Zobrazeno 1 - 10
of 313
pro vyhledávání: '"Gerald F Gebhart"'
Autor:
Michael S. Gold, Gerald F. Gebhart
Publikováno v:
The journal of pain. 21(3-4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01efec79f7192e6612f8d3a01e334516
https://pubmed.ncbi.nlm.nih.gov/32771208
https://pubmed.ncbi.nlm.nih.gov/32771208
Publikováno v:
Journal of Urology. 196:892-901
Chronic prostatitis/chronic pelvic pain syndrome causes symptoms that include the frequent and urgent need to urinate, pain or burning during urination and pain radiating to the back, abdomen and/or colorectum. These bladder symptoms suggest that chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e744793b2ee86f91538a5000f1553bc0
https://doi.org/10.1016/j.juro.2016.03.077
https://doi.org/10.1016/j.juro.2016.03.077
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 310:G790-G798
The sensory innervation of the distal colorectum includes mechanically insensitive afferents (MIAs; ∼25%), which acquire mechanosensitivity in persistent visceral hypersensitivity and thus generate de novo input to the central nervous system. We ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc6380196f265f6f1e3f6ce9407737e
https://doi.org/10.1152/ajpgi.00430.2015
https://doi.org/10.1152/ajpgi.00430.2015
Publikováno v:
Neurourology and Urodynamics. 36:286-292
Aims Previous studies have shown that the activin-binding protein follistatin reduces inflammation in several mouse models of colitis. To determine whether follistatin also has a beneficial effect following bladder inflammation, we induced cystitis i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::975c7bf892c35777cabebc18cc562cb7
https://doi.org/10.1002/nau.22941
https://doi.org/10.1002/nau.22941
Publikováno v:
Pain. 159(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170f3e77837d317ad164b32a8d08dc6b
https://pubmed.ncbi.nlm.nih.gov/29384837
https://pubmed.ncbi.nlm.nih.gov/29384837
Publikováno v:
Pain. 156:1537-1544
Chronic nonbacterial prostatitis, characterized by genitourinary pain in the pelvic region in the absence of an identifiable cause, is common in adult males. Surprisingly, the sensory innervation of the prostate and mediators that sensitize its inner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56c491606f87eaafe663e150e64873d
https://doi.org/10.1097/j.pain.0000000000000201
https://doi.org/10.1097/j.pain.0000000000000201
Publikováno v:
Journal of Neurophysiology. 113:2242-2249
Measuring the excitability of individual axons is complicated by the prohibitive difficulty in obtaining intracellular recordings. Here, we present an innovative methodology that enables local excitability to be measured anywhere in a channelrhodopsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f94b2ff3f6f68c46dab57c8f3e75bb
https://doi.org/10.1152/jn.00982.2014
https://doi.org/10.1152/jn.00982.2014
Autor:
Gerald F. Gebhart, Jun-Ho La
Publikováno v:
Neurogastroenterology & Motility. 26:1730-1742
Background A low-level inflammation has been hypothesized to mediate visceral hypersensitivity in functional bowel disorders that persist after or even in the absence of gut inflammation. We aimed to test the efficacy of a steroidal anti-inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3057e46998721840a481b1de8f0f4229
https://doi.org/10.1111/nmo.12455
https://doi.org/10.1111/nmo.12455
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Afferent and efferent activities in the colorectum are governed by both intrinsic and extrinsic neuronal systems [1–5]. The extrinsic innervation of the colorectum is provided by the pelvic (PN) and lumbar splanchnic nerves [4, 5], containing both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a2c10f8c74a57829a4e1bfcb540a1d
https://doi.org/10.1111/nmo.12419
https://doi.org/10.1111/nmo.12419
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 305:G638-G648
The ligand-gated channels transient receptor potential vanilloid 1 (TRPV1) and P2X3 have been reported to facilitate colorectal afferent neuron sensitization, thus contributing to organ hypersensitivity and pain. In the present study, we hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd983eff828c0ac7104c960a1f45991
https://doi.org/10.1152/ajpgi.00180.2013
https://doi.org/10.1152/ajpgi.00180.2013