Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Gerald C Gooden"'
Autor:
Christophe R Legendre, Michael J Demeure, Timothy G Whitsett, Gerald C Gooden, Kimberly J Bussey, Sungwon Jung, Tembe Waibhav, Seungchan Kim, Bodour Salhia
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150629 (2016)
Adrenocortical carcinomas (ACC) are a rare tumor type with a poor five-year survival rate and limited treatment options.Understanding of the molecular pathogenesis of this disease has been aided by genomic analyses highlighting alterations in TP53, W
Externí odkaz:
https://doaj.org/article/17e40ea265bd4155b37e59876b490d09
Autor:
James D. Hernandez, Ben Yi Tew, Ting Li, Gerald C. Gooden, Hamza Ghannam, Mia Masuda, James Madura, Bodour Salhia, Elizabeth A. Jacobsen, Eleanna De Filippis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/88b16a2662e8414fb3bee517ff38400d
Autor:
Danny R. Welch, Bodour Salhia, Gerald C. Gooden, Christophe Legendre, Devin C. Koestler, Stefan Graw, Amanda E. Brinker, Carolyn J. Vivian
Supplemental Figure 6. Cell Cycle Analysis. Cell cycle analysis using propidium iodide (PI) staining was performed on mouse embryo fibroblasts (MEFs) harvested from the following strains: FF, FC, BB, FB, CC, CH, HH, HC (as described in Table 1). Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6abb42263a09c42216605a8d3f316cd1
https://doi.org/10.1158/0008-5472.22416038.v1
https://doi.org/10.1158/0008-5472.22416038.v1
Autor:
Danny R. Welch, Bodour Salhia, Gerald C. Gooden, Christophe Legendre, Devin C. Koestler, Stefan Graw, Amanda E. Brinker, Carolyn J. Vivian
Supplemental Figure 4. Life Span. Life span of the MNX strains was measured in days and compared to the vendor information (Jackson Laboratories for C57Bl/6 and FVB/NJ mice and Envigo Laboratories for C3H/HeN mice). N= 15 for the females. N=5 for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8cacdf077787cc8946598b4f1754215
https://doi.org/10.1158/0008-5472.22416047
https://doi.org/10.1158/0008-5472.22416047
Autor:
Danny R. Welch, Bodour Salhia, Gerald C. Gooden, Christophe Legendre, Devin C. Koestler, Stefan Graw, Amanda E. Brinker, Carolyn J. Vivian
Mitochondrial DNA (mtDNA) mutations and polymorphisms contribute to many complex diseases, including cancer. Using a unique mouse model that contains nDNA from one mouse strain and homoplasmic mitochondrial haplotypes from different mouse strain(s)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e44aa9bfa2fd9c2d3fc54dc63c0cbb7
https://doi.org/10.1158/0008-5472.c.6509450
https://doi.org/10.1158/0008-5472.c.6509450
Autor:
Danny R. Welch, Bodour Salhia, Gerald C. Gooden, Christophe Legendre, Devin C. Koestler, Stefan Graw, Amanda E. Brinker, Carolyn J. Vivian
Supplemental Figure 5. Litter sizes and gender distribution. Female to male ratios with the average litter size and total number of mice used for each strain. For the female to male ratio the average litter size was calculated from over 20 litters ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191a272ec5a7c3a74eca10c05dd3db09
https://doi.org/10.1158/0008-5472.22416041.v1
https://doi.org/10.1158/0008-5472.22416041.v1
Autor:
Danny R. Welch, Bodour Salhia, Gerald C. Gooden, Christophe Legendre, Devin C. Koestler, Stefan Graw, Amanda E. Brinker, Carolyn J. Vivian
Supplemental Figure 2. Deduplication and alignment statistics. a. Bismark v0.10.1 was used for alignment and deduplication. Duplicates were discarded using deduplicate_bismark perl script. With total number of alignments analyzed (red), total number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4c00af1a5de1d513ffe971c64e2567
https://doi.org/10.1158/0008-5472.22416053.v1
https://doi.org/10.1158/0008-5472.22416053.v1
Autor:
Danny R. Welch, Bodour Salhia, Gerald C. Gooden, Christophe Legendre, Devin C. Koestler, Stefan Graw, Amanda E. Brinker, Carolyn J. Vivian
Supplemental Figure 3. Integrative analysis of methylation and gene expression. The methylation level for the five most differentially expressed genes (listed at the top of each page), for which also methylation data was available, is shown in Panels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0bf7de9a6cfc8d10969d9b9da39d11
https://doi.org/10.1158/0008-5472.22416050
https://doi.org/10.1158/0008-5472.22416050
Autor:
Danny R. Welch, Bodour Salhia, Gerald C. Gooden, Christophe Legendre, Devin C. Koestler, Stefan Graw, Amanda E. Brinker, Carolyn J. Vivian
Supplemental Figure 7. Apoptosis Analysis. Annexin V-FITC/propidium iodide (PI) staining assay were used to measure apoptosis in MEFs harvested from the following strains: FF, FC, BB, FB, CC, CH, HH, HC (as described in Table 1). Apoptotic cells were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d3b72e2a013ca2f79f15abcfe27340
https://doi.org/10.1158/0008-5472.22416035
https://doi.org/10.1158/0008-5472.22416035
Autor:
Danny R. Welch, Bodour Salhia, Gerald C. Gooden, Christophe Legendre, Devin C. Koestler, Stefan Graw, Amanda E. Brinker, Carolyn J. Vivian
Supplemental Figure 1. Validation of Methyl-Seq and RNA-Seq. Several hypo-/hyper-methylated and down-/up-regulated genes were selected for validation using methylation specific primers (64) or quantitative PCR, respectively. Graphs depict fold-change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cb30adb7106a5fa922b41235371083
https://doi.org/10.1158/0008-5472.22416056
https://doi.org/10.1158/0008-5472.22416056