Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Gerald Curzon"'
Autor:
K.E. Heslop, Gerald Curzon
Publikováno v:
Neuropharmacology. 38:883-891
Rats were given a single dose of reserpine (5 mg/kg s.c.) and behavioural responses to agonists at 5-HT receptor subtypes compared with those of control animals 21 days later. The following effects of activating postsynaptic 5-HT1A receptors by the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e210122e750da7be2b3721ed8eda50a
https://doi.org/10.1016/s0028-3908(99)00002-7
https://doi.org/10.1016/s0028-3908(99)00002-7
Publikováno v:
Neuropharmacology. 36:383-387
The effects of the (+) and (-) enantiomers of the antidepressant drug tianeptine (5, 10, 20 mg/kg, i.p.) on wet dog shakes (WDS) and faecal pellet production induced by concurrently administered 5-hydroxytryptophan (5-HTP, 100 mg/kg, i.p.) given 30 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77303074ef5085bf885a41f70b3344b0
https://doi.org/10.1016/s0028-3908(97)00016-6
https://doi.org/10.1016/s0028-3908(97)00016-6
Publikováno v:
Trends in Pharmacological Sciences. 18:21-25
The widely prescribed appetite suppressants D-fenfluramine and fluoxetine not only decrease feeding and body weight but also increase extracellular brain 5-HT. As central injection of 5-HT also decreases feeding, the drugs are often thought to requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ab9fcfe98641806a77398bf009df70
https://doi.org/10.1016/s0165-6147(96)01003-6
https://doi.org/10.1016/s0165-6147(96)01003-6
Publikováno v:
Journal of psychopharmacology (Oxford, England). 7(3)
A preliminary experiment showed that a 2.5 mg/kg dose of the 5-HT agonist 1-(3-chlorophenyl)piperazine di hydrochloride (mCPP) produced a greater reduction of food intake in female rats when weight-matched rats of both sexes were compared following 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c516051b8be1e68f8b2bd0f68290052
https://pubmed.ncbi.nlm.nih.gov/22290839
https://pubmed.ncbi.nlm.nih.gov/22290839
Publikováno v:
European Journal of Pharmacology. 264:111-115
d-Fenfluramine (2.5 mg/kg i.p.) caused marked hypophagia in food-deprived rats and significantly increased medial hypothalamic extracellular 5-hydroxytryptamine (5-HT) as indicated by in vivo microdialysis. When the drug was given after the 5-HT synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f183350b0a60c0d74269db5b2390940a
https://doi.org/10.1016/0014-2999(94)90646-7
https://doi.org/10.1016/0014-2999(94)90646-7
Publikováno v:
European Journal of Pharmacology. 255:175-183
Male and female rats were given d -fenfluramine and its effects on feeding and on hypothalamic concentrations of the drug, its metabolite norfenfluramine and 5-hydroxytryptamine (5-HT) and dopamine determined. ID 50 values (i.p.) for the hypophagic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631928854c34bce9bfa5bdf8bc3a4784
https://doi.org/10.1016/0014-2999(94)90096-5
https://doi.org/10.1016/0014-2999(94)90096-5
Autor:
K.E. Heslop, Gerald Curzon
Publikováno v:
Neuropharmacology. 33:567-573
Reserpine (5 mg/kg s.c.) was given to rats kept under a reversed light-dark cycle and 5-hydroxytryptamine (5-HT) and 5-hydroxyindole acetic acid (5-HIAA) determined in frontal cortex tissue and dialysate at various times after dug treatment. The decl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f800c0379b468f0d3a64535f5a2007
https://doi.org/10.1016/0028-3908(94)90088-4
https://doi.org/10.1016/0028-3908(94)90088-4
Publikováno v:
Neuropharmacology. 33:457-465
1-(3-Chlorophenyl)piperazine (mCPP) (0.125-1.0 mg/kg i.p.), previously shown to inhibit social interaction, dose-dependently reduced exploration of the open arms of an elevated plus-maze. These findings suggest anxiogenic properties. The effect of mC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b6877a9f220341a0d68365f3ade194
https://doi.org/10.1016/0028-3908(94)90076-0
https://doi.org/10.1016/0028-3908(94)90076-0
Publikováno v:
Scopus-Elsevier
The effects of 5-HT agonists and antagonists, benzodiazepine anxiolytics and tricyclic antidepressants on restraint stress-induced anorexia in rats were examined. The selective 5-HT1A agonists 8-hydroxy-2-(di- n-propylamino)tetralin (8-OH-DPAT), busp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d412cab7eb4a8850d7476eef6861eec4
https://pubmed.ncbi.nlm.nih.gov/22158750
https://pubmed.ncbi.nlm.nih.gov/22158750
Publikováno v:
Psychopharmacology. 113:262-268
The effects of pretreatments on behavioural responses to activation of 5-HT1C receptors by m-chlorophenylpiperazine (mCPP) were investigated. The hypo locomotor and anxiogenic effects of mCPP (social interaction test) were influenced neither by previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe9b46867e56c7502267da788fc6263
https://doi.org/10.1007/bf02245708
https://doi.org/10.1007/bf02245708