Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Gerald Dräger"'
Publikováno v:
Cells, Vol 12, Iss 14, p 1816 (2023)
The use of three-dimensional (3D) cell cultures has become increasingly popular in the contexts of drug discovery, disease modelling, and tissue engineering, as they aim to replicate in vivo-like conditions. To achieve this, new hydrogels are being d
Externí odkaz:
https://doaj.org/article/1d68cad68f6e433ca6ea3d241c2e1f91
Publikováno v:
Heliyon, Vol 6, Iss 1, Pp e03025- (2020)
Herewith, we report on a method that allows to simultaneously protect both the ∆14,15 bond and the carbonyl group of the symmetrical bis-steroidal diketone 2. We found that environmentally friendly and gas-free chlorination is ideally suited to ach
Externí odkaz:
https://doaj.org/article/4836cf329b9b4141badc1801535c2e99
Autor:
Jonathan Dorival, Fanny Risser, Christophe Jacob, Sabrina Collin, Gerald Dräger, Cédric Paris, Benjamin Chagot, Andreas Kirschning, Arnaud Gruez, Kira J. Weissman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The monoamine oxidase family member LkcE is an enzyme from the lankacidin polyketide biosynthetic pathway, where it catalyzes an amide oxidation followed by an intramolecular Mannich reaction, yielding the polyketide macrocycle. Here the authors char
Externí odkaz:
https://doaj.org/article/78b38c0a3e20488982c5b94105e162f4
Autor:
Diana Massai, Emiliano Bolesani, Diana Robles Diaz, Christina Kropp, Henning Kempf, Caroline Halloin, Ulrich Martin, Tudor Braniste, Giuseppe Isu, Vanessa Harms, Umberto Morbiducci, Gerald Dräger, Robert Zweigerdt
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Controlled large-scale production of human pluripotent stem cells (hPSCs) is indispensable for their envisioned clinical translation. Aiming at advanced process development in suspension culture, the sensitivity of hPSC media to continuous p
Externí odkaz:
https://doaj.org/article/5744c11d0e5c48dbaab771a3b762e064
Autor:
Monica Jara-Avaca, Henning Kempf, Michael Rückert, Diana Robles-Diaz, Annika Franke, Jeanne de la Roche, Martin Fischer, Daniela Malan, Philipp Sasse, Wladimir Solodenko, Gerald Dräger, Andreas Kirschning, Ulrich Martin, Robert Zweigerdt
Publikováno v:
Stem Cell Reports, Vol 8, Iss 2, Pp 305-317 (2017)
Subtype-specific human cardiomyocytes (CMs) are valuable for basic and applied research. Induction of cardiomyogenesis and enrichment of nodal-like CMs was described for mouse pluripotent stem cells (mPSCs) in response to 1-ethyl-2-benzimidazolinone
Externí odkaz:
https://doaj.org/article/aba0a80f0956481a9b3466538a6d3db4
Autor:
Henning Kempf, Ruth Olmer, Alexandra Haase, Annika Franke, Emiliano Bolesani, Kristin Schwanke, Diana Robles-Diaz, Michelle Coffee, Gudrun Göhring, Gerald Dräger, Oliver Pötz, Thomas Joos, Erik Martinez-Hackert, Axel Haverich, Falk F. R. Buettner, Ulrich Martin, Robert Zweigerdt
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Differentiation of human pluripotent stem cells (hPSC) mimics aspects of embryonic developmentin vitrobut is poorly understood. Here, the authors identify bulk cell density as a key parameter directing transition from pluripotency to primitive streak
Externí odkaz:
https://doaj.org/article/ea239ac1a9674180890cc009aad95741
Autor:
Pranvera Breznica-Selmani, Kristina Mladenovska, Gerald Dräger, Bozhana Mikhova, Nikola Panovski, Ana Kaftandzieva, Zoran Kavrakovski, Ahmet Hoxha, Nardi Sheqerxhiu, Maja Jurhar Pavlova, Emil Popovski
Publikováno v:
Macedonian Journal of Chemistry and Chemical Engineering, Vol 35, Iss 2, Pp 179-197 (2016)
Herein we report the synthesis of different derivatives of (fluoro)quinolones norfloxacin, ciprofloxacin and pipemidic acid, by incorporating (benzoylamino)methyl on the free nitrogen of the pyperazinyl moiety. The compounds were structurally charact
Externí odkaz:
https://doaj.org/article/5871ec40159249d5b9d00fa9d3935e18
Autor:
Jonathan Dorival, Fanny Risser, Christophe Jacob, Sabrina Collin, Gerald Dräger, Cédric Paris, Benjamin Chagot, Andreas Kirschning, Arnaud Gruez, Kira J. Weissman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/3fc8c6184d904422aa946e37fe35adc2
Autor:
Lulzime Ballazhi, Faik Imeri, Aleksandar Dimovski, Ahmed Jashari, Emil Popovski, Pranvera Breznica-Selmani, Bozhana Mikhova, Gerald Dräger, Edita Alili-Idrizi, Kristina Mladenovska
Publikováno v:
Makedonsko Farmacevtski Bilten, Vol 60, Iss (1), Pp 35-44 (2014)
Possible synergistic effect of tamoxifen (2 μM) and hydrazinyldiene-chroman-2,4-diones (10-100 μM) was examined with an aim to create more effective treatment for ER+ breast cancer. Anti-breast cancer effect has been evaluated on the proliferation
Externí odkaz:
https://doaj.org/article/97ea8f8723b643388b59835414f605ae
Publikováno v:
Catalysts, Vol 9, Iss 7, p 627 (2019)
A commercial carbon-modified titanium dioxide, KRONOClean 7000, was applied as a UV(A) and visible-light active photocatalyst to investigate the conversion of the antipsychotic pharmaceutical chlorpromazine in aqueous phase employing two monochromati
Externí odkaz:
https://doaj.org/article/45b63b28b3c64daab07a489dc0f2dd0d