Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Gerald B, Kasting"'
Autor:
Johannes M. Nitsche, Gerald B. Kasting
Publikováno v:
Journal of Pharmaceutical Sciences. 111:2093-2106
Interpretation of experiments involving transient solute binding to isolated keratin substrates is analyzed and discussed in terms of their impact on transient permeation of topically-applied compounds through human stratum corneum. The analysis buil
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics.
Publikováno v:
Langmuir. 37:12327-12334
Sulfate-based formulations can be easily thickened by adding salt or amphoteric cosurfactants. However, sulfate-free and amino acid-based surfactants cannot. We explored an alternative thickening mechanism by studying the thickening effect of adding
Autor:
Kevin Tonnis, Johannes M. Nitsche, Lijing Xu, Alison Haley, Joanna Jaworska, Gerald B. Kasting
Publikováno v:
International journal of pharmaceutics. 624
To measure progress and evaluate performance of the newest UB/UC/PG skin penetration model we simulated an 18-compound subset of finite dose in vitro human skin permeation data taken from a solvent-deposition study of cosmetic-relevant compounds (Hew
Autor:
Suchitra Panigrahi, Amanda Barry, Scott Multner, Gerald B. Kasting, Julio A. Landero Figueroa, Latha Satish, Harshita Kumari
Publikováno v:
Pharmaceutical development and technology. 27(2)
Dupuytren's disease is a progressive fibrotic condition of the hand that causes contracture of fingers in later stages. Our previous
Autor:
Jinsong Hao, Sam G. Raney, Priyanka Ghosh, Terri D. LaCount, S. Kevin Li, Qian Zhang, Gerald B. Kasting, Michael Murawsky
Publikováno v:
J Pharm Sci
Experimental conditions that could impact the evaluation of heat effects on transdermal delivery systems (TDS) using an in vitro permeation test (IVPT) and in vitro release testing (IVRT) were examined. Fentanyl was the model TDS. IVPT was performed
Publikováno v:
Journal of Pharmaceutical Sciences. 108:3640-3648
Anionic surfactants compromise skin's barrier function by damaging stratum corneum lipids and proteins. The objective of this study was to examine anionic surfactant–induced changes in the skin's polar and transcellular pathways and the resulting i
Autor:
Kavssery Parameswaran Ananthapadmanabhan, Gerald B. Kasting, Stephanie A. V. Morris, Lijing Xu
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 37(48)
Surfactant mixtures are used in a variety of personal care and cosmetic applications but are known to be harsh on the skin. The purpose of this study was to examine anionic surfactant penetration into human skin from nonideal surfactant mixtures unde
Publikováno v:
Journal of pharmaceutical sciences. 111(3)
A quantitative understanding of the dose dependence of topical delivery is important to cosmetic and dermatological product development and to risk assessment for hazardous chemicals contacting the skin. Despite considerable research, predictive capa
Autor:
Kavssery Parameswaran Ananthapadmanabhan, Stephanie A.V. Morris, Gerald B. Kasting, Jessica R. Bobbitt
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 77
The purpose of this study was to examine the effect of prolonged surfactant exposure on mechanisms of anionic surfactant penetration into human skin. A radiolabeled probe (14-carbon sodium dodecyl sulfate (14C-SDS)) was used to trace the penetration