Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Gerald A. Rosenthal"'
Autor:
Gerald A. Rosenthal
Publikováno v:
Amino Acids. 21:319-330
L-Canavanine, L-2-amino-4-(guanidinooxy)butyric acid, is a potentially toxic nonprotein amino acid of certain leguminous plants. Many species are prolific canavanine producers; they divert enormous nitrogen resource to the storage of this single natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8a85c23bb9acf2bec0cdcf4d214639
https://doi.org/10.1007/s007260170017
https://doi.org/10.1007/s007260170017
Autor:
Palesa Nkomo, Gerald A. Rosenthal
Publikováno v:
Pharmaceutical Biology. 38:1-6
L-Canavanine, a potentially toxic antimetabolite of L-arginine that is stored by many leguminous plants, has demonstrative antineoplastic activity against a number of animal-bearing carcinomas and cancer cell lines. This investigation evaluated the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d3f08b4ad8440fc7f909584f94a51a
https://doi.org/10.1076/1388-0209(200001)3811-bft001
https://doi.org/10.1076/1388-0209(200001)3811-bft001
Autor:
Supinan R. Na Phuket, Latchezar S. Trifonov, Chongxi Yu, David R. Worthen, Peter A. Crooks, Gerald A. Rosenthal, James W. Freeman
Publikováno v:
Drug Development Research. 47:170-177
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceac89fd2df647dc9c98678e9ee0f7af
https://doi.org/10.1002/(sici)1098-2299(199908)47:4<170::aid-ddr3>3.0.co
https://doi.org/10.1002/(sici)1098-2299(199908)47:4<170::aid-ddr3>3.0.co
Autor:
Gerald A. Rosenthal, Naoko Ohtani-Fujita, Yi Ding, Yoshizumi Matsukawa, Toshiyuki Sakai, Takaaki Fujii, Daishiro Kato, Yuji Naito, Su Dao, Toshikazu Yoshikawa
Publikováno v:
Japanese Journal of Cancer Research : Gann
L-Canavanine (CAV) is a higher plant nonprotein amino acid and a potent L-arginine antimetabolite. CAV can inhibit the proliferation of tumor cells in vitro and in vivo, but little is known regarding the molecular mechanisms mediating these effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e2c43a37e4c711cdd53ddeed6c081e
http://europepmc.org/articles/PMC5925972
http://europepmc.org/articles/PMC5925972
Autor:
G. Lubec, Gerald A. Rosenthal
There is little wonder in the fact that the investigation of amino acids is of fundamental interest to scientists from so many diversified fields. If amino acids were only basic constituents of enzymes as well as structural and other proteins, this p
Autor:
Gerald A. Rosenthal
Publikováno v:
Biochemical Systematics and Ecology. 26:257-266
A group of seven naturally-occurring, potentially toxic nonprotein amino acid antimetabolites, namely l -azetidine-2-carboxylic acid, l -homoarginine, l -canavanine, 5-hydroxy- l -lysine, l -albizzine, seleno- l -methionine, or 2-aminoethyl- l -cyste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15b3aaadb2c606f67e1a6383822738f5
https://doi.org/10.1016/s0305-1978(97)00100-2
https://doi.org/10.1016/s0305-1978(97)00100-2
Publikováno v:
Journal of Agricultural and Food Chemistry. 46:296-299
The ability of the several esters of L-canavanine, a potentially insecticidal natural product of leguminous plants, to enhance the potency of the parent compound was evaluated with the propyl, butyl, isobutyl, and octyl esters of L-canavanine. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2113154d6a737d4f8d1e47ec8a97ee8a
https://doi.org/10.1021/jf970558z
https://doi.org/10.1021/jf970558z
Autor:
Gerald A. Rosenthal
Publikováno v:
Pharmaceutical Biology. 36:194-201
L-Canavanine, the principal nonprotein amino acid of certain leguminous plants, is a potent L-arginine antimetabolite. This natural product has demonstrative antineoplastic activity against a number of human cancers. Recent studies with MIAPaCa-2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e367c41787def933a32866ee212033c
https://doi.org/10.1076/phbi.36.3.194.6340
https://doi.org/10.1076/phbi.36.3.194.6340
Autor:
William E. Strodel, Peter A. Crooks, James W. Freeman, Latchezar S. Trifonov, Gerald A. Rosenthal, Supinan R. Na Phuket
Publikováno v:
Drug Development Research. 40:325-332
A number of congeners of the antitumor compound L-canaline, [l-2-amino-4-(aminooxy)butyric acid], a structural analog of L-ornithine, have been synthesized and their growth-inhibitory effects evaluated in cultured MIA-PaCa-2 cells, a human pancreatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ab6ed4123c18cef3f1837989af5d8d9
https://doi.org/10.1002/(sici)1098-2299(199704)40:4<325::aid-ddr6>3.0.co
https://doi.org/10.1002/(sici)1098-2299(199704)40:4<325::aid-ddr6>3.0.co
Autor:
Gerald A. Rosenthal
Publikováno v:
Life Sciences. 60:1635-1641
L-Canaline, the L-2-amino-4-(aminooxy)butyric acid structural analog of L-ornithine' is a powerful antimetabolite stored in many leguminous plants. This nonprotein amino acid reacts vigorously with the pyridoxal phosphate moiety of vitamin B6-contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8fb3ef5ef36777cf5c2d219fb469a0
https://doi.org/10.1016/s0024-3205(96)00595-4
https://doi.org/10.1016/s0024-3205(96)00595-4