stengelin, Neil J. Korman, James G. Krueger, Noha Lim
Publikováno v:
JAMA Dermatology. 157:1306
Importance Psoriasis relapse may involve compensatory T-cell activation pathways in the presence of CD28-CD80/CD86 blockade with abatacept. Objective To determine whether costimulatory signaling blockade with abatacept prevents psoriasis relapse afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b44db52a7cbc5affd6863477631290
https://doi.org/10.1001/jamadermatol.2021.3492
https://doi.org/10.1001/jamadermatol.2021.3492
Autor:
Bruce Strober, Lynn Navale, Leon H Kircik, Gerald G. Krueger, Robert C. Higham, Mark Lebwohl, David R. Berk, Kim A. Papp, David M. Pariser
Publikováno v:
Journal of the American Academy of Dermatology. 85:AB164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7779d4f8cceb6e96cdc9bc40e40c975b
https://doi.org/10.1016/j.jaad.2021.06.670
https://doi.org/10.1016/j.jaad.2021.06.670