Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gerald E. Archer"'
Autor:
John H. Sampson, Kristen A Batich, Duane Anthony Mitchell, James Emmett Herndon, Gloria Broadwater, Patrick Healy, Luis Sanchez-Perez, Smita Nair, Kendra Congdon, Pamela Norberg, Kent J. Weinhold, Gerald E. Archer, Elizabeth A. Reap, Weihua Xie, Roger E. McLendon, David A. Reardon, James J. Vredenburgh, Henry S. Friedman, Darell Bigner, Allan H. Friedman
Publikováno v:
Journal of Clinical Oncology. 40:2005-2005
2005 Background: Vaccination with dendritic cells (DCs) fares poorly in primary and recurrent glioblastoma (GBM). Moreover, GBM vaccine trials are often underpowered due to limited sample size. Methods: To address these limitations, we conducted thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b454ee2defde460b94f1858d624dbe91
https://doi.org/10.1200/jco.2022.40.16_suppl.2005
https://doi.org/10.1200/jco.2022.40.16_suppl.2005
Autor:
Pamela Norberg, Elizabeth A. Reap, David M. Ashley, Kirit Singh, Gerald E. Archer, Kelly Hotchkiss, Mustafa Khasraw, Margaret Johnson, Annick Desjardins, Katherine B. Peters, John Sampson, Henry S. Friedman, Kristen A. Batich
Publikováno v:
Neuro-Oncology Advances. 3:iv5-iv5
INTRODUCTION Cytomegalovirus (CMV) antigens are excellent anti-tumor immunotherapeutic targets in glioblastoma (GBM). The PERFORMANCE trial (IRB-pro34208, IND-15846) assessed the feasibility, safety and optimal adjuvant temozolomide (TMZ) regimen to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bcf7063a8bff3b1973a6e032eede883
https://doi.org/10.1093/noajnl/vdab112.017
https://doi.org/10.1093/noajnl/vdab112.017
Autor:
John Sampson, James E. Herndon, Katherine B. Peters, Kristin Schroeder, Denise Jaggers, Eric S. Lipp, Gerald E. Archer, Duane Michell, Charlene Flahiff, Annick Desjardins, Ashley Walter, Bea Balajonda, Daniel Landi, Mustafa Khasraw, Bridget Archambault, Eric M. Thompson, Michael D. Malinzak, David M. Ashley, Evan Buckley, Margaret Johnson, Dina Randazzo
Publikováno v:
Neuro-Oncology
INTRODUCTION The cytomegalovirus (CMV) antigen, pp65, is ubiquitously expressed in malignant glioma and medulloblastoma but not in healthy brain. The objective of this Phase I trial (NCT03299309) was to assess the safety and feasibility of a novel pp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9770a8dba4bf8c65af7a5de14ad002f3
https://doi.org/10.1093/neuonc/noaa215.155
https://doi.org/10.1093/neuonc/noaa215.155
Autor:
Timothy A. Driscoll, James E. Herndon, Gerald A. Grant, John Sampson, Sridharan Gururangan, Henry S. Friedman, Duane Mitchell, Darell D. Bigner, Joanne Kurtzberg, Gerald E. Archer
We performed a phase I study to assess feasibility, safety, and efficacy of ALT+DCV following HDC +ASCR (group A) or NMAC (group B) in pts with r-PNET. METHODS: Eligible pts underwent surgery to confirm diagnosis and obtain tumor for vaccine preparat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594e50eecb3f60769bdcb5a6d80e5864
https://europepmc.org/articles/PMC6012948/
https://europepmc.org/articles/PMC6012948/
Autor:
Ahmet Atik, Peter E. Fecci, James E. Herndon, Ryan M. Schweller, Carter M. Suryadevara, Roger E. McLendon, Jennifer L. West, Luis Sanchez-Perez, John H. Sampson, Patrick Healy, Gerald E. Archer, Kendra L. Congdon
Publikováno v:
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 56
Convection Enhanced Delivery (CED) infuses therapeutic agents directly into the intracranial area continuously under pressure. The convection improves the distribution of therapeutics such as those aimed at brain tumors. Although CED successfully del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7f52231fe1a9877ac1f5859e211c90
https://pubmed.ncbi.nlm.nih.gov/30041899
https://pubmed.ncbi.nlm.nih.gov/30041899
Autor:
James E. Herndon, Henry S. Friedman, Gerald E. Archer, Weihua Xie, Patrick Healy, Stevie Threatt, Gordana Vlahovic, John H. Sampson, Kendra L. Congdon, Eric S. Lipp, Katherine B. Peters, Pamela Norberg, Luis Sanchez-Perez, Annick Desjardins
Publikováno v:
Journal of Clinical Oncology. 37:e13526-e13526
e13526 Background: Recurrence of high-grade glioma (HGG) (WHO grade III-IV) is a nearly universal phenomenon and necessitates the development of new therapeutic modalities. Two possible immunotherapeutic modalities are checkpoint blockade with agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eca20a410f26a58f0f9928c557e46e30
https://doi.org/10.1200/jco.2019.37.15_suppl.e13526
https://doi.org/10.1200/jco.2019.37.15_suppl.e13526
Autor:
Elizabeth A. Reap, Amy B. Heimberger, Elias Sayour, Robert J. Schmittling, Bryan D. Choi, John H. Sampson, James E. Herndon, Gerald E. Archer, Duane Mitchell, Luis Sanchez-Perez, Darell D. Bigner, Pamela Norberg
Publikováno v:
Cancer Immunology, Immunotherapy. 62:983-987
B lymphocyte stimulator (BLyS) is a cytokine involved in differentiation and survival of follicular B cells along with humoral response potentiation. Lymphopenia is known to precipitate dramatic elevation in serum BLyS; however, the use of this effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064d5f9517fe9ce0f67790e8d2ad118b
https://doi.org/10.1007/s00262-013-1405-y
https://doi.org/10.1007/s00262-013-1405-y
Autor:
Patrick Healy, John H. Sampson, Bryan D. Choi, Gerald E. Archer, Pamela Norberg, James E. Herndon, Robert J. Schmittling, Luis Sanchez-Perez, Elias Sayour, Anirudh Saraswathula, Elizabeth A. Reap, Kendra L. Congdon
Regulatory B cells that secrete IL-10 (IL-10(+) Bregs) represent a suppressive subset of the B cell compartment with prominent anti-inflammatory capacity, capable of suppressing cellular and humoral responses to cancer and vaccines. B lymphocyte stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a022ccd516ef342e2cf84a1a8cc9e322
https://europepmc.org/articles/PMC4746023/
https://europepmc.org/articles/PMC4746023/
Autor:
John Sampson, Darell D. Bigner, Henry S. Friedman, Katherine B. Peters, Kristen A. Batich, Elizabeth A. Reap, Patrick Healy, Denise Lally-Goss, Tulika Ranjan, Annick Desjardins, James E. Herndon, Gerald E. Archer, Allan H. Friedman, Gordana Vlahovic
BACKGROUND: Despite aggressive surgery, high-dose focused radiation, and multimechanistic chemotherapy, malignant gliomas (MG) remain almost universally fatal. The inherent biologic specificity of immunotherapy offers the prospect of targeting neopla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09f718cff2f92acb10de5777c11f693
https://europepmc.org/articles/PMC4218252/
https://europepmc.org/articles/PMC4218252/
Autor:
Weihua Xie, Smita K. Nair, Robert J. Schmittling, David Boczkowski, Gabriel De Leon, Gerald E. Archer, John Sampson, Duane Mitchell
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts Despite aggressive and incapacitating conventional therapy, glioblastoma multiforme (GBM) remains uniformly lethal. Immunotherapy in which the immune system (particularly cellular effectors such as T cells) is harnessed to specifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c961fef6f271e14a517d4da5ba601785
https://doi.org/10.1186/2051-1426-1-s1-p270
https://doi.org/10.1186/2051-1426-1-s1-p270